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Cited by 531

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Tuberculosis and lung damage: from epidemiology to pathophysiology

Open access
Ravimohan, Shruthi, Kornfeld, Hardy, Weissman, Drew, Bisson, Gregory P.·2018·European Respiratory Review

Abstract

A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high prevalence and its association with reduced quality of life. Importantly, specific host and pathogen factors causing lung impairment remain unclear. Host immune responses probably play a dominant role in lung damage, as excessive inflammation and elevated expression of lung matrix-degrading proteases are common during TB. Variability in host genes that modulate these immune responses may determine the severity of lung impairment, but this hypothesis remains largely untested. In this review, we provide an overview of the epidemiological literature on post-TB lung impairment and link it to data on the pathogenesis of lung injury from the perspective of dysregulated immune responses and immunogenetics.

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Metadata

Authors
Ravimohan, S., Kornfeld, H., Weissman, D., & Bisson, G. P.
Venue
European Respiratory Review
Published
2018-02-28
Volume
27
Issue
147
Pages
170077
ISSN
  • 0905-9180 (ISSN-L)
  • 1600-0617
OpenAlex
W2788443790
Cited by
531
References
9
FWCI
26.97
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Tuberculosis and lung damage: from epidemiology to pathophysiology. https://app.cochat.ai/papers/10.1183/16000617.0077-2017
The paper
Ravimohan, S., Kornfeld, H., Weissman, D., & Bisson, G. P. (2018). Tuberculosis and lung damage: from epidemiology to pathophysiology. European Respiratory Review. https://doi.org/10.1183/16000617.0077-2017

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.