The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Volumetric computed tomography screening for lung cancer: three rounds of the NELSON trial
Open accessAbstract
Several medical associations recommended lung cancer screening by low-dose computed tomography scanning for high-risk groups. Counselling of the candidates on the potential harms and benefits and their lung cancer risk is a prerequisite for screening. In the NELSON trial, screenings are considered positive for (part) solid lung nodules with a volume >500 mm 3 and for (part) solid or nonsolid nodules with a volume-doubling time <400 days. For this study, the performance of the NELSON strategy in three screening rounds was evaluated and risk calculations were made for a follow-up period of 5.5 years. 458 (6%) of the 7582 participants screened had a positive screen result and 200 (2.6%) were diagnosed with lung cancer. The positive screenings had a predictive value of 40.6% and only 1.2% of all scan results were false-positive. In a period of 5.5 years, the risk of screen-detected lung cancer strongly depends on the result of the first scan: 1.0% after a negative baseline result, 5.7% after an indeterminate baseline and 48.3% after a positive baseline. The screening strategy yielded few positive and false-positive scans with a reasonable positive predictive value. The 5.5-year lung cancer risk calculations aid clinicians in counselling candidates for lung cancer screening with low-dose computed tomography.
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Citations
Cites
Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
The National Lung Screening Trial Research Team (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1102873 · Cited by 11,064
Goldstraw, P., Crowley, J., Chansky, K., Giroux, D. J., Groome, P. A., Rami-Porta, R., Postmus, P. E., Rusch, V., & Sobin, L. (2007) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e31812f3c1a · Cited by 3,655
Cited by
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial
de Koning, H. J., van der Aalst, C. M., de Jong, P. A., Scholten, E. T., Nackaerts, K., Heuvelmans, M. A., Lammers, J.-W. J., Weenink, C., Yousaf-Khan, U., Horeweg, N., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1911793 · Cited by 3,624
Self-citationMacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N. C., Mayo, J. R., Mehta, A. C., Ohno, Y., Powell, C. A., Prokop, M., et al. (2017) · Radiology · doi:10.1148/radiol.2017161659 · Cited by 2,491
European position statement on lung cancer screening
Oudkerk, M., Devaraj, A., Vliegenthart, R., Henzler, T., Prosch, H., Heussel, C. P., Bastarrika, G., Sverzellati, N., Mascalchi, M., Delorme, S., et al. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30861-6 · Cited by 587
Self-citationPerformance of Lung-RADS in the National Lung Screening Trial: A Retrospective Assessment
Pinsky, P. F., Gierada, D. S., Black, W., Munden, R., Nath, H., Aberle, D., & Kazerooni, E. (2015) · Annals of Internal Medicine · doi:10.7326/m14-2086 · Cited by 508
Mazzone, P. J., Silvestri, G. A., Patel, S., Kanne, J. P., Kinsinger, L. S., Wiener, R. S., Soo Hoo, G., & Detterbeck, F. C. (2018) · Chest · doi:10.1016/j.chest.2018.01.016 · Cited by 348
Metadata
- Authors
- Horeweg, N., van der Aalst, C. M., Vliegenthart, R., Zhao, Y., Xie, X., Scholten, E. T., Mali, W., Thunnissen, E., Weenink, C., Groen, H. J. M., Lammers, J.-W. J., Nackaerts, K., van Rosmalen, J., Oudkerk, M., & de Koning, H. J.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2013-07-11
- Volume
- 42
- Issue
- 6
- Pages
- 1659-1667
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2108856453
- Cited by
- 237
- References
- 2
- FWCI
- 17.54
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Horeweg, N., van der Aalst, C. M., Vliegenthart, R., Zhao, Y., Xie, X., Scholten, E. T., Mali, W., Thunnissen, E., Weenink, C., Groen, H. J. M., Lammers, J.-W. J., Nackaerts, K., van Rosmalen, J., Oudkerk, M., & de Koning, H. J. (2013). Volumetric computed tomography screening for lung cancer: three rounds of the NELSON trial. European Respiratory Journal. https://doi.org/10.1183/09031936.00197712
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
