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Cited by 213

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

FastGroupII: A web-based bioinformatics platform for analyses of large 16S rDNA libraries

Open access
Yu, Yanan, Breitbart, Mya, McNairnie, Pat, Rohwer, Forest·2006·BMC Bioinformatics

Abstract

Background: High-throughput sequencing makes it possible to rapidly obtain thousands of 16S rDNA sequences from environmental samples. Bioinformatic tools for the analyses of large 16S rDNA sequence databases are needed to comprehensively describe and compare these datasets. Results: FastGroupII is a web-based bioinformatics platform to dereplicate large 16S rDNA libraries. FastGroupII provides users with the option of four different dereplication methods, performs rarefaction analysis, and automatically calculates the Shannon-Wiener Index and Chao1. FastGroupII was tested on a set of 16S rDNA sequences from coral-associated Bacteria. The different grouping algorithms produced similar, but not identical, results. This suggests that 16S rDNA datasets need to be analyzed in multiple ways when being used for community ecology studies. Conclusion: FastGroupII is an effective bioinformatics tool for the trimming and dereplication of 16S rDNA sequences. Several standard diversity indices are calculated, and the raw sequences are prepared for downstream analyses.

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Metadata

Authors
Yu, Y., Breitbart, M., McNairnie, P., & Rohwer, F.
Venue
BMC Bioinformatics
Published
2006-02-07
Volume
7
Issue
1
Pages
57-57
ISSN
1471-2105 (ISSN-L)
OpenAlex
W1551834832
Cited by
213
References
2
FWCI
6.02
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: FastGroupII: A web-based bioinformatics platform for analyses of large 16S rDNA libraries. https://app.cochat.ai/papers/10.1186/1471-2105-7-57
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Yu, Y., Breitbart, M., McNairnie, P., & Rohwer, F. (2006). FastGroupII: A web-based bioinformatics platform for analyses of large 16S rDNA libraries. BMC Bioinformatics. https://doi.org/10.1186/1471-2105-7-57

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