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Cited by 280

The DOI matches its Crossref record; 116 of the 116 references it cites were found in a registry or an index.

Review: Deep brain stimulation in Parkinson’s disease

Open access
Groiss, S.J., Wojtecki, L., Südmeyer, M., Schnitzler, A.·2009·Therapeutic Advances in Neurological Disorders

Abstract

During the last 15 years deep brain stimulation (DBS) has been established as a highly-effective therapy for advanced Parkinson’s disease (PD). Patient selection, stereotactic implantation, postoperative stimulator programming and patient care requires a multi-disciplinary team including movement disorders specialists in neurology and functional neurosurgery. To treat medically refractory levodopa-induced motor complications or resistant tremor the preferred target for high-frequency DBS is the subthalamic nucleus (STN). STN-DBS results in significant reduction of dyskinesias and dopaminergic medication, improvement of all cardinal motor symptoms with sustained long-term benefits, and significant improvement of quality of life when compared with best medical treatment. These benefits have to be weighed against potential surgery-related adverse events, device-related complications, and stimulus-induced side effects. The mean disease duration before initiating DBS in PD is currently about 13 years. It is presently investigated whether the optimal timing for implantation may be at an earlier disease-stage to prevent psychosocial decline and to maintain quality of life for a longer period of time.

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Metadata

Authors
Groiss, S. J., Wojtecki, L., Südmeyer, M., & Schnitzler, A.
Venue
Therapeutic Advances in Neurological Disorders
Published
2009-09-18
Volume
2
Issue
6
Pages
379-391
ISSN
  • 1756-2856 (ISSN-L)
  • 1756-2864
OpenAlex
W1480945180
Cited by
280
References
116
FWCI
2.81
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Review: Deep brain stimulation in Parkinson’s disease. https://app.cochat.ai/papers/10.1177/1756285609339382
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Groiss, S. J., Wojtecki, L., Südmeyer, M., & Schnitzler, A. (2009). Review: Deep brain stimulation in Parkinson’s disease. Therapeutic Advances in Neurological Disorders. https://doi.org/10.1177/1756285609339382

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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