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Effects of Zinc Magnesium Aspartate (ZMA) Supplementation on Training Adaptations and Markers of Anabolism and Catabolism
Open accessAbstract
This study examined whether supplementing the diet with a commercial supplement containing zinc magnesium aspartate (ZMA) during training affects zinc and magnesium status, anabolic and catabolic hormone profiles, and/or training adaptations. Forty-two resistance trained males (27 +/- 9 yrs; 178 +/- 8 cm, 85 +/- 15 kg, 18.6 +/- 6% body fat) were matched according to fat free mass and randomly assigned to ingest in a double blind manner either a dextrose placebo (P) or ZMA 30-60 minutes prior to going to sleep during 8-weeks of standardized resistance-training. Subjects completed testing sessions at 0, 4, and 8 weeks that included body composition assessment as determined by dual energy X-ray absorptiometry, 1-RM and muscular endurance tests on the bench and leg press, a Wingate anaerobic power test, and blood analysis to assess anabolic/catabolic status as well as markers of health. Data were analyzed using repeated measures ANOVA. Results indicated that ZMA supplementation non-significantly increased serum zinc levels by 11 - 17% (p = 0.12). However, no significant differences were observed between groups in anabolic or catabolic hormone status, body composition, 1-RM bench press and leg press, upper or lower body muscular endurance, or cycling anaerobic capacity. Results indicate that ZMA supplementation during training does not appear to enhance training adaptations in resistance trained populations.
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“Wilborn et al. [416] had resistance trained males ingest a ZMA supplement or placebo in a double-blind fashion and resistance train for 8 weeks and found no change in free or total testosterone, strength or fat-free mass (via DXA).”
From ISSN exercise & sports nutrition review update: research & recommendations (2018) · cites this paper as [416]
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ISSN exercise & sports nutrition review update: research & recommendations
Kerksick, C. M., Wilborn, C. D., Roberts, M. D., Smith-Ryan, A., Kleiner, S. M., Jäger, R., Collins, R., Cooke, M., Davis, J. N., Galvan, E., et al. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0242-y · Cited by 945
Self-citationISSN exercise & sport nutrition review: research & recommendations
Kreider, R. B., Wilborn, C. D., Taylor, L., Campbell, B., Almada, A. L., Collins, R., Cooke, M., Earnest, C. P., Greenwood, M., Kalman, D. S., et al. (2010) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-7-7 · Cited by 428
Self-citationZinc at the crossroads of exercise and proteostasis
Hernández‐Camacho, J. D., Vicente‐García, C., Parsons, D. S., & Navas‐Enamorado, I. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101529 · Cited by 107
Nutrient and Stress Management
Singh, K. (2016) · Journal of Nutrition & Food Sciences · doi:10.4172/2155-9600.1000528 · Cited by 82
Dietary vs. pharmacological doses of zinc: A clinical review
Santos, H. O., Teixeira, F. J., & Schoenfeld, B. J. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.06.024 · Cited by 77
Metadata
- Authors
- Wilborn, C. D., Kerksick, C. M., Campbell, B. I., Taylor, L. W., Marcello, B. M., Rasmussen, C. J., Greenwood, M. C., Almada, A., & Kreider, R. B.
- Affiliations
- Baylor University (US)
- IMAGINutrition Laguna Nigel CA USA
- Corresponding author
- Kreider, Richard B
- ORCID
- Venue
- Journal of the International Society of Sports Nutrition
- Publisher
- Informa UK Limited
- Published
- 2004-12-01
- Volume
- 1
- Issue
- 2
- Pages
- 12-20
- ISSN
- 1550-2783 (ISSN-L)
- PMC
- PMC2129161
- OpenAlex
- W2171295217
- Cited by
- 45
- References
- 18
- Citations by year
- 2025: 1 · 2024: 5 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 2 · 2013: 2 · 2012: 2
- FWCI
- 0.13
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Journal of the International Society of Sports Nutrition (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Ohio State University
- Baylor University
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Keywords
- dietary supplementation, resistance training, training effects, zinc status, magnesium status, anabolic hormones, catabolic hormones, body composition, muscular endurance, anaerobic power, resistance-trained men
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