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Development of a quality assessment tool for systematic reviews of observational studies (QATSO) of HIV prevalence in men having sex with men and associated risk behaviours
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Background: Systematic reviews based on the critical appraisal of observational and analytic studies on HIV prevalence and risk factors for HIV transmission among men having sex with men are very useful for health care decisions and planning. Such appraisal is particularly difficult, however, as the quality assessment tools available for use with observational and analytic studies are poorly established. Methods: We reviewed the existing quality assessment tools for systematic reviews of observational studies and developed a concise quality assessment checklist to help standardise decisions regarding the quality of studies, with careful consideration of issues such as external and internal validity. Results: A pilot version of the checklist was developed based on epidemiological principles, reviews of study designs, and existing checklists for the assessment of observational studies. The Quality Assessment Tool for Systematic Reviews of Observational Studies (QATSO) Score consists of five items: External validity (1 item), reporting (2 items), bias (1 item) and confounding factors (1 item). Expert opinions were sought and it was tested on manuscripts that fulfil the inclusion criteria of a systematic review. Like all assessment scales, QATSO may oversimplify and generalise information yet it is inclusive, simple and practical to use, and allows comparability between papers. Conclusion: A specific tool that allows researchers to appraise and guide study quality of observational studies is developed and can be modified for similar studies in the future.
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“The need for complete reporting of all relevant methodological aspects as a prerequisite to assessing the risk of bias of studies was highlighted in 10 articles, [16, 33, 35, 47, 50, 56, 86, 87, 90, 91] and was the focus of recommendations in a publication from the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group [12].”
From Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations (2018) · cites this paper as [86]
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Metadata
- Authors
- Wong, W. C., Cheung, C. S., & Hart, G. J.
- Affiliations
- The University of Melbourne (AU)
- Chinese University of Hong Kong (HK)
- Mortimer Market Centre (GB)
- Corresponding author
- Wong, William CW
- Venue
- Emerging Themes in Epidemiology
- Published
- 2008-11-17
- Volume
- 5
- Issue
- 1
- Pages
- 23-23
- ISSN
- 1742-7622 (ISSN-L)
- PMC
- PMC2603000
- OpenAlex
- W2161763362
- Cited by
- 257
- References
- 15
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 12 · 2023: 15 · 2022: 13 · 2021: 18 · 2020: 22 · 2019: 15 · 2018: 16 · 2017: 28 · 2016: 22 · 2015: 24 · 2014: 17 · 2013: 19 · 2012: 19
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Emerging Themes in Epidemiology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- Open Scholarship Institutional Repository (Washington University in St. Louis) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- Funders
- Chinese University of Hong Kong
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- quality assessment tools, systematic reviews, observational studies, HIV prevalence, men who have sex with men, HIV risk behavior, generalizability, internal validity, reporting quality, bias, confounding, critical appraisal
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