The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15
Open accessAbstract
Key Points: The frequency of CD8+CD45RA+CCR7+ cells, a subset closest to T-memory stem cells, correlates with CAR–T-cell expansion in lymphoma patients. IL-7 and IL-15 increase the frequency of CD8+CD45RA+CCR7+ cells during the ex vivo expansion of CAR+ T cells.
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Cites
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
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Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
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A human memory T cell subset with stem cell–like properties
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“The expression of CD45RO within a CD8(1) CD45RA(1)CCR7(1) T-cell compartment places this subset in a differentiation stage that is closely related to the previously described “T-memory stem cells” that are phenotypically similar but lack CD45RO expression.(16,26,27) CD95, another maker associated with “T-memory stem c…”
BackgroundAdoptive immunotherapy for cancer: harnessing the T cell response
Restifo, N. P., Dudley, M. E., & Rosenberg, S. A. (2012) · Nature Reviews Immunology · doi:10.1038/nri3191 · Cited by 1,688
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
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Self-citation
Cited by
Long-term outcomes following CAR T cell therapy: what we know so far
Cappell, K. M., & Kochenderfer, J. N. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00754-1 · Cited by 1,382
CAR immune cells: design principles, resistance and the next generation
Labanieh, L., & Mackall, C. L. (2023) · Nature · doi:10.1038/s41586-023-05707-3 · Cited by 658
Kochenderfer, J. N., Somerville, R. P. T., Lu, T., Shi, V., Bot, A., Rossi, J., Xue, A., Goff, S. L., Yang, J. C., Sherry, R. M., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.71.3024 · Cited by 569
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma
Del Bufalo, F., De Angelis, B., Caruana, I., Del Baldo, G., De Ioris, M. A., Serra, A., Mastronuzzi, A., Cefalo, M. G., Pagliara, D., Amicucci, M., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2210859 · Cited by 561
Hartmann, J., Schüßler‐Lenz, M., Bondanza, A., & Buchholz, C. J. (2017) · EMBO Molecular Medicine · doi:10.15252/emmm.201607485 · Cited by 532
Metadata
- Authors
- Xu, Y., Zhang, M., Ramos, C. A., Durett, A., Liu, E., Dakhova, O., Liu, H., Creighton, C. J., Gee, A. P., Heslop, H. E., Rooney, C. M., Savoldo, B., & Dotti, G.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2014-06-12
- Volume
- 123
- Issue
- 24
- Pages
- 3750-3759
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1982795546
- Cited by
- 744
- References
- 36
- FWCI
- 15.51
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. https://app.cochat.ai/papers/10.1182/blood-2014-01-552174
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- Xu, Y., Zhang, M., Ramos, C. A., Durett, A., Liu, E., Dakhova, O., Liu, H., Creighton, C. J., Gee, A. P., Heslop, H. E., Rooney, C. M., Savoldo, B., & Dotti, G. (2014). Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. Blood. https://doi.org/10.1182/blood-2014-01-552174
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
