Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand
Open accessAbstract
Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand.
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Rijken et al. (2011) reported that a pregnant woman on the western border of Thailand developed chloroquine-resistant vivax malaria despite adequate chloroquine treatment.
“Similarly, Rijken et al. (2011) reported that a pregnant woman on the western border of Thailand developed chloroquine-resistant vivax malaria despite adequate chloroquine treatment [139].”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as [139]
Rijken et al. (2011) reported that a pregnant woman on the western border of Thailand developed chloroquine-resistant vivax malaria despite adequate chloroquine treatment.
“Similarly, Rijken et al. (2011) reported that a pregnant woman on the western border of Thailand developed chloroquine-resistant vivax malaria despite adequate chloroquine treatment [139].”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as Rijken et al. (2011)
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Self-citation
- Authors
- Rijken, M. J., Boel, M. E., Russell, B., Imwong, M., Leimanis, M. L., Phyo, A. P., Muehlenbachs, A., Lindegardh, N., McGready, R., Rénia, L., Snounou, G., Singhasivanon, P., & Nosten, F.
- Affiliations
- Shoklo Malaria Research Unit (TH)
- Agency for Science, Technology and Research (SG)
- Mahidol University (TH)
- University of Washington (US)
- Corresponding author
- Rijken, Marcus J
- Boel, Machteld E
- ORCID
- Venue
- Malaria Journal
- Published
- 2011-05-05
- Volume
- 10
- Issue
- 1
- Pages
- 113-113
- ISSN
- 1475-2875 (ISSN-L)
- PMC
- PMC3112451
- OpenAlex
- W2140302730
- Cited by
- 62
- References
- 19
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 3 · 2023: 3 · 2021: 5 · 2020: 4 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 6 · 2015: 7 · 2014: 4 · 2013: 4 · 2012: 11
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Malaria Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion, cc-by)
- HAL (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Greater South Information System
- Funders
- Wellcome Trust
- Institut National de la Santé et de la Recherche Médicale
- Mahidol University
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical compounds biological activities
- Life Sciences › Immunology and Microbiology › Parasitology › Toxoplasma gondii Research Studies
- Keywords
- chloroquine resistance, Plasmodium vivax, vivax malaria, malaria in pregnancy, recrudescence, in vitro susceptibility, molecular genotyping, growth restriction, Thailand
- MeSH terms
- Adult, Antimalarials, Chloroquine, Drug Resistance, Female, Genotype, Humans, Plasmodium vivax, Pregnancy, Pregnancy Complications, Infectious, Thailand, DNA, Protozoan, Malaria, Vivax, Parasitic Sensitivity Tests
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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