The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma
Open accessAbstract
Key Points: Rd continuous significantly extended OS compared with MPT and resulted in comparable OS to that with Rd18 in patients with multiple myeloma. Patients achieving complete or very good partial response with Rd benefited greatly from continuous vs fixed treatment in terms of PFS.
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“Lenalidomide plus dexamethasone is a standard treatment for patients with newly diagnosed multiple myeloma who are ineligible for autologous stem-cell transplantation.”
From Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma (2019) · cites this paper as [17]
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Cites
International uniform response criteria for multiple myeloma
Durie, B. G. M., Harousseau, J.-L., Miguel, J. S., Bladé, J., Barlogie, B., Anderson, K., Gertz, M., Dimopoulos, M., Westin, J., Sonneveld, P., et al. (2006) · Leukemia · doi:10.1038/sj.leu.2404284 · Cited by 2,632
Self-citationLenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
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The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
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Self-citationCarfilzomib, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma
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Self-citationLenalidomide plus Dexamethasone for Relapsed Multiple Myeloma in North America
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Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma
Facon, T., Kumar, S., Plesner, T., Orlowski, R. Z., Moreau, P., Bahlis, N., Basu, S., Nahi, H., Hulin, C., Quach, H., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1817249 · Cited by 1,045
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Metadata
- Authors
- Facon, T., Dimopoulos, M. A., Dispenzieri, A., Catalano, J. V., Belch, A., Cavo, M., Pinto, A., Weisel, K., Ludwig, H., Bahlis, N. J., Banos, A., Tiab, M., Delforge, M., Cavenagh, J. D., Geraldes, C., Lee, J.-J., Chen, C., Oriol, A., De La Rubia, J., White, D., Binder, D., Lu, J., Anderson, K. C., Moreau, P., Attal, M., Perrot, A., Arnulf, B., Qiu, L., Roussel, M., Boyle, E., Manier, S., Mohty, M., Avet-Loiseau, H., Leleu, X., Ervin-Haynes, A., Chen, G., Houck, V., Benboubker, L., & Hulin, C.
- Affiliations
- Hôpital Claude Huriez (FR)
- National and Kapodistrian University of Athens (GR)
- Mayo Clinic (US)
- Frankston Hospital (AU)
- Cross Cancer Institute (CA)
- Seragnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy;
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- University of Tübingen (DE)
- Wilhelminen Hospital (AT)
- University of Calgary (CA)
- Centre Hospitalier de la Côte Basque (FR)
- Department of Hematology, University Hospital, La Roche Sur Yon, France;
- Universitair Ziekenhuis Leuven (BE)
- National Health Service (GB)
- Unidade Local de Saúde de Coimbra (PT)
- Chonnam National University Hwasun Hospital (KR)
- Princess Margaret Cancer Centre (CA)
- Josep Carreras Leukaemia Research Institute (ES)
- Hospital Dr. Peset, Valencia, Spain;
- Queen Elizabeth II Health Sciences Centre (CA)
- Kantonsspital Winterthur (CH)
- Peking University People's Hospital (CN)
- Dana-Farber Cancer Institute (US)
- Université de Nantes (FR)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Hôpital Saint-Louis (FR)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Hôpital Saint-Antoine (FR)
- Unite de Genomique du Myelome, Centre Hospitalier Universitaire Rangueil, Toulouse, France;
- Inserm (FR)
- Celgene (United States) (US)
- Centre Hospitalier Universitaire de Tours (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- ORCID
- Facon, Thierry
- Dimopoulos, Meletios A.
- Dispenzieri, Angela
- Belch, Andrew
- Weisel, Katja
- Ludwig, Heinz
- Bahlis, Nizar J.
- Banos, Anne
- Delforge, Michel
- Geraldes, Catarina
- Lee, Je-Jung
- Chen, Christine
- Oriol, Albert
- White, Darrell
- Lu, Jin
- Anderson, Kenneth C.
- Moreau, Philippe
- Attal, Michel
- Perrot, Aurore
- Arnulf, Bertrand
- Qiu, Lugui
- Roussel, Murielle
- Boyle, Eileen
- Manier, Salomon
- Mohty, Mohamad
- Leleu, Xavier
- Chen, Guang
- Benboubker, Lotfi
- Hulin, Cyrille
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2018-01-18
- Volume
- 131
- Issue
- 3
- Pages
- 301-310
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- PMC
- PMC5774211
- OpenAlex
- W2769593282
- Cited by
- 271
- References
- 23
- Citations by year
- 2026: 8 · 2025: 22 · 2024: 15 · 2023: 31 · 2022: 36 · 2021: 43 · 2020: 48 · 2019: 40 · 2018: 27
- FWCI
- 24.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Blood (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- Funders
- Celgene
- National Cancer Institute (P50CA186781)
- Topics
- Health Sciences › Medicine › Hematology › Multiple Myeloma Research and Treatments
- Health Sciences › Medicine › Oncology › Bone health and treatments
- Health Sciences › Medicine › Hematology › Chronic Lymphocytic Leukemia Research
- Keywords
- multiple myeloma, transplant-ineligible multiple myeloma, lenalidomide, bortezomib, second-line therapy, survival outcomes, time to next treatment, complete response, secondary malignancies, FIRST trial
- MeSH terms
- Progression-Free Survival, Antineoplastic Agents, Humans, Multiple Myeloma, Survival Analysis, Treatment Outcome
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