The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1)
Abstract
A variant subline (KG-1a) of the human acute myelogenous leukemia (AML) cell line (KG-1) has been isolated. The cells retain the same constitutive markers as the parent line, including HLA antigens, isoenzymes, and karyotype. The cells from the subline are morphologically and histochemically undifferentiated blast cells, while the parent cells and several of its clones are at the myeloblast and promyelocyte stages of development. The variant cells do not respond to colony-stimulating factor (CSF), and they do not express the human la antigen, nor a recently characterized AML antigen. The parent KG-1 cells are stimulated to proliferate in the presence of CSF and the cells express the la and AML antigen. Variant AML cell lines, such as KG-1a, will be useful in vitro models for investigating cellular response to CSF and for studying antigen expression in leukemic cells.
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Cited by
Ramasamy, R., Lam, E. W.-F., Soeiro, I., Tisato, V, Bonnet, D., & Dazzi, F. (2007) · Leukemia · doi:10.1038/sj.leu.2404489 · Cited by 404
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Koeffler, H., & Golde, D. (1980) · Blood · doi:10.1182/blood.v56.3.344.344 · Cited by 349
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Lentiviral vectors for enhanced gene expression in human hematopoietic cells
Ramezani, A., Hawley, T. S., & Hawley, R. G. (2000) · Molecular Therapy · doi:10.1006/mthe.2000.0190 · Cited by 217
St. Louis, D. C., Woodcock, J. B., Fransozo, G., Blair, P. J., Carlson, L. M., Murillo, M., Wells, M. R., Williams, A. J., Smoot, D. S., Kaushal, S., et al. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.6.3237 · Cited by 87
Metadata
- Authors
- Koeffler, H., Billing, R., Lusis, A., Sparkes, R., & Golde, D.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1980-08-01
- Volume
- 56
- Issue
- 2
- Pages
- 265-273
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2293469257
- Cited by
- 266
- References
- 24
- FWCI
- 4.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Koeffler, H., Billing, R., Lusis, A., Sparkes, R., & Golde, D. (1980). An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1). Blood. https://doi.org/10.1182/blood.v56.2.265.265
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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