Alcohol Consumption Increases Periodontitis Risk

Pitiphat, W.; Merchant, A.T.; Rimm, E.B.; Joshipura, K.J.

doi:10.1177/154405910308200704

Cited by 155Oral microbiology and periodontitis researchAlcohol Consumption and Health EffectsDental Health and Care Utilization

Alcohol Consumption Increases Periodontitis Risk

Pitiphat, W., Merchant, A.T., Rimm, E.B., Joshipura, K.J.·2003·Journal of Dental Research

DOI 10.1177/154405910308200704

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Abstract

Alcohol consumption impairs neutrophil, macrophage, and T-cell functions, increasing the likelihood of infections. We examined the association between alcohol consumption and periodontitis, prospectively, among 39,461 male health professionals aged 40 to 75 years and free of periodontitis at the start of follow-up. Alcohol intake was assessed at baseline and updated every 4 years by a food-frequency questionnaire. Periodontal disease status was self-reported and validated against radiographs. Multivariate analysis was adjusted for age, smoking, diabetes, body-mass index, physical activity, time period, and caloric intake. During 406,160 person-years of follow-up, there were 2125 cases of periodontitis. Compared with non-drinkers, the relative risk (95% confidence interval) among men reporting usual alcohol intake of 0.1-4.9 g/day was 1.24 (1.09, 1.42); 5.0 to 14.9 g/day, 1.18 (1.04, 1.35); 15 to 29.9 g/day, 1.18 (1.01, 1.38); and > 30 g/day, 1.27 (1.08, 1.49). The results suggest that alcohol consumption is an independent modifiable risk factor for periodontitis.

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Dysbiosis is prompted by various factors, including host diet, inflammatory responses, systemic disruptions, and habits such as alcohol intake, smoking tobacco and consuming alcohol.
“Such dysbiosis is prompted by various factors, including host diet, inflammatory responses, systemic disruptions, and habits such as alcohol intake, smoking tobacco and consuming alcohol.50, 180, 181, 182, 183, 184, 185, 186”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [186]

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Alcohol Consumption, Risk of Periodontitis and Change of Periodontal Parameters in a Population‐Based Cohort Study
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Alcohol Consumption Increases Periodontitis Risk Published by:
(2015)
Alcohol consumption and risk of periodontitis: a meta‐analysis
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Authors: Pitiphat, W., Merchant, A. T., Rimm, E. B., & Joshipura, K. J.
Affiliations: Brigham and Women's Hospital (US)
ORCID: Pitiphat, W.
Merchant, A.T.
Rimm, E.B.
Joshipura, K.J.
Venue: Journal of Dental Research
Publisher: SAGE Publications
Published: 2003-07
Volume: 82
Issue: 7
Pages: 509-513
ISSN: 0022-0345 (ISSN-L)
1544-0591
DOI: 10.1177/154405910308200704
OpenAlex: W2076305238
Cited by: 155
References: 30
Citations by year: 2026: 3 · 2025: 6 · 2024: 4 · 2023: 4 · 2022: 8 · 2021: 13 · 2020: 10 · 2019: 5 · 2018: 8 · 2017: 6 · 2016: 8 · 2015: 9 · 2014: 8 · 2013: 8 · 2012: 7
FWCI: 6.94
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Dental Research (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute on Alcohol Abuse and Alcoholism (AA-11181, R01AA011181)
National Heart, Lung, and Blood Institute (R01HL035464, HL35464)
National Cancer Institute (CA-55075)
National Institute of Dental and Craniofacial Research (DE-12102, R01DE012102)
Topics: Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
Keywords: alcohol consumption, periodontitis, periodontal risk factors, modifiable risk factors, immune function, prospective cohort
MeSH terms: Adult, Aged, Alcohol Drinking, Humans, Male, Middle Aged, Periodontitis, Prospective Studies, Surveys and Questionnaires, Risk, Risk Factors, Smoking, Logistic Models, Proportional Hazards Models

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Alcohol Consumption Increases Periodontitis Risk

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