The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
ScanImage: Flexible software for operating laser scanning microscopes
Open accessAbstract
BACKGROUND: Laser scanning microscopy is a powerful tool for analyzing the structure and function of biological specimens. Although numerous commercial laser scanning microscopes exist, some of the more interesting and challenging applications demand custom design. A major impediment to custom design is the difficulty of building custom data acquisition hardware and writing the complex software required to run the laser scanning microscope. RESULTS: We describe a simple, software-based approach to operating a laser scanning microscope without the need for custom data acquisition hardware. Data acquisition and control of laser scanning are achieved through standard data acquisition boards. The entire burden of signal integration and image processing is placed on the CPU of the computer. We quantitate the effectiveness of our data acquisition and signal conditioning algorithm under a variety of conditions. We implement our approach in an open source software package (ScanImage) and describe its functionality. CONCLUSIONS: We present ScanImage, software to run a flexible laser scanning microscope that allows easy custom design.
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Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
Trachtenberg, J. T., Chen, B. E., Knott, G. W., Feng, G., Sanes, J. R., Welker, E., & Svoboda, K. (2002) · Nature · doi:10.1038/nature01273 · Cited by 1,927
Self-citationWhite, E. L., & Keller, A. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902620103 · Cited by 150
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Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474
Self-citationIn vivo three-photon microscopy of subcortical structures within an intact mouse brain
Horton, N. G., Wang, K., Kobat, D., Clark, C. G., Wise, F. W., Schaffer, C. B., & Xu, C. (2013) · Nature Photonics · doi:10.1038/nphoton.2012.336 · Cited by 1,505
Imaging large-scale neural activity with cellular resolution in awake, mobile mice
Dombeck, D. A., Khabbaz, A. N., Collman, F., Adelman, T. L., & Tank, D. W. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.003 · Cited by 1,099
An in vivo model of functional and vascularized human brain organoids
Mansour, A. A., Gonçalves, J. T., Bloyd, C. W., Li, H., Fernandes, S., Quang, D., Johnston, S., Parylak, S. L., Jin, X., & Gage, F. H. (2018) · Nature Biotechnology · doi:10.1038/nbt.4127 · Cited by 1,211
Transient and persistent dendritic spines in the neocortex in vivo
Holtmaat, A. J. G. D., Trachtenberg, J. T., Wilbrecht, L., Shepherd, G. M., Zhang, X., Knott, G. W., & Svoboda, K. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.003 · Cited by 1,131
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Metadata
- Authors
- Pologruto, T. A., Sabatini, B. L., & Svoboda, K.
- Venue
- BioMedical Engineering OnLine
- Published
- 2003-05-17
- Volume
- 2
- Issue
- 1
- Pages
- 13-13
- ISSN
- 1475-925X (ISSN-L)
- OpenAlex
- W2121071682
- Cited by
- 1,294
- References
- 2
- FWCI
- 6.61
- Type
- journal article
- Language
- en
- Open access
- gold
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