Epigenetic life: biological plasticity, abnormality, and new configurations of race and reproduction
Open accessAbstract
Environmental epigenetics is a ‘hot’ new field of post-genomic science investigating mechanisms that influence how genes are expressed. It offers a dynamic and non-dualistic understanding of the relationship between environments, genes, bodies, and health. We ask how this new science of biological plasticity is changing existing concepts of normality and abnormality. We find that epigenetics is contributing to a new biological (yet non-determinist) ontology of race and that the fetus and reproductive women are emerging as the central figures in this new epigenetic model of race and bodily plasticity. We find that epigenetics is a science of variation in which biological difference is figured as both normal (inevitable) and abnormal (a sign of disruption); it then seeks to improve life by identifying therapies to cure epigenetic ‘abnormalities’. In this way, epigenetics emerges as a reproductive science, in which the ‘uterine environment’ is figured as the key space–time of epigenetic becoming. We argue that in this focus on abnormality and improvement, epigenetics is tied to a eugenic logic, even as it rejects notions of genetic determinism. While it might seem that epigenetic models of plastic life should eliminate race by eliminating notions of discrete kinds given in nature, it appears that epigenetics offers a new form of racialization based on reproductive processes of becoming rather than on pre-given nature.
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The focus on pregnancy as a critical period for epigenetic modifications has increased the stakes of intervening on pregnant people diagnosed as overweight and obese in an attempt to control future health.
“The focus on pregnancy as a critical period for epigenetic modifications has increased the stakes of intervening on pregnant people diagnosed as overweight and obese in an attempt to control future health (Mansfield and Guthman 2015; Warin et al. 2015; Valdez 2018).”
From The Politics of Postgenomic Reproduction: Exploring Pregnant Narratives from within a Clinical Trial (2022) · cites this paper as Mansfield and Guthman 2015
Cites
Faulk, C., & Dolinoy, D. C. (2011) · Epigenetics · doi:10.4161/epi.6.7.16209 · Cited by 386 · see citing works
Szyf, M. (2011) · Epigenetics · doi:10.4161/epi.6.8.16793 · Cited by 161 · see citing works
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Environmental Politics of Reproduction
Lappé, M., Jeffries Hein, R., & Landecker, H. (2019) · Annual Review of Anthropology · doi:10.1146/annurev-anthro-102218-011346 · Cited by 102 · see citing works
The Politics of Postgenomic Reproduction: Exploring Pregnant Narratives from within a Clinical Trial
Valdez, N. (2022) · Science, Technology, & Human Values · doi:10.1177/01622439211066759 · Cited by 4 · see citing works
- Authors
- Mansfield, B., & Guthman, J.
- Affiliations
- The Ohio State University (US)
- University of California, Santa Cruz (US)
- Venue
- cultural geographies
- Publisher
- SAGE Publications
- Published
- 2014-11-03
- Volume
- 22
- Issue
- 1
- Pages
- 3-20
- ISSN
- 0967-4608 (ISSN-L)
- 1474-4740
- 1477-0881
- OpenAlex
- W2106823244
- Cited by
- 212
- References
- 2
- Citations by year
- 2026: 12 · 2025: 7 · 2024: 21 · 2023: 15 · 2022: 64 · 2021: 18 · 2020: 15 · 2019: 21 · 2018: 12 · 2017: 15 · 2016: 11 · 2015: 1
- FWCI
- 5.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cultural Geographies (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Race, Genetics, and Society
- Social Sciences › Arts and Humanities › History › Medical History and Research
- Physical Sciences › Computer Science › Information Systems › Bioethics and Human Rights Issues
- Keywords
- environmental epigenetics, biological plasticity, race, abnormality, normality, reproductive science, fetal development, uterus, eugenics, racialization, epigenetic therapy
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