Neurology of Acute Viral Infections
Open accessAbstract
As specialists in acute neurology, neurohospitalists are often called upon to diagnose and manage acute viral infections affecting the nervous system. In this broad review covering the neurology of several acute viral infections, our aim is to provide key diagnostic and therapeutic pearls of practical use to the busy neurohospitalist. We will review acute presentations, diagnosis, and treatment of human herpesviruses, arboviruses, enteroviruses, and some vaccine-preventable viruses. The neurological effects of coronaviruses, including COVID-19, are not covered in this review.
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HHV-6 can cause severe CNS disease, especially in immunocompromised hosts, but a positive HHV-6 finding may also result from subclinical reactivation of the latent virus or chromosomal integration and may not be relevant for the CNS infection.
“Although HHV-6 can cause severe CNS disease, especially in immunocompromised hosts, a positive HHV-6 finding may also result from subclinical reactivation of the latent virus or chromosomal integration and may not be relevant for the CNS infection (26–29).”
From Evaluation of the Novel CE-IVD-Marked Multiplex PCR QIAstat-Dx Meningitis/Encephalitis Panel (2023) · cites this paper as [29]
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Cited by
Sorted by citations
Evaluation of the Novel CE-IVD-Marked Multiplex PCR QIAstat-Dx Meningitis/Encephalitis Panel
Humisto, A., Antikainen, J., Holma, T., Jarva, H., Toivonen, A., Loginov, R., & Mannonen, L. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.05144-22 · Cited by 21 · see citing works
- Authors
- Krett, J. D., Beckham, J. D., Tyler, K. L., Piquet, A. L., Chauhan, L., Wallace, C. J., Pastula, D. M., & Kapadia, R. K.
- Affiliations
- University of Calgary (CA)
- University of Colorado Anschutz (US)
- Colorado School of Public Health (US)
- Corresponding author
- Kapadia, Ronak K
- ORCID
- Venue
- The Neurohospitalist
- Publisher
- SAGE Publications
- Published
- 2022-05-27
- Volume
- 12
- Issue
- 4
- Pages
- 632-646
- ISSN
- 1941-8744 (ISSN-L)
- 1941-8752
- PMC
- PMC9485684
- OpenAlex
- W4281659487
- Cited by
- 13
- References
- 5
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 2
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The Neurohospitalist (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Health Sciences › Medicine › Epidemiology › Herpesvirus Infections and Treatments
- Keywords
- acute viral infection, human herpesviruses, arboviruses, enterovirus, neurological diagnosis, neurological treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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