Economic and biological costs of cardiac imaging
Open accessAbstract
Medical imaging market consists of several billion tests per year worldwide. Out of these, at least one third are cardiovascular procedures. Keeping in mind that each test represents a cost, often a risk, and a diagnostic hypothesis, we can agree that every unnecessary and unjustifiable test is one test too many. Small individual costs, risks, and wastes multiplied by billions of examinations per year represent an important population, society and environmental burden. Unfortunately, the appropriateness of cardiac imaging is extra-ordinarily low and there is little awareness in patients and physicians of differential costs, radiological doses, and long term risks of different imaging modalities. For a resting cardiac imaging test, being the average cost (not charges) of an echocardiogram equal to 1 (as a cost comparator), the cost of a CT is 3.1x, of a SPECT 3.27x, of a Cardiovascular Magnetic Resonance imaging 5.51x, of a PET 14.03x, and of a right and left heart catheterization 19.96x. For stress cardiac imaging, compared with the treadmill exercise test equal to 1 (as a cost comparator), the cost of stress echocardiography is 2.1x and of a stress SPECT scintigraphy is 5.7x. Biohazards and downstream long-term costs linked to radiation-induced oncogenesis should also be considered. The radiation exposure is absent in echo and magnetic resonance, and corresponds to 500 chest x rays for a sestamibi cardiac stress scan and to 1150 chest x rays for a thallium scan. The corresponding extra-risk in a lifetime of fatal cancer is 1 in 2000 exposed patients for a sestamibi stress and 1 in 1000 for a thallium scan. Increased awareness of economic, biologic, and environmental costs of cardiac imaging will hopefully lead to greater appropriateness, wisdom and prudence from both the prescriber and the practitioner. In this way, the sustainability of cardiac imaging will eventually improve.
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Detection of structural heart diseases has traditionally required advanced cardiac imaging, including echocardiography and cardiac magnetic resonance imaging, which are resource-intensive and not suitable for large-scale disease screening.
“The detection of these disorders has traditionally required advanced cardiac imaging, including echocardiography and cardiac magnetic resonance imaging, which are resource-intensive and, therefore, not suitable for large-scale disease screening.2,3”
From Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images (2025) · cites this paper as [2]
The section “The cost of cardiac imaging” reports costs for echocardiography and cardiovascular magnetic resonance imaging, supporting the claim that these tests use substantial resources. It does not say that detecting structural heart disease traditionally required them or that they are unsuitable for large-scale screening; it also notes a cost-effective example of ultrasound screening for a different condition. No page numbers are available in our copy. (LLM, conf=0.85)
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Cites
Medical professionalism in the new millennium: a physician charter
(2002) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(02)02082-3 · Cited by 1,021 · see citing works
Flagged first, then by citations
Research works printed but not linked: 26
- Roelandt J Sutherland GR Hugenholtz PG The 1980 Renaissance in the cardiac imaging: the role of ultrasound Eur Heart J 1989 10 680 683 2792110
- National Research Council [U.S.] Committee on Biological Effects of Ionizing Radiations Health effects of exposure to low levels of ionizing radiation: BEIR V/Committee on Biological Effects of Ionizing Radiations Board of Radiation Effects Research, Commission on Life Science, National Research Council 1990 Washington, DC: National Academy Press
- Lown B A Cardiologist's Perspective on the Crisis and Challenges of Biotechnology Based on an address delivered at the 5th International Heart Health Conference in Milan, Italy June 16, 2004
- Herzog P Rieger CT Risk of cancer from diagnostic X-rays Lancet 2004 363 340 341 15070557 10.1016/S0140-6736(04)15470-6 · DOI
- Multicentre aneurysm screening study [MASS] Cost effectiveness analysis of screening for abdominal aortic aneurysms based on four year results from randomised controlled trial British Medical Journal 2002 325 1135 12433761 PMC133450
- Pennell DJ Sechtem UP Higgins CB Manning WJ Pohost GM Rademakers FE van Rossum AC Shaw LJ Yucel EK Society for Cardiovascular Magnetic Resonance; Working Group on Cardiovascular Magnetic Resonance of the European Society of Cardiology Clinical indications for cardiovascular magnetic resonance [CMR]: Consensus Panel report Eur Heart J 2004 25 1940 1965 15522474 10.1016/j.ehj.2004.06.040 · DOI
- Gibbons RJ Abrams J Chatterjee K Daley J Deedwania PC Douglas JS Ferguson TB Jr Fihn SD Fraker TD Jr Gardin JM O'Rourke RA Pasternak RC Williams SV American College of Cardiology; American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable Angina) ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-summary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines J Am Coll Cardiol 2003 41 159 168 12570960 10.1016/S0735-1097(02)02848-6 · DOI
- International Commission on Radiation Protection Radiation and your patient: a guide for medical practitioners. A web module produced by Committee 3 of the International Commission on Radiological Protection 2001 United Kingdom: Pergamon Press
- International Commission on Radiological Protection Radiological protection in in Biomedical Research 1991 United Kingdom: Pergamon press 1845339
- Regulla D Griebel J Nosske D Bauer B Brix G Acquisition and assessment of patient exposure in diagnostic radiology and nuclear medicine Z Med Phys 2003 13 127 135 12868339
- Picano E Sustainability of medical imaging. Education and Debate BMJ 2004 328 578 580 15001510 10.1136/bmj.328.7439.578 PMC381057 · DOI
- Berrington de Gonzalez A Darby S Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries The Lancet 2004 363 345 51 15070562 10.1016/S0140-6736(04)15433-0 · DOI · Paper page
- Picano E. Risk of cancer from diagnostic X-rays. Letter The Lancet 2004 363 1909 1910 15183641 10.1016/S0140-6736(04)16373-3 · DOI
- Finestone A Schlesinger T Amir H Richter E Milgrom C Do physicians correctly estimate radiation risks from medical imaging? Arch Environ Health 2003 58 59 61 12747521
- Shiralkar S Rennie A Snow M Galland RB Lewis MH Gower-Thomas K Doctors' knowledge of radiation exposure: questionnaire study BMJ 2003 327 371 2 12919987 10.1136/bmj.327.7411.371 PMC175104 · DOI
- Lee CI Haims AH Monico EP Brink JA Forman HP Diagnostic CT scans: assessment of patient, physician, and radiologist awareness of radiation dose and possible risks Radiology 2004 231 393 398 15031431
- Jacob K Vivian G Steel JR X-ray dose training: are we exposed to enough? Clin Radiol 2004 59 928 934 15451354 10.1016/j.crad.2004.04.020 · DOI
- Correia MJ Hellies A Ghelarducci B Picano E Lack of Radiological Awareness in a Tertiary Care Cardiological Centre Int J Cardiol 2005 100 354 358 16098394
- Lattanzi F Magnani M Cortigiani L Mandorla S Zuppiroli A Evaluation of appropriateness of prescribing echocardiography Italian Heart J 2002 3 613 618 12116810
- Brenner DJ Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer Radiology 2004 231 440 445 15128988
- Hall EJ Radiobiology for the Radiologist 2000 5 Lippincott Williams & Wilkins, Philadelphia PA
- Hirshfeld JW Jr Balter S Brinker JA Kern MJ Klein LW Lindsay BD Tommaso CL Tracy CM Wagner LK ACCF/AHA/HRS/SCAI Clinical Competence Statement on Physician Knowledge to Optimize Patient Safety and Image Quality in Fluoroscopically Guided Invasive Cardiovascular Procedures: A Report of the American College of Cardiology Foundation/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training Circulation 2005 111 511 532 15687141 10.1161/01.CIR.0000157946.29224.5D · DOI
- Mieres JH Shaw LJ Arai A Budoff MJ Flamm SD Hundley WG Marwick TH Mosca L Patel AR Quinones MA Redberg RF Taubert KA Taylor AJ Thomas GS Wenger NK Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, Council on Cardiovascular Radiology and Intervention, American Heart Association Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease: consensus statement from the Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, Council on Cardiovascular Radiology and Intervention, American Heart Association Circulation 2005 111 682 696 15687114 10.1161/01.CIR.0000155233.67287.60 · DOI
- Picano E Informed consent and communication of risk from radiological and nuclear medicine examinations. Education and debate BMJ 2004 329 678 681 10.1136/bmj.329.7470.849 PMC521582 15472270 · DOI
- Council Directive 97/43/Euratom of 30 June 1997 on health protection of individuals against the dangers of ionising radiation in relation to medical exposure, and repealing Directive 84/466/Euratom Official Journal of the European Communities L 180 0022 0027 09/07/1997
- Picano E Stress echocardiography: a historical perspective. [Special Article] Am J Med 2003 114 126 130 12586232 10.1016/S0002-9343(02)01427-4 · DOI
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Dhingra, L. S., Aminorroaya, A., Sangha, V., Pedroso, A. F., Shankar, S. V., Coppi, A., Foppa, M., Brant, L. C. C., Barreto, S. M., Ribeiro, A. L. P., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.01.030 · Cited by 53 · see citing works
- Authors
- Picano, E.
- Affiliations
- Istituto di Fisiologia Clinica (IT)
- Corresponding author
- Picano, Eugenio
- Venue
- Cardiovascular Ultrasound
- Published
- 2005-05-25
- Volume
- 3
- Issue
- 1
- Pages
- 13-13
- ISSN
- 1476-7120 (ISSN-L)
- PMC
- PMC1166568
- OpenAlex
- W1484599032
- Cited by
- 96
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 4 · 2017: 5 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 5 · 2012: 5
- FWCI
- 7.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cardiovascular Ultrasound (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Health Professions › General Health Professions › Healthcare cost, quality, practices
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
- Keywords
- cardiac imaging, appropriateness of imaging, unnecessary testing, radiation-induced cancer risk, radiation dose, stress echocardiography, stress SPECT, cardiovascular magnetic resonance, PET, cardiac catheterization, treadmill exercise testing, thallium scintigraphy, sestamibi scintigraphy
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