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Hemoglobin S gelation and sickle cell disease
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“The rate and extent of polymerization is modified by the erythrocyte HbF concentration. 2”
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Metadata
- Authors
- Eaton, W., & Hofrichter, J.
- Affiliations
- National Institutes of Health (US)
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1987-11-01
- Volume
- 70
- Issue
- 5
- Pages
- 1245-1266
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1919238100
- Cited by
- 425
- References
- 143
- Citations by year
- 2026: 10 · 2025: 2 · 2024: 9 · 2023: 13 · 2022: 12 · 2021: 16 · 2020: 11 · 2019: 23 · 2018: 18 · 2017: 16 · 2016: 15 · 2015: 8 · 2014: 8 · 2013: 18 · 2012: 14
- FWCI
- 12.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Blood (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Hemoglobin structure and function
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Keywords
- hemoglobin S, sickle cell disease, hemoglobin polymerization, vaso-occlusive crisis
- MeSH terms
- Anemia, Sickle Cell, Gels, Hemoglobin, Sickle, Humans, Oxyhemoglobins, Protein Conformation
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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