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Multidimensional approach to non-cystic fibrosis bronchiectasis: the FACED score
Open accessAbstract
Bronchiectasis is a multidimensional disease and, therefore, its severity or prognosis cannot be adequately quantified by analysing one single variable. The objective of the present study was to develop a multidimensional score that classifies the severity of bronchiectasis according to its prognosis. This is an observational multicentre study including 819 patients diagnosed with non-cystic fibrosis bronchiectasis using high-resolution computed tomography. 397 subjects were selected at random to construct the score while the remaining 422 were used for its validation. The outcome was 5-year all-cause mortality after radiological diagnosis. A logistic regression analysis was used to select the variables included in the final score. The final seven-point score incorporated five dichotomised variables: forced expiratory volume in 1 s % predicted (F, cut-off 50%, maximum value 2 points); age (A, cut-off 70 years, maximum value 2 points); presence of chronic colonisation by Pseudomonas aeruginosa (C, dichotomic, maximum value 1 point); radiological extension (E, number of lobes affected, cut-off two lobes, maximum value 1 point); and dyspnoea (D, cut-off grade II on the Medical Research Council scale, maximum value 1 point) to construct the FACED score. The validation cohort confirmed the score’s validity. We conclude that this easy-to-use multidimensional grading system proved capable of accurately classifying the severity of bronchiectasis according to its prognosis.
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A high FACED score of 5 to 7 is associated with median survival of approximately 5.5 years in non-cystic fibrosis bronchiectasis.
“A high FACED score (5–7) has been associated with median survival of approximately 5.5 years.”
From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [272]
The Discussion identifies FACED scores of 5–7 as severe, and the Multivariate analysis reports substantially higher five-year mortality in the severe group. The paper does not report a median survival of approximately 5.5 years; its stated follow-up was five years. (LLM, conf=0.90)
Experimental — accuracy not yet measuredThe paper says non-CF bronchiectasis transplant timing is difficult and that FACED and BSI are used to characterize severity and prognosis.
“Determining transplant timing is difficult due to the wide range of etiologies and demographics. Two non-CF bronchiectasis severity assessment tools were developed from the overall population (not limited to those with advanced lung disease): the FACED score [FEV1, Age, Chronic Pseudomonas aeruginosa, Extension to 1–2 lobes, Dyspnea by modified Medical Research Council scale] and the bronchiectasis severity index (BSI), which adds BMI and exacerbation frequency.”
From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [272]
The FACED score and bronchiectasis severity index were developed from the overall non-cystic fibrosis bronchiectasis population, not limited to advanced lung disease.
“Two non-CF bronchiectasis severity assessment tools were developed from the overall population (not limited to those with advanced lung disease): the FACED score [FEV1, Age, Chronic Pseudomonas aeruginosa, Extension to 1–2 lobes, Dyspnea by modified Medical Research Council scale] and the bronchiectasis severity index (BSI), which adds BMI and exacerbation frequency.(272, 273)”
From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [272]
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Citations
Cites
A Prediction Rule to Identify Low-Risk Patients with Community-Acquired Pneumonia
Fine, M. J., Auble, T. E., Yealy, D. M., Hanusa, B. H., Weissfeld, L. A., Singer, D. E., Coley, C. M., Marrie, T. J., & Kapoor, W. N. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701233360402 · Cited by 4,592
Celli, B. R., Cote, C. G., Marin, J. M., Casanova, C., Montes de Oca, M., Mendez, R. A., Pinto Plata, V., & Cabral, H. J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa021322 · Cited by 4,015
British Thoracic Society guideline for non-CFbronchiectasis
Pasteur, M. C., Bilton, D., Hill, A. T., & on behalf of the British Thoracic Society Bronchiectasis (non-CF) Guideline Group (2010) · Thorax · doi:10.1136/thx.2010.136119 · Cited by 1,043
(1981) · The Lancet · doi:10.1016/s0140-6736(81)91970-x · Cited by 880
Stuart, H., Bishop, J. F., Clark, T. J. H., Ac, D., Je, C., & Flenley, D. C. (1981) · PubMed · Cited by 845
Barker, A. F. (2002) · New England Journal of Medicine · doi:10.1056/nejmra012519 · Cited by 545
Martínez‐García, M. Á., Soler‐Cataluña, J. J., Perpiñá-Tordera, M., Román-Sánchez, P., & Soriano, J. B. (2007) · CHEST Journal · doi:10.1378/chest.07-0490 · Cited by 484
Self-citationBronchiectasis, Exacerbation Indices, and Inflammation in Chronic Obstructive Pulmonary Disease
Patel, I. S., Vlahos, I., Wilkinson, T. M. A., Lloyd-Owen, S. J., Donaldson, G. C., Wilks, M., Reznek, R. H., & Wedzicha, J. A. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200305-648oc · Cited by 459
Computed Tomography of Bronchiectasis
Naidich, D. P., McCauley, D. I., Khouri, N. F., Stitik, F. P., & Siegelman, S. S. (1982) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-198206000-00001 · Cited by 446
Mortality in bronchiectasis: a long-term study assessing the factors influencing survival
Loebinger, M. R., Wells, A. U., Hansell, D. M., Chinyanganya, N., Devaraj, A., Meister, M. G., & Wilson, R. (2009) · European Respiratory Journal · doi:10.1183/09031936.00003709 · Cited by 414
Validation of the St. George's Respiratory Questionnaire in Bronchiectasis
Wilson, C., JONES, P. W., O’Leary, C., COLE, P. J., & Wilson, R. C. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.2.9607083 · Cited by 387
Roberts, H. (2000) · Thorax · doi:10.1136/thorax.55.3.198 · Cited by 291
Lynch, D. A., Newell, J. D., Tschomper, B. A., et al. (1993) · Radiology · doi:10.1148/radiology.188.3.8351357 · Cited by 270
Factors Associated With Bronchiectasis in Patients With COPD
Martínez‐García, M. Á., Soler‐Cataluña, J. J., Donat-Sanz, Y., Catalán, P., Lerma, M. A., Vicente, J. B., & Perpiñá-Tordera, M. (2011) · CHEST Journal · doi:10.1378/chest.10-1758 · Cited by 268
Self-citationLung function in bronchiectasis: the influence of Pseudomonas aeruginosa
Evans, S. Y., Turner, S., Bosch, B., Cc, H., & Woodhead, M. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09081601 · Cited by 247
Trends and Burden of Bronchiectasis-Associated Hospitalizations in the United States, 1993-2006
Seitz, A. E., Olivier, K. N., Steiner, C., de Oca, R. M., Holland, S. M., & Prevots, D. R. (2010) · CHEST Journal · doi:10.1378/chest.10-0099 · Cited by 238
Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms
Fuschillo, S., Felice, A. D., & Balzano, G. (2008) · European Respiratory Journal · doi:10.1183/09031936.00069007 · Cited by 221
Diagnóstico y tratamiento de las bronquiectasias
Vendrell, M., de Gracia, J., Olveira, C., Martínez, M. Á., Girón, R. M., Máiz, L., Cantón, R., Coll, R., Escribano, A., & Solé, A. (2008) · Archivos de Bronconeumología · doi:10.1157/13128330 · Cited by 214
Self-citationO’Donnell, A. E. (2008) · CHEST Journal · doi:10.1378/chest.08-0776 · Cited by 213
Quality-of-Life Determinants in Patients With Clinically Stable Bronchiectasis
Martínez‐García, M. Á., Perpiñá-Tordera, M., Román-Sánchez, P., & Soler‐Cataluña, J. J. (2005) · CHEST Journal · doi:10.1378/chest.128.2.739 · Cited by 208
Self-citationThe effect ofPseudomonas aeruginosaon pulmonary function in patients with bronchiectasis
Davies, G., Wells, A. U., Doffman, S. R., et al. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00074605 · Cited by 190
Validation of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis
Murray, M. P., Turnbull, K., MacQuarrie, S., Pentland, J. L., & Hill, A. T. (2009) · European Respiratory Journal · doi:10.1183/09031936.00160508 · Cited by 169
Bronchiectasis: an orphan disease with a poorly-understood prognosis
Keistinen, T., Säynäjäkangas, O., Tuuponen, T., et al. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10122784 · Cited by 167
Pseudomonas aeruginosa in patients hospitalised for COPD exacerbation: a prospective study
García‐Vidal, C., Almagro, P., Romaní, V., Rodríguez‐Carballeira, M., Cuchí, E., Canales, L., Blasco, D. P., Heredia, J. L., & Garau, J. (2009) · European Respiratory Journal · doi:10.1183/09031936.00003309 · Cited by 156
Wegner, R., Jörres, R., Kirsten, D., & MAGNUSSEN, H. (1994) · European Respiratory Journal · doi:10.1183/09031936.94.07040725 · Cited by 147
A comparison of serial computed tomography and functional change in bronchiectasis
Sheehan, R. E., Wells, A. U., Copley, S. J., et al. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00284602 · Cited by 140
Analysis of the factors related to mortality in patients with bronchiectasis
Önen, Z. P., Gülbay, B. E., Şen, E., Yıldız, Ö. A., Saryal, S., Acıcan, T., & Karabıyıkoğlu, G. (2007) · Respiratory Medicine · doi:10.1016/j.rmed.2007.02.002 · Cited by 121
Decreased survival in patients with co-existent rheumatoid arthritis and bronchiectasis
Swinson, D. R., Symmons, D. P. M., Suresh, U. R., et al. (1997) · Lara D. Veeken · doi:10.1093/rheumatology/36.6.689 · Cited by 114
Lynch, D. A., Newell, J. D., Hale, V., et al. (1999) · American Journal of Roentgenology · doi:10.2214/ajr.173.1.10397099 · Cited by 102
Smith, I. E., Jurriaans, E., Diederich, S., et al. (1996) · Thorax · doi:10.1136/thx.51.9.914 · Cited by 89
Dissociation of lung function, dyspnea ratings and pulmonary extension in bronchiectasis
Martínez‐García, M. Á., Perpiñá-Tordera, M., Soler‐Cataluña, J. J., et al. (2007) · Respiratory Medicine · doi:10.1016/j.rmed.2007.06.028 · Cited by 59
Self-citationA simple score for assessing stable chronic obstructive pulmonary disease
Esteban, C., Quintana, J. M., Aburto, M., Moraza, J., & Capelastegui, A. (2006) · QJM · doi:10.1093/qjmed/hcl110 · Cited by 59
Warwick, W. J., Huang, N. Ν., Waring, W. W., Cherian, A., Brown, I. K., Stejskal-Lorenz, E., Yeung, W. H., Duhon, G., Hill, J., & Strominger, D. B. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.5.850 · Cited by 35
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Heus, P., Reitsma, J. B., Collins, G. S., Damen, J. A. A. G., Scholten, R. J. P. M., Altman, D. G., Moons, K. G. M., & Hooft, L. (2020) · Annals of Internal Medicine · doi:10.7326/m20-0193 · Cited by 70
Metadata
- Authors
- Martínez-García, M. Á., de Gracia, J., Vendrell Relat, M., Girón, R.-M., Máiz Carro, L., de la Rosa Carrillo, D., & Olveira, C.
- Affiliations
- Hospital Regional Universitario de Málaga (ES)
- ORCID
- Olveira, Casilda
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2013-11-14
- Volume
- 43
- Issue
- 5
- Pages
- 1357-1367
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2154718962
- Semantic Scholar
- 4c1a96e352f9385a5e261ebe7b133d8a91fa3b6b
- Cited by
- 503
- References
- 33
- Citations by year
- 2026: 39 · 2025: 27 · 2024: 50 · 2023: 30 · 2022: 47 · 2021: 46 · 2020: 45 · 2019: 36 · 2018: 55 · 2017: 61 · 2016: 31 · 2015: 23 · 2014: 10
- FWCI
- 17.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Epidemiology › Mycobacterium research and diagnosis
- Keywords
- non-cystic fibrosis bronchiectasis, FACED score, bronchiectasis severity, prognosis, forced expiratory volume, dyspnea, all-cause mortality, high-resolution computed tomography
- MeSH terms
- Aged, Bronchiectasis, Female, Follow-Up Studies, Forced Expiratory Volume, Humans, Male, Middle Aged, Predictive Value of Tests, Prognosis, Regression Analysis, Severity of Illness Index, Tomography, X-Ray Computed, Pulmonary Medicine, Cohort Studies, Treatment Outcome, Area Under Curve, Kaplan-Meier Estimate
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