The DOI matches its Crossref record; 202 of the 202 references it cites were found in a registry or an index.
Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part II – contemporary contextual research
Open accessAbstract
In recent years there has been a renewed interest concerning the ways in which the gastrointestinal tract – its functional integrity and microbial residents – might influence human mood (e.g. depression) and behavioral disorders. Once a hotbed of scientific interest in the early 20th century, this area lay dormant for decades, in part due to its association with the controversial term ‘autointoxication’. Here we review contemporary findings related to intestinal permeability, small intestinal bacterial overgrowth, lipopolysaccharide endotoxin (LPS) exposure, D-lactic acid, propionic acid, and discuss their relevance to microbiota and mental health. In addition, we include the context of modern dietary habits as they relate to depression, anxiety and their potential interaction with intestinal microbiota.
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“These rodent studies suggest that the gut microbiome has strategic evolutionary importance by modulating stress responses and influencing behaviors that impact the survival of species.15”
From The Gut Microbiome and the Brain (2014) · cites this paper as [15]
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“The adult human gut is believed to contain about one gram of LPS.15”
From The Gut Microbiome and the Brain (2014) · cites this paper as [15]
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Cited by
Sorted by citations
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
Rogers, G. B., Keating, D. J., Young, R. L., Wong, M.-L., Licinio, J., & Wesselingh, S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.50 · Cited by 969
The Gut Microbiome and the Brain
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Kazemi, A., Noorbala, A. A., Azam, K., Eskandari, M. H., & Djafarian, K. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2018.04.010 · Cited by 534
Microbes, immunity, and behavior: psychoneuroimmunology meets the microbiome
Dinan, T. G., & Cryan, J. F. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.103 · Cited by 246
Gut Microbiota: The Conductor in the Orchestra of Immune–Neuroendocrine Communication
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Metadata
- Authors
- Bested, A. C., Logan, A. C., & Selhub, E. M.
- Affiliations
- B.C. Women's Hospital & Health Centre (CA)
- Harvard University (US)
- Corresponding author
- Logan, Alan C
- ORCID
- Logan, Alan C
- Venue
- Gut Pathogens
- Published
- 2013-03-14
- Volume
- 5
- Issue
- 1
- Pages
- 3-3
- ISSN
- 1757-4749 (ISSN-L)
- PMC
- PMC3601973
- OpenAlex
- W2118613385
- Cited by
- 121
- References
- 202
- Citations by year
- 2026: 1 · 2025: 11 · 2024: 6 · 2023: 7 · 2022: 13 · 2021: 6 · 2020: 9 · 2019: 8 · 2018: 13 · 2017: 10 · 2016: 12 · 2015: 15 · 2014: 6 · 2013: 3
- FWCI
- 5.38
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Gut Pathogens (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- gut microbiota, probiotics, gut-brain axis, depression, anxiety, mental health, intestinal permeability, small intestinal bacterial overgrowth, D-lactate, propionic acid, autointoxication, dietary habits
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