STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

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CIS, a Cytokine Inducible SH2 Protein, Is a Target of the JAK-STAT5 Pathway and Modulates STAT5 Activation

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL‐6 signal transduction

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Cytokine‐inducible SH2 protein‐3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N‐terminal kinase inhibitory region as well as SH2 domain

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The Suppressor of Cytokine Signaling (SOCS) 1 and SOCS3 but Not SOCS2 Proteins Inhibit Interferon-mediated Antiviral and Antiproliferative Activities

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Growth Hormone Preferentially Induces the Rapid, Transient Expression of SOCS-3, a Novel Inhibitor of Cytokine Receptor Signaling

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SOCS-3 Is Tyrosine Phosphorylated in Response to Interleukin-2 and Suppresses STAT5 Phosphorylation and Lymphocyte Proliferation

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Autoregulation of pituitary corticotroph SOCS-3 expression: Characterization of the murine SOCS-3 promoter

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Suppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice

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Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma.

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Negative regulators of cytokine signal transduction

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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

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Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.

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Lipopolysaccharide Induces in Macrophages the Synthesis of the Suppressor of Cytokine Signaling 3 and Suppresses Signal Transduction in Response to the Activating Factor IFN-γ

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A Janus Kinase Inhibitor, JAB, Is an Interferon-γ–Inducible Gene and Confers Resistance to Interferons

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Cutting Edge: SOCS-1 Is a Potent Inhibitor of IL-4 Signal Transduction

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Direct Association of STAT3 with the IFNAR-1 Chain of the Human Type I Interferon Receptor

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Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

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Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides

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STAT Signaling in the Pathogenesis and Treatment of Cancer

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CIS Associates with the Interleukin-2 Receptor β Chain and Inhibits Interleukin-2-dependent Signaling

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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides : tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

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Superantigens Are Presented by and Activate Thymocytes from Infants

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T he R ole of S uppressors of C ytokine S ignaling (SOCS) P roteins in R egulation of the I mmune R esponse

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Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

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SOCS regulation of the JAK/STAT signalling pathway

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Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

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The Pathogenesis of Mycosis Fungoides

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Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNα

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In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3

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Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

Nielsen, M., Nissen, M. H., Gerwien, J. G., Zocca, M.-B., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, C., Kaltoft, K., & Ødum, N. (2002) · Blood · doi:10.1182/blood.v99.3.973 · Cited by 67

O18 Molecular crosstalk between PLCγ1 and STAT3 in cutaneous T-cell lymphoma

Campbell, V., Flanagan, C. E., Tosi, I., Jones, C. L., Whittaker, S. J., John, S., & Mitchell, T. J. (2023) · British Journal of Dermatology · doi:10.1093/bjd/ljad174.018

The Suppressor of Cytokine Signaling-3 Gene Is Overexpressed in Human De Novo Follicular Lymphomas and Promotes IL-3-Independent Proliferation of the BaF3 Pro-B Cell Line.

Barrientos, J. C., Rodov, S., Zieske, A. W., & Vanasse, K. G. J. (2004) · Blood · doi:10.1182/blood.v104.11.1107.1107