The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The effect of ABO blood group on the diagnosis of von Willebrand disease
Open accessAbstract
In order to firmly establish a normal range for von Willebrand factor antigen (vWF:Ag), we determined plasma vWF:Ag concentrations in 1,117 volunteer blood donors by quantitative immunoelectrophoresis. The presence of the ABO blood group has a significant influence on vWF:Ag values; individuals with blood group O had the lowest mean vWF:Ag level (74.8 U/dL), followed by group A (105.9 U/dL), then group B (116.9 U/dL), and finally group AB (123.3 U/dL). Multiple regression analysis revealed that age significantly correlated with vWF:Ag levels in each blood group. We then performed reverse ABO typing on stored plasma from 142 patients with the diagnosis of von Willebrand disease (vWd). Of 114 patients with type I vWd, blood group O was found in 88 (77%), group A in 21 (18%), group B in 5 (4%), and group AB in none (0%), whereas the frequency of these blood groups in the normal population is significantly different (45%, 45%, 7% and 3%, respectively) (P less than .001). Patients with type II or III vWd had ABO blood group frequencies that were not different from the expected distribution. There may be a subset of symptomatic vWd patients with decreased concentrations of structurally normal vWf (vWd, type I) on the basis of blood group O. Some individuals of blood group AB with a genetic defect of vWF may have the diagnosis overlooked because vWF levels are elevated due to blood type.
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The factor VIII complex: structure and function
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Genetic analysis of von Willebrand's disease in two large pedigrees: A multivariate approach
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Cited by
BIOCHEMISTRY AND GENETICS OF VON WILLEBRAND FACTOR
Sadler, J. E. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.395 · Cited by 1,363
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ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease
James, P. D., Connell, N. T., Ameer, B., Di Paola, J., Eikenboom, J., Giraud, N., Haberichter, S., Jacobs-Pratt, V., Konkle, B., McLintock, C., et al. (2021) · Blood Advances · doi:10.1182/bloodadvances.2020003265 · Cited by 586
ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?
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Metadata
- Authors
- Gill, J., Endres-Brooks, J., Bauer, P., Marks, W. J., & Montgomery, R.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1987-06-01
- Volume
- 69
- Issue
- 6
- Pages
- 1691-1695
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1618588028
- Cited by
- 957
- References
- 8
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gill, J., Endres-Brooks, J., Bauer, P., Marks, W. J., & Montgomery, R. (1987). The effect of ABO blood group on the diagnosis of von Willebrand disease. Blood. https://doi.org/10.1182/blood.v69.6.1691.1691
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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