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Testing a Hierarchical Model of Neuroticism and Its Cognitive Facets: Latent Structure and Prospective Prediction of First Onsets of Anxiety and Unipolar Mood Disorders During 3 Years in Late Adolescence
Open accessAbstract
Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood disorders (UMDs) and anxiety disorders (ADs). However, it is unclear whether the associations of these vulnerabilities with these disorders are attributable to a latent variable common to all vulnerabilities, more narrow latent variables, or both. Additionally, some suggest that neuroticism predicts UMDs, ADs, and substance use disorders (SUDs) with comparable strength whereas others hypothesize that neuroticism is more strongly related to UMDs and ADs. We tested hypotheses about the factor structure of several vulnerabilities and the prospective associations of these latent variables with initial onsets of UMDs, ADs, and SUDs over three years in 547 participants recruited as high school juniors. Although a general neuroticism factor predicted SUDs, it predicted UMDs and ADs more strongly and especially predicted comorbid UMDs and ADs. There was also mixed support for specific associations involving more narrow latent vulnerabilities.
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“and a core vulnerability factor common to anxiety and mood disorders (32).”
From Decreases in State and Trait Anxiety Post-psilocybin: A Naturalistic, Observational Study Among Retreat Attendees (2022) · cites this paper as [32]
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Metadata
- Authors
- Zinbarg, R. E., Mineka, S., Bobova, L., Craske, M. G., Vrshek-Schallhorn, S., Griffith, J. W., Wolitzky-Taylor, K., Waters, A. M., Sumner, J. A., & Anand, D.
- Affiliations
- Northwestern University (US)
- University of California, Los Angeles (US)
- Department of Psychology, Northwestern University
- Corresponding author
- Zinbarg, Richard E.
- ORCID
- Venue
- Clinical Psychological Science
- Publisher
- SAGE Publications
- Published
- 2016-06-23
- Volume
- 4
- Issue
- 5
- Pages
- 805-824
- ISSN
- 2167-7026 (ISSN-L)
- 2167-7034
- PMC
- PMC13021253
- OpenAlex
- W2267227323
- Cited by
- 123
- References
- 110
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 16 · 2023: 8 · 2022: 11 · 2021: 15 · 2020: 21 · 2019: 9 · 2018: 12 · 2017: 17 · 2016: 4
- FWCI
- 19.86
- Type
- journal article
- Language
- en
- Open access
- green
- pmc.ncbi.nlm.nih.gov
- Licence
- Locations
- Clinical Psychological Science (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Griffith Research Online (submittedVersion, other-oa)
- Funders
- Northwestern University
- Griffith University
- Feinberg School of Medicine
- National Institute of Mental Health (R01MH065652, R01MH065651)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- neuroticism, unipolar mood disorders, anxiety disorders, substance use disorders, comorbidities, factor structure, high school students
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