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The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP

Open access
Nagai, S, Kitaichi, M, Itoh, H, Nishimura, K, Izumi, T, Colby, TV·1998·European Respiratory Journal

Abstract

Based on past difficulties in clinically differentiating patients with idiopathic pulmonary fibrosis (IPF), bronchiolitis obliterans-organizing pneumonia (BOOP), and nonspecific interstitial pneumonia/fibrosis (NSIP), which all manifest clinically as interstitial lung disease, experience with pathologically confirmed examples of the three diseases was reviewed to compare clinical profiles and prognosis and to define NSIP more clearly. Thirty-one patients (15 males and 16 females) were pathologically identified as NSIP and subclassified into either the cellular (n=16) or fibrotic group (n=15). All 31 patients were clinically considered to be idiopathic NSIP cases. Patients with idiopathic BOOP (n=16) and IPF (n=64) were compared with the NSIP patients. Subacute presentation of interstitial lung disease characterized both idiopathic NSIP and idiopathic BOOP. NSIP patients showed volume loss on a chest radiograph (29.0%) and honeycombing on a computed tomography scan (25.8%); these features were not found in BOOP patients. Bronchoalveolar lavage lymphocytosis was characteristic of both BOOP and NSIP. Two subgroups of NSIP can be recognized histologically: patients in the fibrotic group had a less favourable outcome than those in the cellular group. BOOP and NSIP had a more favourable outcome than IPF. In conclusion, idiopathic nonspecific interstitial pneumonia can be differentiated from other types of idiopathic interstitial pneumonia, both pathologically and clinically.

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Metadata

Authors
Nagai, S., Kitaichi, M., Itoh, H., Nishimura, K., Izumi, T., & Colby, T.
Venue
European Respiratory Journal
Published
1998-11-01
Volume
12
Issue
5
Pages
1010-1019
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2138421611
Cited by
339
References
19
FWCI
15.87
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. https://app.cochat.ai/papers/10.1183/09031936.98.12051010
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Nagai, S., Kitaichi, M., Itoh, H., Nishimura, K., Izumi, T., & Colby, T. (1998). Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. European Respiratory Journal. https://doi.org/10.1183/09031936.98.12051010

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.