The DOI matches its Crossref record; 142 of the 143 references it cites were found in a registry or an index.
Hemoglobin S gelation and sickle cell disease
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“The rate and extent of polymerization is modified by the erythrocyte HbF concentration. 2”
From Fetal hemoglobin in sickle cell anemia (2020) · cites this paper as [2]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.
Monod, J., Wyman, J., & Changeux, J. (1965) · Journal of Molecular Biology · doi:10.1016/s0022-2836(65)80285-6 · Cited by 7,681
Krogh, A. (1919) · The Journal of Physiology · doi:10.1113/jphysiol.1919.sp001839 · Cited by 1,433
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
Platt, O., Orkin, S. H., Dover, G., Beardsley, G. P., Miller, B. A., & Nathan, D. G. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111464 · Cited by 532
Hofrichter, J., Ross, P. D., & Eaton, W. A. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.12.4864 · Cited by 520
Self-citationErythrocyte Adherence to Endothelium in Sickle-Cell Anemia
Hebbel, R. P., Boogaerts, M., Eaton, J. W., & Steinberg, M. H. (1980) · New England Journal of Medicine · doi:10.1056/nejm198005013021803 · Cited by 518
Kinetics of sickle hemoglobin polymerization
Ferrone, F. A., Hofrichter, J., & Eaton, W. A. (1985) · Journal of Molecular Biology · doi:10.1016/0022-2836(85)90175-5 · Cited by 505
Self-citationAbnormal Adherence of Sickle Erythrocytes to Cultured Vascular Endothelium
Hebbel, R. P., Yamada, O., Moldow, C. F., Jacob, H. S., White, J. G., & Eaton, J. W. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109646 · Cited by 421
Abnormal rheology of oxygenated blood in sickle cell anemia
Chien, S., Usami, S., & Bertles, J. F. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106273 · Cited by 358
Is there a threshold level of fetal hemoglobin that ameliorates morbidity in sickle cell anemia?
Powars, D., Weiss, J., Chan, L., & Schroeder, W. (1984) · Blood · doi:10.1182/blood.v63.4.921.921 · Cited by 314
Hemoglobin as a receptor of drugs and peptides: x-ray studies of the stereochemistry of binding
Perutz, M. F., Fermi, G., Abraham, D. J., Poyart, C., & Bursaux, E. (1986) · Journal of the American Chemical Society · doi:10.1021/ja00265a036 · Cited by 299
Cited by
Sorted by citations
Functional significance of cell volume regulatory mechanisms
LANG, F., BUSCH, G. L., RITTER, M., VÖLKL, H., WALDEGGER, S., GULBINS, E., & HÄUSSINGER, D. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.1.247 · Cited by 1,891
Pathogenesis and Treatment of Sickle Cell Disease
Bunn, H. F. (1997) · New England Journal of Medicine · doi:10.1056/nejm199709113371107 · Cited by 1,154
A new era for understanding amyloid structures and disease
Iadanza, M. G., Jackson, M. P., Hewitt, E. W., Ranson, N. A., & Radford, S. E. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0060-8 · Cited by 1,002
Sickle Cell Hemoglobin Polymerization
Eaton, W. A., & Hofrichter, J. (1990) · Advances in protein chemistry · doi:10.1016/s0065-3233(08)60287-9 · Cited by 623
Self-citationFetal hemoglobin in sickle cell anemia
Akinsheye, I., Alsultan, A., Solovieff, N., Ngo, D., Baldwin, C. T., Sebastiani, P., Chui, D. H. K., & Steinberg, M. H. (2011) · Blood · doi:10.1182/blood-2011-03-325258 · Cited by 553
Membrane Mechanisms and Intracellular Signalling in Cell Volume Regulation
Hoffmann, E. K., & Dunham, P. B. (1995) · International review of cytology · doi:10.1016/s0074-7696(08)62498-5 · Cited by 469
Brugnara, C., Franceschi, L. D., & Alper, S. L. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116597 · Cited by 359
Chronic Renal Failure in Sickle Cell Disease: Risk Factors, Clinical Course, and Mortality
Powars, D. R., Elliott-Mills, D. D., Chan, L. S., Niland, J. C., Hiti, A. L., Opas, L. M., & Johnson, C. S. (1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-115-8-614 · Cited by 357
Kato, G. J., Hebbel, R. P., Steinberg, M. H., & Gladwin, M. T. (2009) · American Journal of Hematology · doi:10.1002/ajh.21475 · Cited by 349
Hydroxyurea and Sickle Cell Anemia Clinical Utility of a Myelosuppressive “Switching” Agent
Charache, S., Barton, F. B., Moore, R. D., Terrin, M. L., Steinberg, M. H., Dover, G. J., Ballas, S. K., McMahon, R. P., Castro, O. L., & Orringer, E. P. (1996) · Medicine · doi:10.1097/00005792-199611000-00002 · Cited by 335
Correction of sickle cell disease by homologous recombination in embryonic stem cells
Wu, L.-C., Sun, C., Ryan, T. M., Pawlik, K. M., Ren, J., & Townes, T. M. (2006) · Blood · doi:10.1182/blood-2006-02-004812 · Cited by 327
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology
Hebbel, R. (1991) · Blood · doi:10.1182/blood.v77.2.214.bloodjournal772214 · Cited by 365
Knockout-Transgenic Mouse Model of Sickle Cell Disease
Ryan, T. M., Ciavatta, D. J., & Townes, T. M. (1997) · Science · doi:10.1126/science.278.5339.873 · Cited by 300
The functional nitrite reductase activity of the heme-globins
Gladwin, M. T., & Kim-Shapiro, D. B. (2008) · Blood · doi:10.1182/blood-2008-01-115261 · Cited by 293
Swerlick, R., Eckman, J., Kumar, A. F., Jeitler, M., & Wick, T. (1993) · Blood · doi:10.1182/blood.v82.6.1891.1891 · Cited by 275
Fetal hemoglobin in sickle cell anemia: a glass half full?
Steinberg, M. H., Chui, D. H. K., Dover, G. J., Sebastiani, P., & Alsultan, A. (2014) · Blood · doi:10.1182/blood-2013-09-528067 · Cited by 267
Treating sickle cell disease by targeting HbS polymerization
Eaton, W. A., & Bunn, H. F. (2017) · Blood · doi:10.1182/blood-2017-02-765891 · Cited by 255
Self-citationVascular occlusion in sickle cell disease: current concepts and unanswered questions
Francis, R. J., & Johnson, C. (1991) · Blood · doi:10.1182/blood.v77.7.1405.bloodjournal7771405 · Cited by 240
Brugnara, C., Gee, B., Armsby, C. C., Kurth, S., Sakamoto, M., Rifai, N., Alper, S. L., & Platt, O. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118537 · Cited by 231
Rails and anchors: guiding and trapping droplet microreactors in two dimensions
Abbyad, P., Dangla, R., Alexandrou, A., & Baroud, C. N. (2010) · Lab on a Chip · doi:10.1039/c0lc00104j · Cited by 225
Delay Time of Hemoglobin S Polymerization Prevents Most Cells from Sickling in Vivo
Mozzarelli, A., Hofrichter, J., & Eaton, W. A. (1987) · Science · doi:10.1126/science.3603036 · Cited by 222
Self-citationSickle Red Cell–Endothelium Interactions
KAUL, D. K., FINNEGAN, E., & BARABINO, G. A. (2009) · Microcirculation · doi:10.1080/10739680802279394 · Cited by 208
Stocker, J. W., Franceschi, L. D., McNaughton-Smith, G. A., Corrocher, R., Beuzard, Y., & Brugnara, C. (2003) · Blood · doi:10.1182/blood-2002-05-1433 · Cited by 205
Levasseur, D. N., Ryan, T. M., Pawlik, K. M., & Townes, T. M. (2003) · Blood · doi:10.1182/blood-2003-04-1251 · Cited by 199
Treatment of Sickle Cell Anemia with Hydroxyurea and Erythropoietin
Goldberg, M. A., Brugnara, C., Dover, G. J., Schapira, L., Charache, S., & Bunn, H. F. (1990) · New England Journal of Medicine · doi:10.1056/nejm199008093230602 · Cited by 193
A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy
Bridges, K., Barabino, G., Brugnara, C., Cho, M., Christoph, G., Dover, G., Ewenstein, B., Golan, D., Guttmann, C., Hofrichter, J., et al. (1996) · Blood · doi:10.1182/blood.v88.12.4701.bloodjournal88124701 · Cited by 184
Self-citationSupersaturation is a major driving force for protein aggregation in neurodegenerative diseases
Ciryam, P., Kundra, R., Morimoto, R. I., Dobson, C. M., & Vendruscolo, M. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2014.12.004 · Cited by 175
Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease.
Franceschi, L. D., Bachir, D., Galactéros, F., Tchernia, G., Cynober, T., Alper, S. L., Platt, O., Beuzard, Y., & Brugnara, C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119713 · Cited by 167
Chang, K.-H., Smith, S. E., Sullivan, T., Chen, K., Zhou, Q., West, J. A., Liu, M., Liu, Y., Vieira, B. F., Sun, C., et al. (2017) · Molecular Therapy - Methods & Clinical Development · doi:10.1016/j.omtm.2016.12.009 · Cited by 155
Sickle Cell Disease and Anesthesia
Firth, P. G., Head, C. A., & Warltier, D. C. (2004) · Anesthesiology · doi:10.1097/00000542-200409000-00027 · Cited by 157
Life-Threatening Infectious Complications in Sickle Cell Disease: A Concise Narrative Review
Ochocinski, D., Dalal, M., Black, L. V., Carr, S. B., Lew, J., Sullivan, K., & Kissoon, N. “. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.00038 · Cited by 162
The pathophysiology of vascular obstruction in the sickle syndromes
Kaul, D. K. (1996) · Blood Reviews · doi:10.1016/s0268-960x(96)90018-1 · Cited by 154
Newer Aspects of the Pathophysiology of Sickle Cell Disease Vaso-Occlusion
Conran, N., Franco‐Penteado, C. F., & Costa, F. F. (2009) · Hemoglobin · doi:10.1080/03630260802625709 · Cited by 155
Fabry, M. E., & Kaul, D. K. (1991) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(18)30421-0 · Cited by 144
Franceschi, L. D., Saadane, N., Trudel, M., Alper, S. L., Brugnara, C., & Beuzard, Y. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117149 · Cited by 142
Head, C. A., Brugnara, C., Martinez-Ruiz, R., Kacmarek, R. M., Bridges, K. R., Kuter, D. J., Bloch, K. D., & Zapol, W. M. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119631 · Cited by 138
Fetal hemoglobin in sickle cell anemia
Steinberg, M. H. (2020) · Blood · doi:10.1182/blood.2020007645 · Cited by 136
Disorders of erythrocyte hydration
Gallagher, P. G. (2017) · Blood · doi:10.1182/blood-2017-04-590810 · Cited by 144
Sickle‐cell haemoglobin polymerization: is it the primary pathogenic event of sickle‐cell anaemia?
Vekilov, P. G. (2007) · British Journal of Haematology · doi:10.1111/j.1365-2141.2007.06794.x · Cited by 132
Human Sickle Hemoglobin in Transgenic Mice
Ryan, T. M., Townes, T. M., Reilly, M. P., Asakura, T., Palmiter, R. D., Brinster, R. L., & Behringer, R. R. (1990) · Science · doi:10.1126/science.2154033 · Cited by 130
Malaria and red cell genetic defects
Nagel, R. L., & Roth, E. J. (1989) · Blood · doi:10.1182/blood.v74.4.1213.1213 · Cited by 128
Insight into the complex pathophysiology of sickle cell anaemia and possible treatment
Piccin, A., Murphy, C., Eakins, E., Rondinelli, M. B., Daves, M., Vecchiato, C., Wolf, D. G. F., Mahon, C. M., & Smith, O. P. (2019) · European Journal Of Haematology · doi:10.1111/ejh.13212 · Cited by 134
Sickle Red Cell Microrheology and Sickle Blood Rheology
Ballas, S. K., & Mohandas, N. (2004) · Microcirculation · doi:10.1080/10739680490279410 · Cited by 123
Oxygen-Sensitive Membrane Transporters in Vertebrate Red Cells
Gibson, J. S., Cossins, A. R., & Ellory, J. C. (2000) · Journal of Experimental Biology · doi:10.1242/jeb.203.9.1395 · Cited by 123
Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis
Du, E., Diez-Silva, M., Kato, G. J., Dao, M., & Suresh, S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424111112 · Cited by 120
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease
Wood, D. K., Soriano, A., Mahadevan, L., Higgins, J. M., & Bhatia, S. N. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3002738 · Cited by 122
Metastable Mesoscopic Clusters in Solutions of Sickle-Cell Hemoglobin
Pan, W., Galkin, O., Filobelo, L. F., Nagel, R. L., & Vekilov, P. G. (2006) · Biophysical Journal · doi:10.1529/biophysj.106.094854 · Cited by 119
Gene therapy for sickle cell disease: An update
Demirci, S., Uchida, N., & Tisdale, J. F. (2018) · Cytotherapy · doi:10.1016/j.jcyt.2018.04.003 · Cited by 126
Evolution of allosteric models for hemoglobin
Eaton, W. A., Henry, E. R., Hofrichter, J., Bettati, S., Viappiani, C., & Mozzarelli, A. (2007) · IUBMB Life · doi:10.1080/15216540701272380 · Cited by 114
Self-citationThe Acute Chest Syndrome of Sickle Cell Disease
Platt, O. S. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006223422510 · Cited by 112
β-globin gene transfer to human bone marrow for sickle cell disease
Romero, Z. G., Urbinati, F., Geiger, S., Cooper, A. R., Wherley, J., Kaufman, M. L., Hollis, R. P., de Assín, R. R., Senadheera, S., Sahagian, A., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci67930 · Cited by 112
Pathophysiology and therapy for haemoglobinopathies; Part I: sickle cell disease
Madigan, C., & Malik, P. (2006) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399406010659 · Cited by 111
CRISPR/Cas9 gene editing for curing sickle cell disease
Park, S. H., & Bao, G. (2021) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2021.103060 · Cited by 118
ßs-Gene-Cluster Haplotypes in Sickle Cell Anemia: Clinical and Hematologic Features
Powars, D. R. (1991) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(18)30426-x · Cited by 104
Wambebe, C. O. (2001) · Phytomedicine · doi:10.1078/0944-7113-00040 · Cited by 104
Subclinical ischaemic episodes during the steady state of sickle cell anaemia.
Akinola, N. O., Stevens, S. M., FRANKLIN, I. M., Nash, G. B., & Stuart, J. (1992) · Journal of Clinical Pathology · doi:10.1136/jcp.45.10.902 · Cited by 98
Polymerization and Sickle Cell Disease: A Molecular View
Ferrone, F. A. (2004) · Microcirculation · doi:10.1080/10739680490278312 · Cited by 98
The Biophysics of Sickle Cell Hydroxyurea Therapy
Eaton, W. A., & Hofrichter, J. (1995) · Science · doi:10.1126/science.7539154 · Cited by 96
Self-citationUnderstanding the Shape of Sickled Red Cells
Christoph, G. W., Hofrichter, J., & Eaton, W. A. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.051250 · Cited by 97
Self-citationEmerging disease-modifying therapies for sickle cell disease
Carden, M. A., & Little, J. A. (2019) · Haematologica · doi:10.3324/haematol.2018.207357 · Cited by 100
Bauer, H. H., Mueller, M., Goette, J., Merkle, H. P., & Fringeli, U. P. (1994) · Biochemistry · doi:10.1021/bi00206a034 · Cited by 93
Spectral domain optical coherence tomography in patients with sickle cell disease
Mathew, R., Bafiq, R., Ramu, J., Pearce, E., Richardson, M., Drašar, E., Thein, S. L., & Sivaprasad, S. (2015) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2014-305532 · Cited by 91
Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin
Henry, E. R., Metaferia, B. B., Li, Q., Delenko, J., Best, R. B., Glass, K. E., Cellmer, T., Dunkelberger, E. B., Conrey, A. K., Thein, S. L., et al. (2021) · Blood · doi:10.1182/blood.2021012070 · Cited by 91
Self-citationFabry, M. E., Sengupta, A., Suzuka, S. M., Costantini, F. D., Rubin, E. M., Hofrichter, J., Christoph, G. W., Manci, E. A., Culberson, D., & Factor, S. M. (1995) · Blood · doi:10.1182/blood.v86.6.2419.bloodjournal8662419 · Cited by 90
Self-citationHebbel, R. P., Vercellotti, G. M., & Nath, K. A. (2009) · Cardiovascular & Haematological Disorders - Drug Targets · doi:10.2174/1871529x10909040271 · Cited by 91
Genetic epidemiology of the βs gene
Nagel, R. L., & Fleming, A. F. (1992) · Baillière s Clinical Haematology · doi:10.1016/s0950-3536(11)80023-5 · Cited by 87
The Fibrillary Glomerulopathies
Korbet, S. M., Schwartz, M. M., & Lewis, E. J. (1994) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(12)70290-1 · Cited by 87
Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes
Olivieri, O., Vitoux, D., Galactéros, F., Bachir, D., Blouquit, Y., Beuzard, Y., & Brugnara, C. (1992) · Blood · doi:10.1182/blood.v79.3.793.793 · Cited by 86
Gibson, J. S., Speake, P. F., & Ellory, J. C. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.225bi.x · Cited by 84
Management of Pregnancy in Sickle Cell Syndromes
Koshy, M., & Burd, L. I. (1991) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(18)30433-7 · Cited by 82
In Vivo Studies of Sickle Red Blood Cells
Kaul, D. K., & Fabry, M. E. (2004) · Microcirculation · doi:10.1080/10739680490278457 · Cited by 82
Disorders of red cell volume regulation
Gallagher, P. G. (2013) · Current Opinion in Hematology · doi:10.1097/moh.0b013e32835f6870 · Cited by 80
Lande, W. M., Andrews, D., Clark, M., Braham, N., Black, D., Embury, S., & Mentzer, W. C. (1988) · Blood · doi:10.1182/blood.v72.6.2056.2056 · Cited by 78
Bennekou, P., Franceschi, L. D., Pedersen, O., Lian, L., Asakura, T., Evans, G., Brugnara, C., & Christophersen, P. (2001) · Blood · doi:10.1182/blood.v97.5.1451 · Cited by 78
Acid pH induces formation of dense cells in sickle erythrocytes
Brugnara, C., Ha, T. V., & Tosteson, D. C. (1989) · Blood · doi:10.1182/blood.v74.1.487.487 · Cited by 78
Gupta, A., Kirchner, K. A., Nicholson, R., Adams, J. G., Schechter, A. N., Noguchi, C., & Steinberg, M. H. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115521 · Cited by 77
PATHOPHYSIOLOGY OF VASO-OCCLUSION
Ballas, S. K., & Mohandas, N. (1996) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(05)70396-8 · Cited by 76
Sickle Cell Anemia and Major Organ Failure
Powars, D. R. (1990) · Hemoglobin · doi:10.3109/03630269009046967 · Cited by 75
Simultaneous polymerization and adhesion under hypoxia in sickle cell disease
Papageorgiou, D. P., Abidi, S. Z., Chang, H.-Y., Li, X., Kato, G. J., Karniadakis, G. E., Suresh, S., & Dao, M. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1807405115 · Cited by 74
Brugnara, C. (2003) · Journal of Pediatric Hematology/Oncology · doi:10.1097/00043426-200312000-00004 · Cited by 75
Revisiting supersaturation as a factor determining amyloid fibrillation
So, M., Hall, D. R., & Goto, Y. (2016) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2015.11.009 · Cited by 76
Franceschi, L. D., Beuzard, Y., Jouault, H., & Brugnara, C. (1996) · Blood · doi:10.1182/blood.v88.7.2738.bloodjournal8872738 · Cited by 74
Anaesthesia for peculiar cells'a century of sickle cell disease
Firth, P. G. (2005) · British Journal of Anaesthesia · doi:10.1093/bja/aei129 · Cited by 72
3 Sickle cell disease pathophysiology
Noguchi, C. T., Schechter, A. N., & Rodgers, G. P. (1993) · Baillière s Clinical Haematology · doi:10.1016/s0950-3536(05)80066-6 · Cited by 71
Novel Inhibitors of the Gardos Channel for the Treatment of Sickle Cell Disease
McNaughton-Smith, G. A., Burns, J. F., Stocker, J. W., Rigdon, G. C., Creech, C., Arrington, S., Shelton, T. G., & Franceschi, L. D. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm070663s · Cited by 69
Potential of Three Ethnomedicinal Plants as Antisickling Agents
Nurain, I. O., Bewaji, C. O., Johnson, J. S., Davenport, R. D., & Zhang, Y. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b00767 · Cited by 71
Adachi, M., So, M., Sakurai, K., Kardos, J., & Goto, Y. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.648139 · Cited by 67
Recombinant human hemoglobins designed for gene therapy of sickle cell disease.
McCune, S. L., Reilly, M. P., Chomo, M., Asakura, T., & Townes, T. M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.21.9852 · Cited by 65
The initiation and progression of sickle cell nephropathy
Wesson, D. E. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00363.x · Cited by 65
Clinical management of adult sickle-cell disease
Bartolucci, P., & Galactéros, F. (2012) · Current Opinion in Hematology · doi:10.1097/moh.0b013e328351c35f · Cited by 64
Sickling of red blood cells through rapid oxygen exchange in microfluidic drops
Abbyad, P., Tharaux, P., Martin, J. L., Baroud, C. N., & Alexandrou, A. (2010) · Lab on a Chip · doi:10.1039/c004390g · Cited by 61
Jung, J., Byeon, I. L., Wang, Y., King, J. W., & Gronenborn, A. M. (2009) · Biochemistry · doi:10.1021/bi802292q · Cited by 62
Sickle cell states and the anaesthetist
Esseltine, D. W., Baxter, M. R. N., & Bevan, J. C. (1988) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/bf03010861 · Cited by 61
Pathophysiological-Based Approaches to Treatment of Sickle Cell Disease
Steinberg, M. H., & Brugnara, C. (2003) · Annual Review of Medicine · doi:10.1146/annurev.med.54.101601.152439 · Cited by 61
Sickle cell vasoocclusion: Many issues and some answers
Kaul, D. K., & Nagel, R. L. (1993) · Cellular and Molecular Life Sciences · doi:10.1007/bf01928783 · Cited by 60
Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion
Carden, M. A., Fay, M. E., Lu, X., Mannino, R. G., Sakurai, Y., Ciciliano, J. C., Hansen, C. E., Chonat, S., Joiner, C. H., Wood, D. K., et al. (2017) · Blood · doi:10.1182/blood-2017-04-780635 · Cited by 60
A FISIOPATOLOGIA DA ANEMIA FALCIFORME
Manfredini, V., de Castro, S. M., Wagner, S. C., & Benfato, M. D. S. (2013) · Infarma - Ciências Farmacêuticas · Cited by 58
Cox, S. E., Makani, J., Soka, D., L’Esperence, V., Kija, E., Domínguez-Salas, P., Newton, C. R. J. C., Birch, A. A., Prentice, A. M., & Kirkham, F. J. (2014) · British Journal of Haematology · doi:10.1111/bjh.12791 · Cited by 57
Bush, A., Coates, T. D., & Wood, J. C. (2017) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27015 · Cited by 56
Membrane Transport in Sickle Cell Disease
Gibson, J. S., & Ellory, J. C. (2002) · Blood Cells Molecules and Diseases · doi:10.1006/bcmd.2002.0515 · Cited by 55
Metadata
- Authors
- Eaton, W., & Hofrichter, J.
- Affiliations
- National Institutes of Health (US)
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1987-11-01
- Volume
- 70
- Issue
- 5
- Pages
- 1245-1266
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1919238100
- Cited by
- 425
- References
- 143
- Citations by year
- 2026: 10 · 2025: 2 · 2024: 9 · 2023: 13 · 2022: 12 · 2021: 16 · 2020: 11 · 2019: 23 · 2018: 18 · 2017: 16 · 2016: 15 · 2015: 8 · 2014: 8 · 2013: 18 · 2012: 14
- FWCI
- 12.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Blood (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Hemoglobin structure and function
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Keywords
- hemoglobin S, sickle cell disease, hemoglobin polymerization, vaso-occlusive crisis
- MeSH terms
- Anemia, Sickle Cell, Gels, Hemoglobin, Sickle, Humans, Oxyhemoglobins, Protein Conformation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review