The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
Smoking and asthma: dangerous liaisons
Open accessAbstract
Cigarette smoking and asthma interact to induce important adverse effects on clinical, prognostic and therapeutic outcomes. This review examines recent evidence on the harmful effects of smoking in asthma, possible underlying inflammatory mechanisms for this altered response, management options for these patients and potential future therapeutic directions. Active smokers, particularly females, are at risk of developing asthma. Prevalence rates for smoking in asthma are relatively close to those found in the general population. Smokers with asthma experience worse asthma control than nonsmokers with asthma. Mechanisms for the adverse effects of smoking in asthma include altered airway inflammation and corticosteroid insensitivity. Quitting smoking can improve symptoms and lung function, but the low rates of smoking cessation highlights the need for improved strategies for managing these patients. Clinical trials assessing new therapies for asthma need to enrol smokers to identify treatments that are effective in the asthma smoking phenotype.
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Cites
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Cited by
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
Barnes, P. J. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.12.1564 · Cited by 694
Impact of Air Pollution on Asthma Outcomes
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Immunologic mechanisms in asthma
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Allergy and asthma: effects of the exposure to particulate matter and biological allergens
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Metadata
- Authors
- Polosa, R., & Thomson, N. C.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2012-08-16
- Volume
- 41
- Issue
- 3
- Pages
- 716-726
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W1981266696
- Cited by
- 370
- References
- 100
- FWCI
- 11.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
