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Cited by 441

The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.

Risk factors for chronic thromboembolic pulmonary hypertension

Open access
Bonderman, D., Wilkens, H., Wakounig, S., Schäfers, H-J., Jansa, P., Lindner, J., Simkova, I., Martischnig, A. M., Dudczak, J., Sadushi, R., Skoro-Sajer, N., Klepetko, W., Lang, I. M.·2009·European Respiratory Journal

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by nonresolving pulmonary thromboemboli that can be treated by surgical pulmonary endarterectomy (PEA). The authors of the present study sought to confirm known and to identify novel CTEPH risk factors in a controlled retrospective cohort study of prevalent CTEPH cases collected in three European centres offering PEA. Data from CTEPH patients were compared with nonthromboembolic pre-capillary pulmonary arterial hypertension cohorts at the participating institutions. The study population comprised 687 patients assessed at the time of diagnosis between 1996 and 2007. Ventriculo-atrial shunts and infected pacemakers (odds ratio (OR) 76.40, 95% confidence interval (CI) 7.67–10,351), splenectomy (OR 17.87, 95% CI 1.56–2,438), previous venous thromboembolism (VTE; OR 4.52, 95% CI 2.35–9.12), recurrent VTE (OR 14.49, 95% CI 5.40–43.08), blood groups other than 0 (2.09, 95% CI 1.12–3.94), and lupus anticoagulant/antiphospholipid antibodies (OR 4.20, 95% CI 1.56–12.21) were more often associated with CTEPH. Thyroid replacement therapy (OR 6.10, 95% CI 2.73–15.05) and a history of malignancy (OR 3.76, 95% CI 1.47–10.43) emerged as novel CTEPH risk factors. In conclusion, the European database study confirmed previous knowledge of chronic thromboembolic pulmonary hypertension risk factors, and identified thyroid replacement therapy and a history of malignancy as new medical conditions associated with chronic thromboembolic pulmonary hypertension.

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Metadata

Authors
Bonderman, D., Wilkens, H., Wakounig, S., Schäfers, H.-J., Jansa, P., Lindner, J., Simkova, I., Martischnig, A. M., Dudczak, J., Sadushi, R., Skoro-Sajer, N., Klepetko, W., & Lang, I. M.
Venue
European Respiratory Journal
Published
2008-09-17
Volume
33
Issue
2
Pages
325-331
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2126713301
Cited by
441
References
71
FWCI
18.09
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Risk factors for chronic thromboembolic pulmonary hypertension. https://app.cochat.ai/papers/10.1183/09031936.00087608
The paper
Bonderman, D., Wilkens, H., Wakounig, S., Schäfers, H.-J., Jansa, P., Lindner, J., Simkova, I., Martischnig, A. M., Dudczak, J., Sadushi, R., Skoro-Sajer, N., Klepetko, W., & Lang, I. M. (2009). Risk factors for chronic thromboembolic pulmonary hypertension. European Respiratory Journal. https://doi.org/10.1183/09031936.00087608

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.