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Treatment outcome of smear-positive pulmonary tuberculosis patients in Tigray Region, Northern Ethiopia
Open accessAbstract
BACKGROUND: Monitoring the outcome of tuberculosis treatment and understanding the specific reasons for unsuccessful treatment outcome are important in evaluating the effectiveness of tuberculosis control program. This study investigated tuberculosis treatment outcomes and predictors for unsuccessful treatment outcome in the Tigray region of Ethiopia. METHODS: Medical records of smear-positive pulmonary tuberculosis (PTB) patients registered from September 2009 to June 2011 in 15 districts of Tigray region, Northern Ethiopia, were reviewed. Additional data were collected using a structured questionnaire administered through house-to-house visits by trained nurses. Tuberculosis treatment outcomes were assessed according to WHO guidelines. The association of unsuccessful treatment outcome with socio-demographic and clinical factors was analyzed using logistic regression model. RESULTS: Out of the 407 PTB patients (221 males and 186 females) aged 15 years and above, 89.2% had successful and 10.8% had unsuccessful treatment outcome. In the final multivariate logistic model, the odds of unsuccessful treatment outcome was higher among patients older than 40 years of age (adj. OR=2.50, 95% CI: 1.12-5.59), family size greater than 5 persons (adj. OR=3.26, 95% CI: 1.43-7.44), unemployed (adj. OR=3.10, 95% CI: 1.33-7.24) and among retreatment cases (adj. OR=2.00, 95% CI: 1.37-2.92) as compared to their respective comparison groups. CONCLUSIONS: Treatment outcome among smear-positive PTB patients was satisfactory in the Tigray region of Ethiopia. Nonetheless, those patients at high risk of an unfavorable treatment outcome should be identified early and given additional follow-up and social support.
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“However, only a few studies have been conducted to assess the treatment outcome of TB patients in northern Ethiopia [7,9].”
From Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia (2014) · cites this paper as [7]
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“The implementation of DOTS as a treatment strategy in Ethiopia has shown a marked success in improving patient adherence to treatment and consequently increasing the chance of patient cure [7].”
From Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia (2014) · cites this paper as [7]
In the citing paper
“Studies conducted in other parts of Ethiopia [7,14] and Tanzania [15] reported higher successful treatment outcomes by using community health extension workers to follow-up patients.”
From Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia (2014) · cites this paper as [7]
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Citations
Cites
Global tuberculosis control 2010
Behera, D. (2012) · The Indian Journal of Medical Research · Cited by 1,262
Global Epidemiology of Tuberculosis: Prospects for Control
Lönnroth, K., & Raviglione, M. C. (2008) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0028-1085700 · Cited by 299
Evolution of WHO policies for tuberculosis control, 1948–2001
Raviglione, M. C., & Pío, A. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07880-7 · Cited by 264
Shargie, E. B., & Lindtjørn, B. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040037 · Cited by 204
Datiko, D. G., & Lindtjørn, B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005443 · Cited by 173
Veen, J., Raviglione, M. C., Rieder, H. L., Migliori, G. B., Gräf, P., Grzemska, M., & Zalesky, R. (1998) · European Respiratory Journal · doi:10.1183/09031936.98.12020505 · Cited by 164
Tessema, B., Muche, A., Bekele, A., Reissig, D., Emmrich, F., & Sack, U. (2009) · BMC Public Health · doi:10.1186/1471-2458-9-371 · Cited by 154
Defaulting from DOTS and its determinants in three districts of Arsi Zone in Ethiopia.
Tekle, B., Mariam, D. H., & Ali, A. (2002) · PubMed · Cited by 153
Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study
Vasankari, T., Holmström, P., Ollgren, J. P., Liippo, K. K., Kokki, M. H., & Ruutu, P. (2007) · BMC Public Health · doi:10.1186/1471-2458-7-291 · Cited by 122
Principles of Medicine in Africa
Mabey, D. C. W. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9780511751660 · Cited by 120
de Albuquerque, M. D. F. P. M., Ximenes, R. A. D. A., Lucena‐Silva, N., de Souza, W. V., Dantas, A. T., Dantas, O. M. S., & Rodrigues, L. C. (2007) · Cadernos de Saúde Pública · doi:10.1590/s0102-311x2007000700008 · Cited by 119
Factors associated with poor tuberculosis treatment outcome in the Southern Region of Ethiopia.
Muñoz-Sellart, M., Cuevas, L. E., Tumato, M., Merid, Y., & Yassin, M. A. (2010) · PubMed · Cited by 111
Current status of treatment completion and fatality among tuberculosis patients in Spain.
Caylà, J. A., Caminero, J. A., Rey, R. D., Lara, N., Vallès, X., & Galdós-Tangüis, H. (2004) · PubMed · Cited by 85
Sputum smear conversion during directly observed treatment for tuberculosis
Rieder, H. L. (1996) · Tubercle and Lung Disease · doi:10.1016/s0962-8479(96)90026-x · Cited by 85
Alpert, P. L., Munsiff, S. S., Gourevitch, M. N., Greenberg, B. M., & Klein, R. S. (1997) · Clinical Infectious Diseases · doi:10.1093/clind/24.4.661 · Cited by 84
Risk factors for pulmonary tuberculosis in Estonia.
Tekkel, M., Rahu, M., Loit, H. ‐., & Baburin, A. (2002) · PubMed · Cited by 82
Getahun, B., Ameni, G., Biadgilign, S., & Medhin, G. (2011) · BMC Infectious Diseases · doi:10.1186/1471-2334-11-127 · Cited by 77
Principles of Medicine in Africa
(2004) · Journal of the Royal Society of Medicine · doi:10.1177/014107680409700918 · Cited by 70
Treatment outcome of new culture positive pulmonary tuberculosis in Norway
Farah, M. G., Tverdal, A., Steen, T. W., Heldal, E., Brantsæter, A. B., & Bjune, G. A. (2005) · BMC Public Health · doi:10.1186/1471-2458-5-14 · Cited by 69
Yassin, M. A., Takele, L., Gebresenbet, S., Girma, E., Lera, M., Lendebo, E., & Cuevas, L. E. (2004) · Scandinavian Journal of Infectious Diseases · doi:10.1080/00365540410020848 · Cited by 69
Outcome of patients treated for tuberculosis in Vaud County, Switzerland.
Zellweger, J. P., & Coulon, P. (1998) · PubMed · Cited by 66
Attitude and social consequences of tuberculosis in Addis Ababa, Ethiopia
Gelaw, M., Genebo, T., Dejene, T. A., Lemma, E., & Eyob, G. (2001) · East African Medical Journal · doi:10.4314/eamj.v78i7.9014 · Cited by 66
Focusing Tuberculosis Contact Tracing by Smear Grading of Index Cases
Liippo, K. K., Kulmala, K., & Tala, E. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/148.1.235 · Cited by 55
Vijay, S., Kumar, P., Chauhan, L. S., Rao, S. V. N., & Vaidyanathan, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021008 · Cited by 53
Treatment outcomes among pulmonary tuberculosis patients at treatment centers in Ibadan, Nigeria
Fatiregun, A. A., Ojo, A., & Bamgboye, A. E. (2009) · Annals of African Medicine · doi:10.4103/1596-3519.56237 · Cited by 52
Talay, F., Kümbetli, Ş., & Altın, S. (2008) · Japanese Journal of Infectious Diseases · doi:10.7883/yoken.jjid.2008.25 · Cited by 45
Exploring the determinants of treatment success for tuberculosis cases in Europe.
Falzon, D., Strat, Y. L., Belghiti, F. A. E., & Infuso, A. (2005) · PubMed · Cited by 45
van den Boogaard, J., Lyimo, R. A., Irongo, C. F., Boeree, M. J., Schaalma, H. P., Aarnoutse, R. E., & Kibiki, G. S. (2009) · PubMed · Cited by 42
Harries, A. D., Nyirenda, T. E., Banerjee, A., Boeree, M. J., & Salaniponi, F. M. L. (1999) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(99)90153-0 · Cited by 41
Factors associated with treatment outcomes in pulmonary tuberculosis in northeastern Thailand.
Anunnatsiri, S., Chetchotisakd, P., & WANKE, C. A. (2005) · PubMed · Cited by 39
Treatment Outcome of Pulmonary Tuberculosis in Eastern Taiwan—Experience at a Medical Center
Lee, J., Wu, R.-L., Lee, Y.-S., Wu, Y.-C., & Chiang, C. (2007) · Journal of the Formosan Medical Association · doi:10.1016/s0929-6646(09)60212-6 · Cited by 34
Nm, N. N. R., Ns, M., Wan Mohammad, Z., Sharina, D., & Husain, N. R. N. (2011) · Malaysian Journal of Public Health Medicine · Cited by 34
The quality of tuberculosis diagnosis in districts of Tigray region of Northern Ethiopia
Mesfin, M. M., Tasew, T. W., & Richard, M. J. (2006) · Ethiopian Journal of Health Development · doi:10.4314/ejhd.v19i4.9993 · Cited by 29
Mitike, G., Kebede, D., & Yeneneh, H. (1997) · PubMed · Cited by 29
Community participation in malaria epidemic control in highland areas of southern Oromia, Ethiopia
Deressa, W. A., Olana, D., & Chibsa, S. (2005) · Ethiopian Journal of Health Development · doi:10.4314/ejhd.v19i1.9964 · Cited by 28
Belo, M., Luiz, R. R., Teixeira, E. G., Hanson, C. L., & Trajman, A. (2011) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.10.0706 · Cited by 26
Progress toward tuberculosis control and determinants of treatment outcomes--Kazakhstan, 2000-2002.
Bumburidi, Y., Ajeilat, S., Dadu, A., Aitmagambetova, I., Ershova, J. V., Fagan, R., & Favorov, M. O. (2006) · PubMed · Cited by 22
Principles of medicine in Africa, 3rd edition
Warrell, D. A. (2005) · Clinical Medicine · doi:10.7861/clinmedicine.5-5-526a · Cited by 10
Mesfin, M. M. (2006) · Ethiopian Journal of Health Development · doi:10.4314/ejhd.v19i4.9991 · Cited by 2
[Cohort analysis for treatment outcomes TB pulmonary cases bacteriologically confirmed in Poland].
Szczuka, I. (2005) · PubMed · Cited by 2
Research works printed but not linked: 6
- World Health Organization: Global Tuberculosis Control. 2011, Geneva: World Health Organization
- Ministry of Health of Ethiopia: Tuberculosis, Leprosy and TB/HIV Prevention and Control Programme Manual. Addis Ababa: MOH. 2008, 4
- Federal Ministry of Health: Overview of National TB Control Implementation status. 2011, Gondar, Ethiopia: Sixth National TB Research Workshop, Gondar University, 6–8 June 2011
- Tigray Health Bureau: nnual TB performance report in Tigray region. 2011, Gondar, Ethiopia: Sixth National TB Research Workshop, Gondar University, 6–8 June 2011
- Veen J, Raviglione M, Rieder HL, Migliori GB, Graf P, Grzemska M, Zalesky R: Standardized tuberculosis treatment outcome monitoring in Europe. Recommendations of a Working Group of the World Health Organization (WHO) and the European Region of the International Union Against Tuberculosis and Lung Disease (IUATLD) for uniform reporting by cohort analysis of treatment outcome in tuberculosis patients. Eur Respir J. 1998, 12: 505-510. http://erj.ersjournals.com/content/12/2/505.long , · DOI
- World Health Organization: Global tuberculosis control 2008. Surveillance, planning, fi nancing. WHO report 2008. WHO/HTM/TB/2008.393. 2008, Geneva, Switzerland: WHO
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Gebrezgabiher, G., Romha, G., Ejeta, E., Asebe, G., Zemene, E., & Ameni, G. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150560 · Cited by 129
Zeru, A. B., Tesfaw, G., Dejene, T., & Woldemichael, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144244 · Cited by 82
Eshetie, S., Gizachew, M., Alebel, A., & van Soolingen, D. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194675 · Cited by 73
Asres, A., Jerene, D., & Deressa, W. A. (2018) · BMC Pulmonary Medicine · doi:10.1186/s12890-018-0628-2 · Cited by 71
Metadata
- Authors
- Berhe, G., Enquselassie, F., & Aseffa, A.
- Affiliations
- Mekelle University (ET)
- Addis Ababa University (ET)
- Armauer Hansen Research Institute (ET)
- Corresponding author
- Berhe, Gebretsadik
- Venue
- BMC Public Health
- Published
- 2012-07-23
- Volume
- 12
- Issue
- 1
- Pages
- 537-537
- ISSN
- 1471-2458 (ISSN-L)
- PMC
- PMC3414747
- OpenAlex
- W2027862365
- Cited by
- 146
- References
- 42
- Citations by year
- 2025: 4 · 2024: 8 · 2023: 3 · 2022: 6 · 2021: 21 · 2020: 14 · 2019: 14 · 2018: 18 · 2017: 14 · 2016: 14 · 2015: 9 · 2014: 14 · 2013: 6 · 2012: 1
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Greater South Information System
- Funders
- Armauer Hansen Research Institute
- Addis Ababa University
- Mekelle University
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › HIV, TB, and STIs Epidemiology
- Keywords
- smear-positive tuberculosis, tuberculosis treatment outcomes, treatment failure, predictors of treatment failure, retreatment tuberculosis, household size, unemployment, old age, Tigray
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Ethiopia, Female, Humans, Male, Middle Aged, Retrospective Studies, Sputum, Tuberculosis, Pulmonary, Treatment Outcome, Young Adult
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