The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Recognizing and Managing Chronic Graft-Versus-Host Disease
Open accessAbstract
Chronic graft-versus-host disease (GVHD) is an immune-mediated disorder that occurs frequently after allogeneic hematopoietic cell transplantation (HCT). Most cases are diagnosed within the first year at a median of 4 to 6 months after HCT, but 5–10% of cases are initially diagnosed beyond the first post-transplant year. Chronic GVHD most often involves the skin and mouth, but almost any other organ system can be involved. Correct diagnosis is critical so that appropriate therapy can be started promptly to minimize symptoms and prevent irreversible organ damage. Initial treatment should be with cortico-steroid-based therapy. Optimal secondary treatment as not been established, although a large number of agents may provide benefits. A 2004 NIH conference focused on development of consensus criteria for chronic GVHD. Six papers published in 2005 and 2006 propose consensus definitions for chronic GVHD diagnosis and scoring, pathology, biomarkers, response criteria, supportive care and design of clinical trials. This review will focus on common clinical presentations and principles for managing chronic GVHD. The most frequently used secondary therapies and ongoing trials are summarized. New concepts from the NIH consensus conference are discussed.
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Jagasia, M. H., Greinix, H. T., Arora, M., Williams, K. M., Wolff, D., Cowen, E. W., Palmer, J., Weisdorf, D., Treister, N. S., Cheng, G.-S., et al. (2015) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2014.12.001 · Cited by 5,459
Self-citationFilipovich, A. H., Weisdorf, D., Pavletic, S., Socie, G., Wingard, J. R., Lee, S. J., Martin, P., Chien, J., Przepiorka, D., Couriel, D., et al. (2005) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2005.09.004 · Cited by 3,556
Self-citationChronic graft-versus-host disease
Lee, S. J., Vogelsang, G., & Flowers, M. E. D. (2003) · Biology of Blood and Marrow Transplantation · doi:10.1053/bbmt.2003.50026 · Cited by 950
Self-citationLong-Term Survival and Late Deaths after Allogeneic Bone Marrow Transplantation
Socié, G., Stone, J. V., Wingard, J. R., Weisdorf, D., Henslee-Downey, P. J., Bredeson, C., Cahn, J.-Y., Passweg, J. R., Rowlings, P. A., Schouten, H. C., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907013410103 · Cited by 698
(2000) · Biology of Blood and Marrow Transplantation · doi:10.1016/s1083-8791(00)70002-4 · Cited by 607
Pavletic, S. Z., Martin, P., Lee, S. J., Mitchell, S., Jacobsohn, D., Cowen, E. W., Turner, M. L., Akpek, G., Gilman, A., McDonald, G., et al. (2006) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2006.01.008 · Cited by 563
Self-citationLee, S. J. (2002) · Blood · doi:10.1182/blood.v100.2.406 · Cited by 538
Self-citationRituximab for steroid-refractory chronic graft-versus-host disease
Cutler, C., Miklos, D., Kim, H. T., Treister, N., Woo, S.-B., Bienfang, D., Klickstein, L. B., Levin, J., Miller, K., Reynolds, C., et al. (2006) · Blood · doi:10.1182/blood-2006-01-0233 · Cited by 452
Self-citationFlowers, M. E. D., Parker, P. M., Johnston, L. J., Matos, A. V. B., Storer, B., Bensinger, W. I., Storb, R., Appelbaum, F. R., Forman, S. J., Blume, K. G., et al. (2002) · Blood · doi:10.1182/blood-2002-01-0011 · Cited by 421
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Cited by
Majhail, N. S., Rizzo, J. D., Lee, S. J., Aljurf, M., Atsuta, Y., Bonfim, C., Burns, L. J., Chaudhri, N., Davies, S., Okamoto, S., et al. (2012) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2011.12.519 · Cited by 363
Self-citationMajhail, N. S., Rizzo, J. D., Lee, S. J., Aljurf, M., Atsuta, Y., Bonfim, C., Burns, L. J., Chaudhri, N., Davies, S., Okamoto, S., et al. (2012) · Bone Marrow Transplantation · doi:10.1038/bmt.2012.5 · Cited by 248
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Metadata
- Authors
- Lee, S. J., & Flowers, M. E. D.
- Venue
- Hematology
- Publisher
- American Society of Hematology
- Published
- 2008-01-01
- Volume
- 2008
- Issue
- 1
- Pages
- 134-141
- ISSN
- 1520-4383 (ISSN-L)
- 1520-4391
- OpenAlex
- W2078062413
- Cited by
- 261
- References
- 30
- FWCI
- 5.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Lee, S. J., & Flowers, M. E. D. (2008). Recognizing and Managing Chronic Graft-Versus-Host Disease. Hematology. https://doi.org/10.1182/asheducation-2008.1.134
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
