Cited by 5Diabetes Management and ResearchIntravenous Infusion Technology and SafetyDiabetes Management and Education

Description of a Novel Patch Pump for Insulin Delivery and Comparative Accuracy Evaluation

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Baumstark, Annette, Mende, Jochen, Uchiyama, Joji, Haug, Cornelia, Freckmann, Guido·2022·Journal of Diabetes Science and Technology

Abstract

A new insulin patch pump for continuous subcutaneous insulin infusion was developed. The pump is composed of reusable and disposable parts and operates with a stepping motor. This pump was compared to a patch pump and a durable pump regarding basal rate and bolus accuracy. Using a microgravimetric method, boluses of 0.2 U, 1 U and 7 U, and a basal rate of 1 U/h were tested. For all pumps, bolus accuracy was higher when larger volumes were delivered. While median deviations were similar for all pumps, there were differences in the precision of individual boluses and when regarding basal rate delivery divided into 1-h windows.

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  • The prototype's delivery accuracy is similar or even better than that of all commercially available pumps tested in a comparable experimental setting.

    “Our study results suggest that the tested pump prototype provides delivery accuracy and occlusion detection that is similar or even better compared to all commercially available pumps tested with a similar experimental approach.”
  • Deviations from target for the prototype were similar or lower compared to other patch pumps currently available on the market tested in a similar experimental setting.

    “However, the results of this investigation showed that deviations from target were similar or lower compared to other patch pumps currently available on the market and that have been tested in a similar experimental setting. 7,8”

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References 5 · Cited by 5

Research works printed but not linked: 4

  1. [1]Pozzilli P Battelino T Danne T Hovorka R Jarosz-Chobot P Renard E. Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics. Diabetes Metab Res Rev. 2016; 32(1): 21- 39. 25865292 PMC5033023
  2. [3]Kamecke U Waldenmaier D Haug C Ziegler R Freckmann G. Establishing methods to determine clinically relevant bolus and basal rate delivery accuracy of insulin pumps. J Diabetes Sci Technol. 2019; 13(1): 60- 67. 30003823 PMC6313283
  3. [4]Freckmann G Kamecke U Waldenmaier D Haug C Ziegler R. Accuracy of bolus and basal rate delivery of different insulin pump systems. Diabetes Technol Ther. 2019; 21(4): 201- 208. 30901232 PMC6477586
  4. [5]Ziegler R Waldenmaier D Kamecke U Mende J Haug C Freckmann G. Accuracy assessment of bolus and basal rate delivery of different insulin pump systems used in insulin pump therapy of children and adolescents. Pediatr Diabetes. 2020; 21: 649- 656. 32003490

Authors
Baumstark, A., Mende, J., Uchiyama, J., Haug, C., & Freckmann, G.
Affiliations
  • Universität Ulm (DE)
  • Terumo (Japan) (JP)
Corresponding author
Baumstark, Annette
Venue
Journal of Diabetes Science and Technology
Published
2021-03-19
Volume
16
Issue
4
Pages
971-975
ISSN
1932-2968 (ISSN-L)
OpenAlex
W3139348616
Cited by
5
References
5
Citations by year
2026: 2 · 2025: 1 · 2023: 1 · 2022: 1
FWCI
0.37
Type
journal article
Language
en
Open access
Locations
  • Journal of Diabetes Science and Technology (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
Terumo Europe NV
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Physical Sciences › Engineering › Biomedical Engineering › Intravenous Infusion Technology and Safety
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords
insulin pump therapy, insulin delivery
MeSH terms
Humans, Hypoglycemic Agents, Insulin, Insulin Infusion Systems

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