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Cited by 478

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome

Open access
Cottin, V., Le Pavec, J., Prévot, G., Mal, H., Humbert, M., Simonneau, G., Cordier, J-F., GERM“O”P·2010·European Respiratory Journal

Abstract

This study aims to describe the haemodynamic and survival characteristics of patients with pulmonary hypertension in the recently individualised syndrome of combined pulmonary fibrosis and emphysema. A retrospective multicentre study was conducted in 40 patients (38 males; age 68±9 yrs; 39 smokers) with combined pulmonary fibrosis and emphysema, and pulmonary hypertension at right heart catheterisation. Dyspnoea was functional class II in 15%, III in 55% and IV in 30%. 6-min walk distance was 244±126 m. Forced vital capacity was 86±18%, forced expiratory volume in 1 s 78±19%, and carbon monoxide diffusion transfer coefficient 28±16% of predicted. Room air arterial oxygen tension was 7.5±1.6 kPa (56±12 mmHg). Mean pulmonary artery pressure was 40±9 mmHg, cardiac index 2.5±0.7 L·min −1 ·m −2 and pulmonary vascular resistance 521±205 dyn·s·cm −5 . 1-yr survival was 60%. Higher pulmonary vascular resistance, higher heart rate, lower cardiac index and lower carbon monoxide diffusion transfer were associated with shorter survival. Patients with combined pulmonary fibrosis and emphysema syndrome and pulmonary hypertension confirmed by right heart catheterisation have a dismal prognosis despite moderately altered lung volumes and flows and moderately severe haemodynamic parameters.

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Crossref · 10.1183/09031936.00038709

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Metadata

Authors
Cottin, V., Le Pavec, J., Prévot, G., Mal, H., Humbert, M., Simonneau, G., Cordier, J.-F., & GERM“O”P
Venue
European Respiratory Journal
Published
2009-07-30
Volume
35
Issue
1
Pages
105-111
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2132798299
Cited by
478
References
37
FWCI
20.58
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome. https://app.cochat.ai/papers/10.1183/09031936.00038709
The paper
Cottin, V., Le Pavec, J., Prévot, G., Mal, H., Humbert, M., Simonneau, G., Cordier, J.-F., & GERM“O”P. (2010). Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome. European Respiratory Journal. https://doi.org/10.1183/09031936.00038709

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.