The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The complexities of malaria disease manifestations with a focus on asymptomatic malaria
Open accessAbstract
Malaria is a serious parasitic disease in the developing world, causing high morbidity and mortality. The pathogenesis of malaria is complex, and the clinical presentation of disease ranges from severe and complicated, to mild and uncomplicated, to asymptomatic malaria. Despite a wealth of studies on the clinical severity of disease, asymptomatic malaria infections are still poorly understood. Asymptomatic malaria remains a challenge for malaria control programs as it significantly influences transmission dynamics. A thorough understanding of the interaction between hosts and parasites in the development of different clinical outcomes is required. In this review, the problems and obstacles to the study and control of asymptomatic malaria are discussed. The human and parasite factors associated with differential clinical outcomes are described and the management and treatment strategies for the control of the disease are outlined. Further, the crucial gaps in the knowledge of asymptomatic malaria that should be the focus of future research towards development of more effective malaria control strategies are highlighted.
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Haemoglobin C protects against clinical Plasmodium falciparum malaria
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Cited by
The silent threat: asymptomatic parasitemia and malaria transmission
Lindblade, K. A., Steinhardt, L., Samuels, A., Kachur, S. P., & Slutsker, L. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.13.45 · Cited by 600
Targeting Asymptomatic Malaria Infections: Active Surveillance in Control and Elimination
Sturrock, H. J. W., Hsiang, M. S., Cohen, J. M., Smith, D. L., Greenhouse, B., Bousema, T., & Gosling, R. D. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001467 · Cited by 341
The role of submicroscopic parasitemia in malaria transmission: What is the evidence?
Lin, J. T., Saunders, D. L., & Meshnick, S. R. (2014) · Trends in Parasitology · doi:10.1016/j.pt.2014.02.004 · Cited by 271
Tiono, A. B., Ouédraogo, A., Ogutu, B., Diarra, A., Coulibaly, S., Gansané, A., Sirima, S. B., O’Neil, G., Mukhopadhyay, A., & Hamed, K. (2013) · Malaria Journal · doi:10.1186/1475-2875-12-79 · Cited by 118
Nega, D., Dana, D., Tefera, T., & Eshetu, T. (2015) · PLOS ONE · doi:10.1371/journal.pone.0123630 · Cited by 86
Metadata
- Authors
- Laishram, D. D., Sutton, P. L., Nanda, N., Sharma, V. L., Sobti, R. C., Carlton, J. M., & Joshi, H.
- Venue
- Malaria Journal
- Published
- 2012-01-31
- Volume
- 11
- Issue
- 1
- Pages
- 29-29
- ISSN
- 1475-2875 (ISSN-L)
- OpenAlex
- W2164734679
- Cited by
- 340
- References
- 6
- FWCI
- 18.52
- Type
- journal article
- Language
- en
- Open access
- gold
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- Laishram, D. D., Sutton, P. L., Nanda, N., Sharma, V. L., Sobti, R. C., Carlton, J. M., & Joshi, H. (2012). The complexities of malaria disease manifestations with a focus on asymptomatic malaria. Malaria Journal. https://doi.org/10.1186/1475-2875-11-29
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
