A prospective study of the psychobehavioral factors responsible for a change from non-patient irritable bowel syndrome to IBS patient status
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BACKGROUND: To investigate non-patient irritable bowel syndrome (IBS) change to IBS and to determine factors predictive of the onset of IBS, individual biological factors, psychological factors, behavioral factors, and environmental factors were examined. METHODS: The subjects were 105 non-patient IBS (male = 59, female = 46, average age:21.49 +/- 2.37), including 68 of the diarrhea-predominant type and 37 of the constipation-predominant type selected from 1,409 university and technical college students by use of a questionnaire based on the Rome II diagnostic criteria. The subjects were followed for three years, and various characteristics and IBS symptoms were serially observed (12 times). The IBS incidence rate was calculated. RESULTS: During the three years, 37 non-patient IBS (35.24%) changed to IBS: 28 diarrhea-predominant type and 9 constipation-predominant type. All IBS symptoms disappeared in 26 non-patient IBS subjects (24.76%). According to quantification method II (discriminant analysis), seven factors (stressor, two kinds of stress coping styles, cognitive appraisal, eating habits, sleeping time, and psychologically abuse) were adopted as a predictive model for IBS incidence and were confirmed as predictive of IBS. CONCLUSION: The results of this research show that non-patient IBS is a changeable state that can change into IBS or persons without symptoms. Most of the non-patient IBS subjects who became asymptomatic had had symptoms for six months or less. Furthermore, the longer a non-patient IBS subject had symptoms, the higher the risk of a change to IBS became. The findings suggest the usefulness of identifying and approaching non-patient IBS as early as possible to prevent the onset of IBS. It must be noted that the persons surveyed in the present study had only the diarrhea-predominant and constipation-predominant types. Therefore, the findings of the present study are limited only these two types. Further study including the mixed type is needed.
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About 30% of IBS non-patients become IBS patients within three years.
“Although treatment for IBS non-patients is needed because about 30% of IBS non-patients become IBS patients within three years (Fujii & Nomura, 2008), many psychological treatments for IBS only target patients with severe symptoms.”
From Effectiveness of acceptance and commitment therapy for irritable bowel syndrome non-patients: A pilot randomized waiting list controlled trial (2020) · cites this paper as Fujii & Nomura, 2008
The Results (‘Changes in non-patient IBS over 3-years of follow-up’) report that 37 of 105 non-patient IBS subjects (35.24%) became IBS patients within three years, broadly supporting ‘about 30%.’ The citing sentence presents this as a rate for IBS non-patients generally, whereas the paper says its findings are limited to diarrhea- and constipation-predominant types, and the Discussion notes that nearly all subjects were students. (LLM, conf=0.85)
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Self-citation
- Authors
- Fujii, Y., & Nomura, S.
- Affiliations
- Waseda University (JP)
- Corresponding author
- Fujii, Yasushi
- ORCID
- Nomura, Shinobu
- Venue
- BioPsychoSocial Medicine
- Published
- 2008-09-25
- Volume
- 2
- Issue
- 1
- Pages
- 16-16
- ISSN
- 1751-0759 (ISSN-L)
- PMC
- PMC2564973
- OpenAlex
- W2132999617
- Cited by
- 24
- References
- 28
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 4 · 2022: 1 · 2021: 1 · 2019: 4 · 2017: 3 · 2016: 4 · 2015: 1 · 2012: 1
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BioPsychoSocial Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Health Professions › Pharmacy › Infant Health and Development
- Keywords
- irritable bowel syndrome, stress coping styles, psychological stress, cognitive appraisal, dietary habits, sleep duration, psychological violence, university students
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