The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors
Open accessAbstract
A monoclonal antibody, 12–8, prepared against KG-1a cells, recognizes an approximately 115-kd cell surface antigen and reacts with 3% to 4% of bone marrow cells, including most of the blast cells. The antigen is not expressed on peripheral blood cells. Marrow cells expressing 12–8 collected by fluorescence-activated cell sorting contained nearly all of the unipotent (CFU-GM, BFU-E) and multipotent (CFU-MIX) colony- forming cells. The isolated 12–8 positive marrow population also contained precursors of these colony-forming cells. In a two-stage long- term marrow culture system employing irradiated allogeneic marrow adherent cells, 12–8 positive cells produced both unipotent and multipotent colony-forming cells for ten weeks. Moreover, the output of colony forming cells substantially exceeded the input. Antibody 12–8 appears useful for analysis and possibly enrichment of hematopoietic progenitor cells that include colony-forming cell precursors.
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Cites
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Andrews, R., Torok-Storb, B., & Bernstein, I. (1983) · Blood · doi:10.1182/blood.v62.1.124.124 · Cited by 257
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Fitchen, J. H., Fevre, C. L., Ferrone, S., et al. (1982) · Blood · doi:10.1182/blood.v59.1.188.188 · Cited by 68
Cited by
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
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Simmons, P., Masinovsky, B., Longenecker, B., Berenson, R., Torok-Storb, B., & Gallatin, W. (1992) · Blood · doi:10.1182/blood.v80.2.388.388 · Cited by 422
Andrews, R. G., Singer, J. W., & Bernstein, I. D. (1989) · The Journal of experimental medicine · doi:10.1084/jem.169.5.1721 · Cited by 422
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Metadata
- Authors
- Andrews, R., Singer, J., & Bernstein, I.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1986-03-01
- Volume
- 67
- Issue
- 3
- Pages
- 842-845
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1503883962
- Cited by
- 372
- References
- 7
- FWCI
- 6.70
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors. https://app.cochat.ai/papers/10.1182/blood.v67.3.842.842
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- Andrews, R., Singer, J., & Bernstein, I. (1986). Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors. Blood. https://doi.org/10.1182/blood.v67.3.842.842
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
