The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature
Abstract
The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE) is relevant for management decisions but is currently unknown. We performed a meta-analysis of studies including consecutive PE patients followed for CTEPH. Study cohorts were predefined as “all comers”, “survivors” or “survivors without major comorbidities”. CTEPH incidences were calculated using random effects models. We selected 16 studies totalling 4047 PE patients who were mostly followed up for >2-years. In 1186 all comers (two studies), the pooled CTEPH incidence was 0.56% (95% CI 0.1–1.0). In 999 survivors (four studies) CTEPH incidence was 3.2% (95% CI 2.0–4.4). In 1775 survivors without major comorbidities (nine studies), CTEPH incidence was 2.8% (95% CI 1.5–4.1). Both recurrent venous thromboembolism and unprovoked PE were significantly associated with a higher risk of CTEPH, with odds ratios of 3.2 (95% CI 1.7–5.9) and 4.1 (95% CI 2.1–8.2) respectively. The pooled CTEPH incidence in 12 studies that did not use right heart catheterisation as the diagnostic standard was 6.3% (95% CI 4.1–8.4). The 0.56% incidence in the all-comer group probably provides the best reflection of the incidence of CTEPH after PE on the population level. The ∼3% incidences in the survivor categories may be more relevant for daily clinical practice. Studies that assessed CTEPH diagnosis by tests other than right heart catheterisation provide overestimated CTEPH incidences.
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Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
(2008) · Cited by 3,790
Galiè, N., Humbert, M., Vachiery, J.-L., Gibbs, S., Lang, I., Torbicki, A., Simonneau, G., Peacock, A., Vonk Noordegraaf, A., Beghetti, M., et al. (2015) · European Respiratory Journal · doi:10.1183/13993003.01032-2015 · Cited by 3,172
Self-citationIncidence of Chronic Thromboembolic Pulmonary Hypertension after Pulmonary Embolism
Pengo, V., Lensing, A. W. A., Prins, M. H., Marchiori, A., Davidson, B. L., Tiozzo, F., Albanese, P., Biasiolo, A., Pegoraro, C., Iliceto, S., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032274 · Cited by 1,828
2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism
Konstantinides, S., Torbicki, A., Agnelli, G., Danchin, N., Fitzmaurice, D., Galiè, N., Gibbs, J. S. R., Huisman, M., Humbert, M., Kucher, N., et al. (2014) · Kardiologia Polska · doi:10.5603/kp.2014.0211 · Cited by 1,349
Self-citationChronic Thromboembolic Pulmonary Hypertension
Hoeper, M. M., Mayer, E., Simonneau, G., & Rubin, L. J. (2006) · Circulation · doi:10.1161/circulationaha.105.602565 · Cited by 1,148
Pepke-Zaba, J., Delcroix, M., Lang, I., Mayer, E., Jansa, P., Ambroz, D., Treacy, C., D'Armini, A. M., Morsolini, M., Snijder, R., et al. (2011) · Circulation · doi:10.1161/circulationaha.110.015008 · Cited by 1,059
Self-citationA global view of pulmonary hypertension
Hoeper, M. M., Humbert, M., Souza, R., Idrees, M., Kawut, S. M., Sliwa-Hahnle, K., Jing, Z.-C., & Gibbs, J. S. R. (2016) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(15)00543-3 · Cited by 1,039
Longterm Follow-up of Patients with Pulmonary Thromboembolism
Riedel, M., Stanek, V., Widimsky, J., & Prerovsky, I. (1982) · Chest · doi:10.1378/chest.81.2.151 · Cited by 830
Cited by
Konstantinides, S. V., Meyer, G., Becattini, C., Bueno, H., Geersing, G.-J., Harjola, V.-P., Huisman, M. V., Humbert, M., Jennings, C. S., Jiménez, D., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz405 · Cited by 4,916
Self-citationKonstantinides, S. V., Meyer, G., Becattini, C., Bueno, H., Geersing, G.-J., Harjola, V.-P., Huisman, M. V., Humbert, M., Jennings, C. S., Jiménez, D., et al. (2019) · European Respiratory Journal · doi:10.1183/13993003.01647-2019 · Cited by 1,619
Self-citationEpidemiology and prevention of venous thromboembolism
Lutsey, P. L., & Zakai, N. A. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00787-6 · Cited by 507
Huisman, M. V., Barco, S., Cannegieter, S. C., Le Gal, G., Konstantinides, S. V., Reitsma, P. H., Rodger, M., Noordegraaf, A. V., & Klok, F. A. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.28 · Cited by 336
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Metadata
- Authors
- Ende-Verhaar, Y. M., Cannegieter, S. C., Vonk Noordegraaf, A., Delcroix, M., Pruszczyk, P., Mairuhu, A. T. A., Huisman, M. V., & Klok, F. A.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2017-02
- Volume
- 49
- Issue
- 2
- Pages
- 1601792
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2589199695
- Cited by
- 521
- References
- 49
- FWCI
- 34.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ende-Verhaar, Y. M., Cannegieter, S. C., Vonk Noordegraaf, A., Delcroix, M., Pruszczyk, P., Mairuhu, A. T. A., Huisman, M. V., & Klok, F. A. (2017). Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature. European Respiratory Journal. https://doi.org/10.1183/13993003.01792-2016
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