CoChat
Sign Up
Cited by 660Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseasesSmoking Behavior and Cessation

The DOI matches its Crossref record; 138 of the 139 references it cites were found in a registry or an index.

Complex chronic comorbidities of COPD

Open access
Fabbri, L. M., Luppi, F., Beghé, B., Rabe, K. F.·2008·European Respiratory Journal
DOI 10.1183/09031936.00114307
Open this paper in CoChat — free account

Abstract

Chronic obstructive pulmonary disease (COPD) is defined by fixed airflow limitation associated with an abnormal pulmonary and systemic inflammatory response of the lungs to cigarette smoke. The systemic inflammation induced by smoking may also cause chronic heart failure, metabolic syndrome and other chronic diseases, which may contribute to the clinical manifestations and natural history of COPD. Thus COPD can no longer be considered a disease only of the lungs, as it is often associated with a wide variety of systemic consequences. A better understanding of the origin and consequences of systemic inflammation, and of potential therapies, will most likely lead to better care of patients with COPD. Medical textbooks and clinical guidelines still largely ignore the fact that COPD seldom occurs in isolation. As the diagnosis and assessment of severity of COPD may be greatly affected by the presence of comorbid conditions, the current authors believe that lung function measurement, noninvasive assessment of cardiovascular and metabolic functions, and circulating inflammatory markers (e.g. C-reactive protein) might help to better characterise these patients. Similarly, preventive and therapeutic interventions should address the patient in their complexity.

Overview

Integrity signals

Registry

Crossref · 10.1183/09031936.00114307

Cites

138 of 138 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

The text we found for this paper looks like another document, so its claims and self-check weren’t run. The registry and citation checks still apply.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The text we found for this paper looks like another document, so the self-check wasn’t run.

Citations

Cites

Show all 139 references

Research works printed but not linked: 8

  1. Fabbri LM, Rabe KF. Complexity of patients with multiple chronic diseases. Proceedings of an ERS Research Seminar (Rome, February 11–12, 2007). www.ersnet.org/ers/lr/browse/default.aspx?id_dossier = 67422 Date last accessed: October 31, 2007.
  2. 2005, Exp Lung Res, 31, 72
  3. 2007, Curr Opin Pulm Med, 13, 114
  4. 1996, Diabetes Metab, 22, 37
  5. 2000, Am J Respir Crit Care Med, 161, A583
  6. 2006, Cardiovasc Res, 3, e333
  7. 2005, Cochrane Database Syst Rev, 3, CD005374
  8. 2007, Curr Opin Pulm Med, 13, 90

Cited by

Sorted by citations

Items 501–600 of 655

Related

See all

Metadata

Authors
Fabbri, L. M., Luppi, F., Beghé, B., & Rabe, K. F.
Affiliations
University of Modena and Reggio Emilia (IT)
ORCID
Venue
European Respiratory Journal
Publisher
European Respiratory Society (ERS)
Published
2007-12-31
Volume
31
Issue
1
Pages
204-212
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
DOI
10.1183/09031936.00114307
OpenAlex
W2165340553
Cited by
660
References
139
Citations by year
2026: 8 · 2025: 16 · 2024: 20 · 2023: 17 · 2022: 26 · 2021: 19 · 2020: 35 · 2019: 25 · 2018: 36 · 2017: 48 · 2016: 31 · 2015: 50 · 2014: 68 · 2013: 55 · 2012: 59
FWCI
28.24
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • European Respiratory Journal (publishedVersion)
  • PubMed (publishedVersion)
  • BOA (University of Milano-Bicocca) (submittedVersion)
  • IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
  • INFM-OAR (INFN Catania) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords
chronic obstructive pulmonary disease, comorbidities, systemic inflammation, chronic heart failure, metabolic syndrome, cigarette smoking, C-reactive protein, inflammatory markers, COPD severity assessment, cardiovascular function, COPD management
MeSH terms
Chronic Disease, Health Status, Humans, Inflammation, Lung, Models, Biological, Prognosis, Risk Factors, Smoking, Pulmonary Medicine, Comorbidity, Guidelines as Topic, Pulmonary Disease, Chronic Obstructive, Overweight

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review