The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes
Open accessAbstract
In this multicenter retrospective study, the outcomes of 836 patients with myelodysplastic syndrome (MDS) who underwent transplantation with a human leukocyte antigen (HLA)-identical sibling donor were analyzed according to 2 types of conditioning: reduced-intensity conditioning (RIC) in 215 patients, and standard myeloablative (or high-dose) conditioning (SMC) in 621 patients. In multivariate analysis, the 3-year relapse rate was significantly increased after RIC (hazard ratio [HR], 1.64; 95% confidence interval [95% CI], 1.2-2.2; P = .001), but the 3-year nonrelapse mortality (NRM) rate was decreased in the RIC group (HR, 0.61; 95% CI, 0.41-0.91; P = .015). The 3-year probabilities of progression-free and overall survivals were similar in both groups (39% after SMC vs 33% in RIC; multivariate P = .9; and 45% vs 41%, respectively; P = .8). In conclusion, the lower 3-year NRM after RIC is encouraging, since these patients were older (age > 50 years in 73% RIC vs 28% in SMC, P < .001) and had more adverse pretransplantation variables. However, based on the higher risk of relapse, patients with no contraindications for SMC should not receive RIC outside of prospective randomized trials, which are needed to establish the position of RIC-based transplantation in the treatment of patients with MDS.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1994 Consensus Conference on Acute GVHD Grading.
Przepiorka, D., Weisdorf, D., Martin, P., Hg, K., Beatty, P., Hows, J., & Thomas, E. D. (1995) · PubMed · Cited by 5,037
International scoring system for evaluating prognosis in myelodysplastic syndromes
Greenberg, P., Cox, C., LeBeau, M. M., Fenaux, P., Morel, P., Sanz, G., Sanz, M., Vallespi, T., Hamblin, T., Oscier, D., et al. (1997) · Blood · doi:10.1182/blood.v89.6.2079 · Cited by 4,427
Clift, R., Buckner, C., Appelbaum, F., Bearman, S., Petersen, F., Fisher, L., Anasetti, C., Beatty, P., Bensinger, W., & Doney, K. (1990) · Blood · doi:10.1182/blood.v76.9.1867.1867 · Cited by 585
Chakraverty, R., Peggs, K., Chopra, R., Milligan, D. W., Kottaridis, P. D., Verfuerth, S., Geary, J., Thuraisundaram, D., Branson, K., Chakrabarti, S., et al. (2002) · Blood · doi:10.1182/blood.v99.3.1071 · Cited by 345
Klein, J., Rizzo, J., Zhang, M.-J., & Keiding, N. (2001) · Bone Marrow Transplantation · doi:10.1038/sj.bmt.1703260 · Cited by 278
Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia.
Sierra, J., Pérez, W. S., Rozmán, C., Carreras, E., Klein, J. P., Rizzo, J. D., Davies, S. M., Lazarus, H. M., Bredeson, C., Marks, D. I., et al. (2002) · PubMed · Cited by 269
De Witte, T., Hermans, J., Vossen, J., Bacigalupo, A., Meloni, G., Jacobsen, N., Ruutu, T., Ljungman, P., Gratwohl, A., Runde, V., et al. (2000) · British Journal of Haematology · doi:10.1046/j.1365-2141.2000.02200.x · Cited by 251
Pérez-Simón, J. A., Kottaridis, P. D., Martino, R., Craddock, C., Caballero, D., Chopra, R., Garcı́a-Conde, J., Milligan, D. W., Schey, S., Urbano-Ispizua, A., et al. (2002) · Blood · doi:10.1182/blood-2002-03-0701 · Cited by 245
Self-citationHo, A. Y. L., Pagliuca, A., Kenyon, M., Parker, J. E., Mijovic, A., Devereux, S., & Mufti, G. J. (2004) · Blood · doi:10.1182/blood-2003-12-4207 · Cited by 203
Cited by
Scott, B. L., Pasquini, M. C., Logan, B. R., Wu, J., Devine, S. M., Porter, D. L., Maziarz, R. T., Warlick, E. D., Fernandez, H. F., Alyea, E. P., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.70.7091 · Cited by 667
Sureda, A., Bader, P., Cesaro, S., Dreger, P., Duarte, R. F., Dufour, C., Falkenburg, J. H. F., Farge-Bancel, D., Gennery, A., Kröger, N., et al. (2015) · Bone Marrow Transplantation · doi:10.1038/bmt.2015.6 · Cited by 337
Schmid, C., Labopin, M., Nagler, A., Niederwieser, D., Castagna, L., Tabrizi, R., Stadler, M., Kuball, J., Cornelissen, J., Vorlicek, J., et al. (2012) · Blood · doi:10.1182/blood-2011-08-375840 · Cited by 300
Metadata
- Authors
- Martino, R.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2006-08-01
- Volume
- 108
- Issue
- 3
- Pages
- 836-846
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2103628120
- Cited by
- 364
- References
- 19
- FWCI
- 18.37
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes. https://app.cochat.ai/papers/10.1182/blood-2005-11-4503
- The paper
- Martino, R. (2006). Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes. Blood. https://doi.org/10.1182/blood-2005-11-4503
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
