Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

Cited by (386)

Items 301–386 of 386

1. Decoding Gene Regulation in Alzheimer’s Disease with Transfer Learning and Explainable Machine Learning
   Sergio Peignier, Amanda Lo Van, Yann Meunier, Elea Pauliat, Matis Zouari, Federica Calevro · 2025 · Lecture notes in computer science
2. Multilevel white matter degeneration associated cognitive dysfunction in mild cognitive impairment
   Yu Chen, Tian-Tian Liu, Li-Zhi Cao, Li Wang, Shintaro Funahashi, Xiao-Ying Tang, Jing-Long Wu, W. Meng, Jian Zhang, Tian-Yi Yan · 2025 · Molecular Psychiatry
3. Impact of Lewy body and limbic-predominant TDP-43 neuropathology on cognitive and neuropsychiatric trajectory in Alzheimer’s disease: a retrospective neuropathological study
   Jarok Koo, H.S. Lee, Yoo Shin Choi, Kyoungwon Baik, Mincheol Park, Alzheimer’s Disease Neuroimaging Initiative · 2026 · Frontiers in Aging Neuroscience
4. Deep multimodal learning for domain-level cognitive decline prediction in Alzheimer's disease
   Fernando García-Gutierrez, J. Matias-Guiu, J. L. Ayala · 2025 · Frontiers Artif. Intell.
5. Altered Microglia-Neuron Crosstalk and Regional Heterogeneity in Alzheimer’s Disease Revealed by Single-Nucleus RNA Sequencing
   Zhenqi Yang, Mingzhao Zhang, Weijia Zhi, Lizhen, Xiangjun Hu, Yong Zou, Lifeng Wang · 2026 · International Journal of Molecular Sciences
6. Mapping heterogeneous brain structural subtypes in alzheimer’s disease and mild cognitive impairment using normative models
   Xiaotong Wei, Tingting Zhang, Ronglong Xiong, Qiuzhu Zhang, Junjun Zhang, Zhenlan Jin, Ling Li · 2026 · Translational Psychiatry
7. Cerebrospinal Fluid Biomarkers of Preclinical Alzheimer’s Disease
   Panagiotis Alexopoulos, Chaido Sirinian · 2018 · Neuromethods
8. Prediction of Conversion to Alzheimer’s Disease Using 3D-DWT and PCA
   Aow Yong Li Yew, Mohd Shafry Mohd Rahim, Chi Wee Tan · 2022 · Lecture notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
9. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia
   Abhilasha Ahlawat, Vaibhav Walia, Munish Garg · 2022 · Springer eBooks
10. Disambiguation of Cognitive Impairment Diagnosis with EEG-Based Dual-Contrastive Learning
    Zhenxi Song, Zian Pei, Huixia Ren, Lin Zhu, Yi Guo, Zhiguo Zhang · 2023 · IEEE International Conference on Acoustics Speech and Signal Processing
11. Revealing the heterogeneity of plasma protein and cognitive decline trajectory among Mild Cognitive Impairment patients by clustering of brain atrophy features
    My Nguyen, Bao Hoai Pham, Vo Van Toi, Huong Ha · 2024 · Brain Multiphysics
12. VasCog 2023: 20 years of research on vascular behavioural and cognitive disorders
    D.R. Gustafson, Raj N. Kalaria, John Tiernan O'Brien, Hilde van den Brink, Saima Hilal, Anna Marseglia, Annemieke ter Telgte, Ingmar Gr. Skoog · 2024 · Cerebral Circulation - Cognition and Behavior
13. Mixture Disease Progression Model to Predict and Cluster the Long-Term Trajectory of Cognitive Decline in Alzheimer’s Disease
    R. Hanazawa, H. Sato, Akihiro Hirakawa · 2024 · Therapeutic Innovation and Regulatory Science
14. Usage of the MMSE obscures the science of dementia
    Eugen Tarnow · 2017 · Geriatric Medicine and Care
15. Verbal and Nonverbal Memory in Neurodegenerative and Stroke Aphasia: Evidence From the Turkish Version of the Three Words Three Shapes Test
    Mustafa Seckin, Begüm Özbek, İlayda Demir, Elif Kurt, Ulaş Ay, Düzgün Yildirim, Nilüfer Yeşilot, Oğuzhan Çoban, Öget Öktem, Hakan I. Gurvit · 2022 · Cognitive and Behavioral Neurology
16. Depression in Alzheimer's disease : biomarkers and treatment
    Daniela Enache · 2015 · Figshare
17. Modelling the Neuroanatomical Progression of Alzheimer's Disease and Posterior Cortical Atrophy
    Razvan Valentin Marinescu · 2020 · arXiv (Cornell University)
18. Differential Brain Atrophy Patterns and Neurogenetic Profiles in Cognitively-Defined Alzheimer’s Disease Subgroups
    Colin Groot, Michel J. Grothe, Shubhabrata Mukherjee, Irina Jelistratova, Iris E. Jansen, Anna Catharina van Loenhoud, Shannon L. Risacher, Andrew J. Saykin, Christine L. Mac Donald, Jesse B Mez et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
19. Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burden
    Samuel J. Brunwasser, James N. McGregor, Kiran Bhaskaran‐Nair, Clayton A. Farris, Halla Elmore, Eva L. Dyer, John M. Grady, Jennifer D. Whitesell, Julie A. Harris, Keith B. Hengen · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
20. Brain Cell-based Genetic Subtyping and Drug Repositioning for Alzheimer Disease
    Nathan J Sahelijo, Priya Rajagopalan, Qian Lu, Rufuto Rahman, Dhawal Priyadarshi, Daniel Goldstein, Sophia I. Thomopoulos, David A. Bennett, Lindsay A. Farrer, Thor D. Stein et al. · 2024 · medRxiv
21. Bisdemethoxycurcumin mitigates Alzheimer disease pathology through autophagy-mediated reduction of senescence and amyloid beta
    Parul Khajuria, Dilpreet Kour, Kuhu Sharma, Lakhvinder Singh, Razia Banoo, Diksha Manhas, P. Ramajayan, Utpal Nandi, Sandip Bibishan Bharate, Zabeer Ahmed et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
22. Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions
    Camille Elleaume, Bruno Hebling Vieira, Dorothea L. Floris, Nicolas Langer, the Australian Imaging Biomarkers and Lifestyle flagship study of ageing · 2025 · eLife
23. Abeta(1-42) enhances neuronal excitability and disrupts synaptic plasticity by altering glutamate-recycling
    Edina Varga · 2015
24. Potential Animal Models of Alzheimer Disease and Their Importance in Investigating the Pathogenesis of Alzheimer Disease
    A. A. Farooqui · 2016 · Springer eBooks
25. Investigating Simulated Driving Behaviour and Brain Activation in Mild Cognitive Impairment
    Megan A. Hird · 2016 · TSpace (University of Toronto)
26. Biomarkers of Alzheimer’s Disease
    Usman Saeed, Walter Swardfager, Sandra E. Black, Mario Masellis · 2017 · Mental health and illness worldwide
27. EFFECTS OF THE NOVEL IDO INHIBITOR DWG-1036 ON THE BEHAVIOUR AND NEUROCHEMISTRY OF THE TRIPLE TRANSGENIC MOUSE MODEL OF ALZHEIMER’S DISEASE
    Emre Fertan · 2017 · DalSpace (Dalhousie University)
28. Apolipoprotein E polymorphism and hippocampal atrophy across the spectrum of Alzheimer’s disease and dementia with Lewy bodies
    Usman Saeed · 2018 · TSpace (University of Toronto)
29. Amyloid beta: from pre-analytical factors to disease mechanisms
    Jamie Toombs · 2019 · UCL Discovery (University College London)
30. Characterization of microglial Rab7 knockout on amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
    Beate Maren Erika Koch · 2019
31. »Man kennt nur die Dinge, die man zähmt«
    Rolf Dieter Hirsch · 2017 · Psychotherapie im Alter
32. Investigating the Effect of Mild Cognitive Impairment on Brain Activity during Completion of the Clock-drawing Test
    Natasha A. Talwar · 2019 · TSpace (University of Toronto)
33. Transcriptome Meta-Analysis Suggests the Existence of Two Molecular Subtypes in Alzheimer’s Disease
    Anahita Nazari, Sayed‐Amir Marashi, Hesam Montazeri · 2021 · Research Square
34. Polygenic Risk Score Effectively Predicts Risk of Depression Onset in Alzheimer’s Disease
    Suraj Upadhya, Hongliang Liu, Sheng Luo, Michael William Lutz, Ornit Chiba‐Falek · 2021 · Research Square
35. The influence of industrialism on French imaginative literature, prose, 1830-70
    William Harley · 1952 · Durham e-Theses (Durham University)
36. Perspective Chapter: Alzheimer - A Complex Genetic Background
    Marco Calabrò, Concetta Crisafulli · 2022 · IntechOpen eBooks
37. Faculty Opinions recommendation of Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's disease.
    John Wesson Ashford · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
38. Faculty Opinions recommendation of Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
    Stefano Francesco Cappa · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
39. Brain cross-omics integration in Alzheimer’s disease
    Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano‐Tárraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann et al. · 2022 · medRxiv
40. Munkánk értelmét és a reményt a közös küzdelem adja : Szabó Lajos Időskori demenciák családi, társadalmi és pszichológiai vonatkozásai című könyvéről
    Csaba Madár · 2022 · Máltai Tanulmányok
41. Patient-specific multi-modal modeling uncovers neurotransmitter receptor involvement in motor and non-motor axes of Parkinson’s disease
    Ahmed Faraz Khan, Quadri Adewale, Sue‐Jin Lin, Tobias R. Baumeister, Yashar Zeighami, Félix Carbonell, Nicola Palomero‐Gallagher, Yasser Iturria‐Medina · 2023 · medRxiv
42. Clinical and biochemical markers of neurodegenerative process in Alzheimer's disease
    Н. Г. Жукова, Elena Kolupaeva, Irina A. Zhukova, O. Izhboldina, A.Ya. Masenko · 2023 · Vestnik nevrologii psihiatrii i nejrohirurgii (Bulletin of Neurology Psychiatry and Neurosurgery)
43. Heteroscedastic Personalized Regression Unveils Genetic Basis of Alzheimer’s Disease Stratified by Cognitive Level
    Zhirong Chen, Haohan Wang · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
44. Early Event-Related Potential components as potential biomarkers for Alzheimer's Disease and their relationship with attentional capacity.
    Duncan Morison · 2023
45. Encoding and decoding multimodal brain images for disease biomarker discovery
    Yi Hao Chan · 2023
46. Klinik Nöroloji
    Mehmet Türkay Karcı, Erdem Özyurt, Merve Bahar Ercan, Safiye Gül Kenar, Filiz Demirdöğen, Betül Özenç, Özlem Ergin Beton, Nur Türkmen, Mustafa Şen, Mustafa Açıkgöz et al. · 2022 · Akademisyen Kitabevi eBooks
47. The Construct of Alzheimer’s Disease Matured for Retirement
    Pavel Kalvach · 2024 · International Journal of Geriatrics and Gerontology
48. Adaptive Subtype and Stage Inference for Alzheimer’s Disease
    Xinkai Wang, Yonggang Shi · 2024 · Lecture notes in computer science
49. Unraveling Alzheimer's disease heterogeneity:
    Eleonora M. Vromen · 2024
50. A signal processing and machine learning pipeline for the analysis of spectral fluorescence data from stained brain tissue samples in Alzheimer's disease and normal aging
    Anastasiia A. Stepanchuk, Jeffrey T. Joseph, Peter K. Stys · 2025 · Advanced Chemical Microscopy for Life Science and Translational Medicine
51. The Rehab Reco—A Therapy Recommender System for Dementia
    Pritish Pore, Sharvari Bhagwat, Yash Desai, Prutha Rinke, Arati R. Deshpande, Soubhik Das, Pushkraj Marne · 2025 · Lecture notes in electrical engineering
52. Frontal Variant Alzheimer’s Disease or Primary Psychiatric Disorder? A Case Report
    Siew Fai Liew, Wei-Shan Li · 2025 · Reports
53. Adherence to lifestyle intervention activities in the SINgapore GERiatric to reduce cognitive decline and physical frailty (SINGER) study: A one-year preliminary analysis of process evaluation
    Kwong Hsia Yap, April Ka Sin Phua, Richelle Santiano, Melmar Cerilo Folloso, Eddie Jun Yi Chong, Xinyi Xu, Christiani Jeyakumar Henry, Effie Chew, Andrea Britta Maier, Nagaendran Kandiah et al. · 2025 · Patient Education and Counseling
54. Structural Similarity Networks Reveal Brain Vulnerability in Dementia
    Marcella Montagnese, Amir Ebneabbasi, Natalia García-San-Martín, Clara Pecci-Terroba, Rafael Romero-García, Sarah Elizabeth Morgan, James Howard Cole, Jakob Seidlitz, Timothy Rittman, Richard A. I. Bethlehem · 2025 · medRxiv
55. Cardiovascular Risk as a Moderator of the Relationship of Plasma Alzheimer’s Disease Biomarkers with Cognitive Status
    Angelina Kirilova Kancheva, Donald Lyall, Kamen A. Tsvetanov, Ivana Kirilova Kancheva, Kalliopi Mavromati, Ivan G. Koychev, Benjamin Tari, Daniela Jaime García, Lynne Hughes, Joanna Marguerite Wardlaw et al. · 2025 · medRxiv
56. Optimizing the Color Shapes Task for Ambulatory Assessment and Drift Diffusion Modeling: A Factorial Experiment
    Sharon Haeun Kim, Jonathan George Hakun, Yanling Li, Karra Harrington, Daniel Elbich, Martin J. Sliwinski, Joachim Vandekerckhove, Zita Oravecz · 2025 · JMIR Formative Research
57. Modeling the Heterogeneity and Trajectories of Cognitive Dysfunction in Parkinson’s Disease Using Partially Ordered Set Models
    Cole Zweber, Judith Jaeger, Cyrus P. Zabetian, Rebecca Miller, Vivikta Iyer, Amie Hiller, Satya Sanket Sahoo, Brenna Cholerton, Abigail Ryan, Curtis M. Tatsuoka et al. · 2025 · medRxiv
58. Multiscale convolution-attention model for efficient Alzheimer’s disease and mild cognitive impairment diagnosis approach using sMRI
    Uttam Khatri, Junhyung Kim, Goo‐Rak Kwon · 2025 · Applied Soft Computing
59. A$$\upbeta $$-PET Pattern Prediction via Graph Reconstruction-Aware Fusion (GRAF) of Functional and Structural Networks
    Haoyue Yuan, Yuxiao Liu, Feihong Liu, Dinggang G. Shen · 2025 · Lecture notes in computer science
60. Predicting Alzheimer’s Disease: A Case Study Using Federated Learning Framework
    Aman Sharma, Mohit Pal, Aditya Soni, Rajni Mohana · 2025 · Studies in systems, decision and control
61. Posterior Cortical Atrophy
    Zeinab Abdi, Emma Harding, Victoria Susan Pelak, Keir X. X. Yong, Sebastian James Crutch · 2025 · Cambridge University Press eBooks
62. CauReL: Dynamic Counterfactual Learning for Precision Drug Repurposing in Alzheimer's Disease
    Yanfei Wang, Minghao Zhou, Zijia Tang, Chenxi Xiong, Breton Michael Asken, Baijian Yang, Jing Su, Xiaobo Zhou, Qianqian Song · 2025 · Research Square
63. Additional file 2 of Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer’s disease pathology in Down syndrome
    Alison M. Maxwell, Peng Yuan, Brianna M. Rivera, Schaaf, Wilder, Mihovil Mladinov, Prasher, Vee P., Andrew Robinson, William F. DeGrado, Carlo Condello · 2021 · Figshare
64. Additional file 1 of Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer’s disease pathology in Down syndrome
    Alison M. Maxwell, Peng Yuan, Brianna M. Rivera, Schaaf, Wilder, Mihovil Mladinov, Prasher, Vee P., Andrew Robinson, William F. DeGrado, Carlo Condello · 2021 · Figshare
65. Additional file 1 of Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes
    Afrah Shafquat, Crystal, Ronald G., Jason G. Mezey · 2020 · Figshare
66. Additional file 1 of Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysis
    Antoinette O’Connor, Philip S.J. Weston, Ivanna M. Pavisic, Natalie Sarah Ryan, Jessica D. Collins, Kirsty Lu, Sebastian James Crutch, Daniel C. Alexander, Nick C. Fox, Neil P. Oxtoby · 2020 · Figshare
67. Unraveling the molecular links: Alzheimer's disease-induced mechanisms of memory impairment: A narrative review
    Yousef Baghcheghi, Fateme Razazpour, Mola Mohammadi, Habibeh Mashayekhi‐Sardoo, Mahdiyeh Hedayati‐Moghadam · 2026 · Journal of Alzheimer s Disease Reports
68. Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions
    Camille Elleaume, Bruno Hebling Vieira, Dorothea L. Floris, Nicolas Langer, the Australian Imaging Biomarkers and Lifestyle flagship study of ageing · 2026 · eLife
69. Diffusion MRI measures detect brain microstructure changes due to early treatment with neurotrophic peptide mimetic P021 in the 3xTg-AD mouse model of Alzheimer's disease
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70. Transmission of Alzheimer pathology in murine and primate models : from proteinopathies to neuronal and cognitive impairments
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71. Regulation of Alzheimer pathology by amyloid seeds : from toxic effects to therapeutic opportunities, in mouse model of amyloidosis
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72. Musical rhythm and synchronization in normal and pathological aging
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73. Blood–Brain Network-Based Polygenic Risk Scores Reveal Biomarker Signatures and the Progression of Alzheimer’s Disease
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74. Dissecting Alzheimer’s disease heterogeneity by cross-trait polygenic prediction
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75. Scalable CT-based prognostic modeling of dementia conversion in mild cognitive impairment
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76. Performance Analysis of FreeSurfer with Optimized Transfer Learning Model for Prediction of Multiclass Alzheimer’s Disease
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77. Utilizing routinely acquired clinical neuroimaging and electronic health record data to advance precision medicine in dementia care
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78. A Subtyping Study of Patients with Alzheimer’s Disease Based on Brain Functional Dynamics
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79. Multimodal network alterations in diagnosis-age-defined early- and late-onset Alzheimer’s disease
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80. Cerebral perfusion correlates of domain-specific cognitive function in Alzheimer's disease and dementia with Lewy bodies
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81. Atypical Alzheimer disease: a multi-axis framework toward defining heterogeneity
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82. Alzheimer’s Disease Detection Methods: Current Advancements and Future Directions
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83. The Adult Neurogenesis Theory of Alzheimer’s Disease Predicts Where Tauopathy Develops in the Brain
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84. Synergistic approaches to Alzheimer’s disease: exploring the combined efficacy of phytoconstituents and conventional drugs
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85. A cell-type-directed drug repurposing framework for Alzheimer's disease subtypes
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86. Neuropathologic features of cognitively defined Alzheimer's disease subgroups in the Adult Changes in Thought study
    Caitlin S. Latimer, Rod L. Walker, Marika Bogdani, C. Dirk Keene, Amber Nolan, Daniel D. Child, Shubhabrata Mukherjee, Seo‐Eun Choi, Michael L. Lee, Connie Y. Nakano et al. · 2026 · Alzheimer s & Dementia