The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease
Open accessAbstract
Background: von Willebrand disease (VWD) is the most common inherited bleeding disorder known in humans. Accurate and timely diagnosis presents numerous challenges. Objective: These evidence-based guidelines of the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation (NHF), and the World Federation of Hemophilia (WFH) are intended to support patients, clinicians, and other health care professionals in their decisions about VWD diagnosis. Methods: ASH, ISTH, NHF, and WFH established a multidisciplinary guideline panel that included 4 patient representatives and was balanced to minimize potential bias from conflicts of interest. The Outcomes and Implementation Research Unit at the University of Kansas Medical Center (KUMC) supported the guideline-development process, including performing or updating systematic evidence reviews up to 8 January 2020. The panel prioritized clinical questions and outcomes according to their importance for clinicians and patients. The panel used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, including GRADE Evidence-to-Decision frameworks, to assess evidence and make recommendations, which were subsequently subject to public comment. Results: The panel agreed on 11 recommendations. Conclusions: Key recommendations of these guidelines include the role of bleeding-assessment tools in the assessment of patients suspected of VWD, diagnostic assays and laboratory cutoffs for type 1 and type 2 VWD, how to approach a type 1 VWD patient with normalized levels over time, and the role of genetic testing vs phenotypic assays for types 2B and 2N. Future critical research priorities are also identified.
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GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
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“The certainty was categorized into 4 levels: very low (Å◯◯◯), low (ÅÅ◯◯), moderate (ÅÅÅ◯), and high (ÅÅÅÅ).(7,8,29,30,37-39)”
QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
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GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables
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Clinical Practice Guidelines We Can Trust
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GRADE guidelines: 2. Framing the question and deciding on important outcomes
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Self-citationAtkins, D., Eccles, M., Flottorp, S., Guyatt, G. H., Henry, D., Hill, S., Liberati, A., O'Connell, D., Oxman, A. D., Phillips, B., et al. (2004) · BMC Health Services Research · doi:10.1186/1472-6963-4-38 · Cited by 1,235
SADLER, J. E., BUDDE, U., EIKENBOOM, J. C. J., FAVALORO, E. J., HILL, F. G. H., HOLMBERG, L., INGERSLEV, J., LEE, C. A., LILLICRAP, D., MANNUCCI, P. M., et al. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.02146.x · Cited by 1,150
Self-citationThe effect of ABO blood group on the diagnosis of von Willebrand disease
Gill, J., Endres-Brooks, J., Bauer, P., Marks, W. J., & Montgomery, R. (1987) · Blood · doi:10.1182/blood.v69.6.1691.1691 · Cited by 957
Metadata
- Authors
- James, P. D., Connell, N. T., Ameer, B., Di Paola, J., Eikenboom, J., Giraud, N., Haberichter, S., Jacobs-Pratt, V., Konkle, B., McLintock, C., McRae, S., R. Montgomery, R., O’Donnell, J. S., Scappe, N., Sidonio, R., Flood, V. H., Husainat, N., Kalot, M. A., & Mustafa, R. A.
- Venue
- Blood Advances
- Publisher
- American Society of Hematology
- Published
- 2021-01-12
- Volume
- 5
- Issue
- 1
- Pages
- 280-300
- ISSN
- 2473-9529 (ISSN-L)
- 2473-9537
- OpenAlex
- W3121114429
- Cited by
- 586
- References
- 43
- FWCI
- 48.57
- Type
- journal article
- Language
- en
- Open access
- gold
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- James, P. D., Connell, N. T., Ameer, B., Di Paola, J., Eikenboom, J., Giraud, N., Haberichter, S., Jacobs-Pratt, V., Konkle, B., McLintock, C., McRae, S., R. Montgomery, R., O’Donnell, J. S., Scappe, N., Sidonio, R., Flood, V. H., Husainat, N., Kalot, M. A., & Mustafa, R. A. (2021). ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. Blood Advances. https://doi.org/10.1182/bloodadvances.2020003265
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