The extracellular matrix protein mindin serves as an integrin ligand and is critical for inflammatory cell recruitment

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Akt: A Therapeutic Target in Hepatic Ischemia–Reperfusion Injury

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The pattern-recognition molecule mindin binds integrin Mac-1 to promote macrophage phagocytosis via Syk activation and NF-κB p65 translocation

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Autism spectrum disorders and natural killer cells: a review on pathogenesis and treatment

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The effects of extracellular matrix proteins on neutrophil-endothelial interaction--a roadway to multiple therapeutic opportunities.

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Mindin deficiency alleviates renal fibrosis through inhibiting NF‐κB and TGF‐β/Smad pathways

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Elevated spondin-2 expression correlates with progression and prognosis in gastric cancer

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Spondin2 is a new prognostic biomarker for lung adenocarcinoma

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Long-Term Effects of Very Low Dose Particle Radiation on Gene Expression in the Heart: Degenerative Disease Risks

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Mindin is upregulated during colitis and may activate NF-κB in a TLR-9 mediated manner

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A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

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Corrigendum: Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis

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Mindin Activates Autophagy for Lipid Utilization and Facilitates White Spot Syndrome Virus Infection in Shrimp

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A Wrinkle in TIME: How Changes in the Aging ECM Drive the Remodeling of the Tumor Immune Microenvironment

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Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

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Upregulation of Spondin-2 protein expression correlates with poor prognosis in hepatocellular carcinoma

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Role of extra cellular proteins in gastric cancer progression and metastasis: an update

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The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace

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Role of Mindin in Diabetic Nephropathy

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SPON2 facilitates osteosarcoma development by inducing M2 macrophage polarization through activation of the NF-κB/VEGF signaling axis

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Characterization of the early molecular changes in the glomeruli of Cd151 −/− mice highlights induction of mindin and MMP-10

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Evaluation of serum S pondin 2 levels in the different stages of T ype 2 diabetic nephropathy

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Mindin (SPON2) Is Essential for Cutaneous Fibrogenesis in a Mouse Model of Systemic Sclerosis

Rana, I., Kataria, S., Tan, T. L., Hajam, E. Y., Kashyap, D. K., Saha, D., Ajnabi, J., Paul, S., Jayappa, S., Ananthan, A. S., et al. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.10.011 · Cited by 13 · see citing works

MACC1-induced migration in tumors: Current state and perspective

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Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-β

Zhang, C., Qin, J., Gong, F., Tong, J.-J., Cheng, W., Wang, H., Zhang, Y., Zhu, X., She, Z., Xia, H., et al. (2018) · Clinical Science · doi:10.1042/cs20180033 · Cited by 13 · see citing works

Deconvolution of RNA-Seq Analysis of Hyperbaric Oxygen-Treated Mice Lungs Reveals Mesenchymal Cell Subtype Changes

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The secreted matrix protein mindin increases prostate tumor progression and tumor-bone crosstalk via ERK 1/2 regulation

Ardura, J. A., Gutiérrez-Rojas, I., Álvarez‐Carrión, L., Rodríguez-Ramos, M. R., Pozuelo, J. M., & Alonso, V. (2019) · Carcinogenesis · doi:10.1093/carcin/bgz105 · Cited by 12 · see citing works

Hyperlipidemia and Allograft Rejection

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Knockdown of SPON2 inhibits the growth of triple-negative breast cancer

Hu, X., Su, C., & Wei, J. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1141417 · Cited by 11 · see citing works

Mindin serves as a tumour suppressor gene during colon cancer progression through MAPK/ERK signalling pathway in mice

Cheng, X., Huo, Y., Fan, Y., Xiao, C., Ouyang, X., Liang, L., Lin, Y., Wu, J., Ren, J., & Guleng, B. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15332 · Cited by 11 · see citing works

Spondin-2 is a novel diagnostic biomarker for laryngeal squamous cell carcinoma

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Study of Human T21 Placenta Suggests a Potential Role of Mesenchymal Spondin-2 in Placental Vascular Development

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Integrative Analysis of DNA Methylation and Transcriptome Identifies a Predictive Epigenetic Signature Associated With Immune Infiltration in Gliomas

Zhang, J., Yin, J., Luo, L., Huang, D., Zhai, D., Wang, G., Xu, N., Yang, M., Song, Y., Zheng, G., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.670854 · Cited by 10 · see citing works

Role of C-mannosylation in the secretion of mindin

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Dissecting the cellular reprogramming and tumor microenvironment in left- and right-sided Colorectal Cancer by single cell RNA sequencing

Hu, C., Huang, X., Chen, J., Liang, W., Yang, K., Jiang, H., Yang, K., Ou, Q. Z., Li, X., & Zhang, Y. (2024) · Translational research · doi:10.1016/j.trsl.2024.12.002 · Cited by 8 · see citing works

Comprehensive analysis of the oncogenic and immunological role of SPON2 in human tumors

Tang, J., Huang, Q. Y., Li, X., & Gu, S. (2023) · Medicine · doi:10.1097/md.0000000000035122 · Cited by 8 · see citing works

MINDIN secretion by prostate tumors induces premetastatic changes in bone via β-catenin

Ardura, J. A., Álvarez‐Carrión, L., Gutiérrez-Rojas, I., Friedman, P. A., Gortázar, A. R., & Alonso, V. (2020) · Endocrine Related Cancer · doi:10.1530/erc-20-0116 · Cited by 8 · see citing works

Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung DiseasesPreprint

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CD8+ TEMRAs in severe asthma associate with asthma symptom duration and escape proliferation arrest

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GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand

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Extracellular Matrix Protein Mindin is Required for the Complete Allergic Response to Fungal-Associated Proteinase

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Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization

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The Therapeutic Potential of I-Domain Integrins

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Mindin is essential for cutaneous fibrogenesis in a new mouse model of systemic sclerosisPreprint

Rana, I., Kataria, S., Tan, T. L., Hajam, E. Y., Kashyap, D., Saha, D., Ajnabi, J., Paul, S., Jayappa, S., Ananthan, A. S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.26.477822 · Cited by 7 · see citing works

Systematic identification of key basement membrane related genes as potential new biomarkers in Alzheimer's disease

Lin, J., Chen, J., & Huang, C. B. (2023) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2023.108094 · Cited by 6 · see citing works

MINDIN Exerts Protumorigenic Actions on Primary Prostate Tumors via Downregulation of the Scaffold Protein NHERF-1

Álvarez‐Carrión, L., Gutiérrez-Rojas, I., Rodríguez-Ramos, M. R., Ardura, J. A., & Alonso, V. (2021) · Cancers · doi:10.3390/cancers13030436 · Cited by 6 · see citing works

Overexpression of Spondin-2 Is Associated with Recurrence-Free Survival in Patients with Localized Clear Cell Renal Cell Carcinoma

Ma, H., Yu, M., Wu, C., Huang, H., Li, Y., Zhang, P., Huang, J., Cheng, L., Feng, G. L., & Li, G. (2020) · Disease Markers · doi:10.1155/2020/5074239 · Cited by 5 · see citing works

Proceedings of the 26th European Paediatric Rheumatology Congress: part 1

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In situ assessment of Mindin as a biomarker of podocyte lesions in diabetic nephropathy

Martins, A. L. M. D. S., Bernardes, A. B., Ferreira, V. A., Wanderley, D. C., Araújo, S. D. A., Neto, J. R. D. C., da Silva, C. A., Lira, R. C. P., Araújo, L. S., dos Reis, M. A., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0284789 · Cited by 4 · see citing works

The Comparison Spondin 2 Levels in Primary Glomerular Diseases

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CD47 contributes to neutrophil recruitment (146.2)

Azcutia, V., Croce, K., Herter, J. M., Newton, G. A., Mayadas, T. N., & Luscinskas, F. W. (2014) · The FASEB Journal · doi:10.1096/fasebj.28.1_supplement.146.2

Extracellular Matrix Lumican Deposited on the Surface of Neutrophils Promotes Migration by Binding to β2 Integrin

Lee, S., Bowrin, K., Hamad, A. R. A., & Chakravarti, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.026229 · Cited by 83 · see citing works

Functions of integrin receptors in extravascular neutrophil migration and respiratory burst

Werr, J. (2000) · Figshare

Integrin-dependent neutrophil migration in extravascular tissue

Lindbom, L., & Werr, J. (2002) · Seminars in Immunology · doi:10.1006/smim.2001.0348 · Cited by 100 · see citing works

Integrin α2β1 (VLA-2) is a principal receptor used by neutrophils for locomotion in extravascular tissue

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