Cited by 212Race, Genetics, and SocietyMedical History and ResearchBioethics and Human Rights Issues

Epigenetic life: biological plasticity, abnormality, and new configurations of race and reproduction

Open access
Mansfield, Becky, Guthman, Julie·2015·cultural geographies

Abstract

Environmental epigenetics is a ‘hot’ new field of post-genomic science investigating mechanisms that influence how genes are expressed. It offers a dynamic and non-dualistic understanding of the relationship between environments, genes, bodies, and health. We ask how this new science of biological plasticity is changing existing concepts of normality and abnormality. We find that epigenetics is contributing to a new biological (yet non-determinist) ontology of race and that the fetus and reproductive women are emerging as the central figures in this new epigenetic model of race and bodily plasticity. We find that epigenetics is a science of variation in which biological difference is figured as both normal (inevitable) and abnormal (a sign of disruption); it then seeks to improve life by identifying therapies to cure epigenetic ‘abnormalities’. In this way, epigenetics emerges as a reproductive science, in which the ‘uterine environment’ is figured as the key space–time of epigenetic becoming. We argue that in this focus on abnormality and improvement, epigenetics is tied to a eugenic logic, even as it rejects notions of genetic determinism. While it might seem that epigenetic models of plastic life should eliminate race by eliminating notions of discrete kinds given in nature, it appears that epigenetics offers a new form of racialization based on reproductive processes of becoming rather than on pre-given nature.

Integrity signals

Registry

Crossref · 10.1177/1474474014555659

Cites

2 of 2 references verified0 citation errors · 0 not checkable

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  • The focus on pregnancy as a critical period for epigenetic modifications has increased the stakes of intervening on pregnant people diagnosed as overweight and obese in an attempt to control future health.

    “The focus on pregnancy as a critical period for epigenetic modifications has increased the stakes of intervening on pregnant people diagnosed as overweight and obese in an attempt to control future health (Mansfield and Guthman 2015; Warin et al. 2015; Valdez 2018).”

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Authors
Mansfield, B., & Guthman, J.
Affiliations
  • The Ohio State University (US)
  • University of California, Santa Cruz (US)
Venue
cultural geographies
Published
2014-11-03
Volume
22
Issue
1
Pages
3-20
ISSN
  • 0967-4608 (ISSN-L)
  • 1474-4740
  • 1477-0881
OpenAlex
W2106823244
Cited by
212
References
2
Citations by year
2026: 12 · 2025: 7 · 2024: 21 · 2023: 15 · 2022: 64 · 2021: 18 · 2020: 15 · 2019: 21 · 2018: 12 · 2017: 15 · 2016: 11 · 2015: 1
FWCI
5.90
Type
journal article
Language
en
Open access
Locations
Cultural Geographies (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Race, Genetics, and Society
  • Social Sciences › Arts and Humanities › History › Medical History and Research
  • Physical Sciences › Computer Science › Information Systems › Bioethics and Human Rights Issues
Keywords
environmental epigenetics, biological plasticity, race, abnormality, normality, reproductive science, fetal development, uterus, eugenics, racialization, epigenetic therapy

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