Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

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Items 101–200 of 386

  1. Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History
    Félix Bermejo‐Pareja, Teodoro del Ser · 2024 · Journal of Clinical Medicine
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    F. Falahati, D. Ferreira, J.-Sebastian Muehlboeck, M. Eriksdotter, A. Simmons, L. Wahlund, E. Westman · 2017 · NeuroImage: Clinical
  3. Amyloid pathology arrangements in Alzheimer’s disease brains modulate in vivo seeding capability
    Claudia A. Duran-Aniotz, Inés Moreno‐González, Nazaret Gamez, Nelson Perez-Urrutia, Laura Vegas‐Gomez, Claudio A. Soto, Rodrigo Morales · 2021 · Acta Neuropathologica Communications
  4. Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer’s disease subgroups
    Colin Groot, Michel J. Grothe, Shubhabrata Mukherjee, Irina Jelistratova, Iris E. Jansen, Anna Catharina van Loenhoud, Shannon L. Risacher, Andrew J. Saykin, Christine L. Mac Donald, Jesse Mez et al. · 2021 · NeuroImage Clinical
  5. FRONTIER Executive Screen: a brief executive battery to differentiate frontotemporal dementia and Alzheimer’s disease
    Leslie, F V C, Foxe, D, Daveson, N, Flannagan, E, Hodges, J R, Piguet, O · 2016 · Journal of Neurology, Neurosurgery & Psychiatry
  6. Deep Learning Approaches for Early Prediction of Conversion from MCI to AD using MRI and Clinical Data: A Systematic Review
    Gelareh Valizadeh, Reza Elahi, Zahra Hasankhani, Hamidreza Saligheh Rad, Ahmad Shalbaf · 2024 · Archives of Computational Methods in Engineering
  7. The Interplay of Inflammation and Gut-Microbiota Dysbiosis in Alzheimer’s Disease: Mechanisms and Therapeutic Potential
    Hanis Nabilah Abdol Samat, Nurul Nadirah Razali, Hazlina Mahadzir, Tengku Sifzizul Tengku Muhammad, King‐Hwa Ling, Nur Izzati Mansor, Shahidee Zainal Abidin · 2025 · International Journal of Molecular Sciences
  8. ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology
    Cao, Yongliang, Xu, Haochen, Zhu, Yuanbo, Shi, Mei-Juan, Wei, Lixiang, Zhang, Jin, Cheng, Shuo, Shi, Yiqian, Tong, Haiyang, Kang, Lijing et al. · 2019 · PLOS Biology · Retracted
  9. Centenarians as Models of Resistance and Resilience to Alzheimer’s Disease and Related Dementias
    Stacy L. Andersen · 2020 · Advances in Geriatric Medicine and Research
  10. Emulate randomized clinical trials using heterogeneous treatment effect estimation for personalized treatments: Methodology review and benchmark
    Yaobin Ling, Pulakesh Upadhyaya, Luyao Chen, Xiaoqian Jiang, Yejin Kim · 2022 · Journal of Biomedical Informatics
  11. A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation
    Seung Hyun Kim, Min‐Young Noh, Hee-Jin Kim, Ki‐Wook Oh, Jinseok Park, Sang-Gon Lee, Yeonsil Moon, Young-Eun Kim, Jae Sung Bae, Hee Kyung Jin et al. · 2019 · Dementia and Neurocognitive Disorders
  12. Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysis
    Antoinette O’Connor, Philip S.J. Weston, Ivanna M. Pavisic, Natalie Sarah Ryan, Jessica D. Collins, Kirsty Lu, Sebastian James Crutch, Daniel C. Alexander, Nick C. Fox, Neil P. Oxtoby · 2020 · Alzheimer s Research & Therapy
  13. Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer’s Disease Risk
    Aseel Eid, Isha Mhatre‐Winters, Ferass M. Sammoura, Melissa K. Edler, Richard von Stein, Muhammad M. Hossain, Yoonhee Han, Miriam Lisci, Kristina Carney, Mary Konsolaki et al. · 2022 · Environmental Health Perspectives
  14. CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease
    Sun Ju Chung, Mi‐Jung Kim, Young Jin Kim, Ju‐Yeon Kim, Sooyeoun You, Eun Hye Jang, Seong Yoon Kim, Jae‐Hong Lee · 2014 · Journal of the Neurological Sciences
  15. Imaging Brain Metabolism and Pathology in Alzheimer ’s Disease with Positron Emission Tomography
    Riddle WR Claassen D · 2014 · Journal of Alzheimer’s Disease & Parkinsonism
  16. Coexisting order and disorder within a common 40-residue amyloid-β fibril structure in Alzheimer's disease brain tissue
    Ujjayini Ghosh, Wai‐Ming Yau, Robert Tycko · 2018 · Chemical Communications
  17. Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies
    Todd Eliot Golde · 2016 · Journal of Neurochemistry
  18. Comparative methods for quantifying plasma biomarkers in Alzheimer's disease: Implications for the next frontier in cerebral amyloid angiopathy diagnostics
    Ryan T. Muir, Zahinoor Ismail, Sandra E. Black, Eric Edward Smith · 2023 · Alzheimer s & Dementia
  19. Beyond the usual suspects: multi-factorial computational models in the search for neurodegenerative disease mechanisms
    Ahmed Faraz Khan, Yasser Iturria‐Medina · 2024 · Translational Psychiatry
  20. Riemannian Geometry Learning for Disease Progression Modelling
    Maxime Louis, Raphaël Couronné, Igor Koval, Benjamin Charlier, Stanley Durrleman · 2019 · Lecture notes in computer science
  21. On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseases
    Giuseppe Legname, Carlo Scialò · 2020 · Prion
  22. Sensorimotor Synchronization in Healthy Aging and Neurocognitive Disorders
    Andres von Schnehen, Lise Hobeika, Dominique Huvent‐Grelle, Séverine Samson · 2022 · Frontiers in Psychology
  23. Lexical-semantic properties of verbs and nouns used in conversation by people with Alzheimer’s disease
    Eric Williams, Catherine Theys, Megan J. McAuliffe · 2023 · PLoS ONE
  24. Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions
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  25. Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer’s disease pathology in Down syndrome
    Maxwell, Alison M., Yuan, Peng, Rivera, Brianna M., Schaaf, Wilder, Mladinov, Mihovil, Prasher, Vee P., Robinson, Andrew C., DeGrado, William F., Condello, Carlo · 2021 · Acta Neuropathologica Communications
  26. Diffusion MRI detects basal forebrain cholinergic abnormalities in the 3xTg‐AD mouse model of Alzheimer's disease
    Falangola, Maria Fatima, Nie, Xingju, Ward, Ralph, Dhiman, Siddhartha, Voltin, Joshua, Nietert, Paul J., Jensen, Jens H. · 2021 · Magnetic Resonance Imaging
  27. Improvement of Machine Learning Models’ Performances based on Ensemble Learning for the detection of Alzheimer Disease
    Selim Buyrukoğlu · 2021
  28. Association of Alzheimer’s Disease with COVID-19 Susceptibility and Severe Complications: A Nationwide Cohort Study
    Seok Jong Chung, Yoonkyung Chang, Jimin Jeon, Jae Il Shin, Tae‐Jin Song, Jinkwon Kim · 2022 · Journal of Alzheimer s Disease
  29. A guide to using functional magnetic resonance imaging to study Alzheimer's disease in animal models
    Mazen Asaad, Jin Hyung Lee · 2018 · Disease Models & Mechanisms
  30. Co-expression Network Analysis Revealing the Potential Regulatory Roles of lncRNAs in Alzheimer’s Disease
    Jiong Wu, Linhui Chen, Chaobo Zheng, Shanhu Xu, Yuhai Gao, Junjun Wang · 2019 · Interdisciplinary Sciences Computational Life Sciences
  31. Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease—From Brain Starch to Bench and Bedside
    Pawlowski, Matthias, Meuth, Sven, Duning, Thomas · 2017 · Diagnostics
  32. An Overview of Primary Dementias as Clinicopathological Entities
    Arash Salardini · 2019 · Seminars in Neurology
  33. Frontal variant of Alzheimer’s disease masquerading as behavioural-variant frontotemporal dementia: a case study comparison
    Stephanie Wong, Jessica Strudwick, Emma M. Devenney, John R. Hodges, Olivier Piguet, Fiona Kumfor · 2019 · Neurocase
  34. Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
    Harmandeep Kaur Gulati, Sushil Choudhary, Nitish Kumar, Ajaz Ahmed, Kavita Bhagat, Jatinder Vir Singh, Atamjit Singh, Ajay Kumar, Preet Mohinder Singh Bedi, Harbinder Singh et al. · 2021 · Bioorganic Chemistry
  35. The temporal lobe in typical and atypical Alzheimer disease
    Raffaella Migliaccio, Federica Cacciamani · 2022 · Handbook of clinical neurology
  36. Childhood Learning Disabilities and Atypical Dementia: A Retrospective Chart Review
    Alon Seifan, Stephanie Assuras, Edward D. Huey, Jesse B Mez, Angeliki Tsapanou, Elise Caccappolo · 2015 · PLoS ONE
  37. Effects of risk factors on the development and mortality of early- and late-onset dementia: an 11-year longitudinal nationwide population-based cohort study in South Korea
    Min Young Chun, Wonjeong Chae, Sang Won Seo, Hyemin Jang, Jihwan Yun, Duk Lyul Na, Dongwoo Kang, Jungkuk Lee, Dustin B. Hammers, Liana G. Apostolova et al. · 2024 · Alzheimer s Research & Therapy
  38. Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s disease related proteins
    Stephanie R. Oatman, Joseph S. Reddy, Zachary Quicksall, Minerva M. Carrasquillo, Xue Wang, Chia‐Chen Liu, Yu Yamazaki, Thuy Nguyen, Kimberly G. Malphrus, Michael G. Heckman et al. · 2023 · Molecular Neurodegeneration
  39. Significance and Mechanisms of P-glycoprotein in Central Nervous System Diseases
    Liangliang Huang, Binbin Li, Xiang Li, Ge Liu, Rui Liu, Jia Guo, Baohui Xu, Yunman Li, Weirong Fang · 2019 · Current Drug Targets
  40. Fluid biomarkers for diagnosing dementia: rationale and the Canadian Consensus on Diagnosis and Treatment of Dementia recommendations for Canadian physicians
    Pedro Rosa‐Neto, Ging‐Yuek Robin Hsiung, Mario Masellis, on behalf of the CCDTD4 participants · 2013 · Alzheimer s Research & Therapy
  41. Scrutinizing the Therapeutic Potential of PROTACs in the Management of Alzheimer’s Disease
    Bhatia, Shiveena, Singh, Manjinder, Singh, Tanveer, Singh, Varinder · 2023 · Neurochemical Research
  42. Thiophene‐Based Ligands: Design, Synthesis and Their Utilization for Optical Assignment of Polymorphic‐Disease‐Associated Protein Aggregates
    Linnea Björk, Therése Klingstedt, K. Peter R. Nilsson · 2023 · ChemBioChem
  43. Clinical heterogeneity of frontotemporal dementia and Parkinsonism linked to chromosome 17 caused by MAPT N279K mutation in relation to tau positron emission tomography features
    Ikeda, Aya, Shimada, Hitoshi, Nishioka, Kenya, Takanashi, Masashi, Hayashida, Arisa, Li, Yuanzhe, Yoshino, Hiroyo, Funayama, Manabu, Ueno, Yuji, Hatano, Taku et al. · 2019 · Movement Disorders
  44. Diffusion MRI detects early brain microstructure abnormalities in 2-month-old 3×Tg-AD mice
    Falangola, Maria Fatima, Nie, Xingju, Ward, Ralph, McKinnon, Emilie T., Dhiman, Siddhartha, Nietert, Paul J., Helpern, Joseph A., Jensen, Jens H. · 2020 · NMR in Biomedicine
  45. N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease
    Guido Domingo, Luisa Benussi, Claudia Saraceno, Michela Bertuzzi, Roland Nicsanu, Antonio Longobardi, Sonia Bellini, Alfredo Cagnotto, Mario Salmona, Giuliano Gb. Binetti et al. · 2021 · Frontiers in Neuroscience
  46. Short-term memory conjunctive binding in Alzheimer’s disease: A systematic review and meta-analysis.
    Mário Amore Cecchini, Mario A. Parra, Miriam G. Brazzelli, Robert H. Logie, Sergio Della Sala · 2022 · Neuropsychology
  47. Biomarker-Driven Therapeutic Management of Alzheimer’s Disease: Establishing the Foundations
    Jeffrey L. Cummings, K. Zhong · 2013 · Clinical Pharmacology & Therapeutics
  48. Validity of the QUADAS-2 in Assessing Risk of Bias in Alzheimer's Disease Diagnostic Accuracy Studies
    Alisson Venazzi, Walter Swardfager, Benjamin Lam, José de Oliveira Siqueira, Nathan Herrmann, Hugo Cogo‐Moreira · 2018 · Frontiers in Psychiatry
  49. Memory precision of object-location binding is unimpaired in APOE ε4-carriers with spatial navigation deficits
    Helena Marie Gellersen, Gillian Coughlan, Michael Hornberger, Jon S. Simons · 2021 · Brain Communications
  50. Preliminary exploration of the co-regulation of Alzheimer’s disease pathogenic genes by microRNAs and transcription factors
    Qi Zhang, Ping Yang, Xinping Pang, Wenbo Guo, Yue Sun, Yanyu Wei, Chao-Yang Pang · 2022 · Frontiers in Aging Neuroscience
  51. Mitochondrial Targeting against Alzheimer’s Disease: Lessons from Hibernation
    Christina F. de Veij Mestdagh, August Benjamin Smit, Robert H. Henning, Ronald E. van Kesteren · 2023 · Cells
  52. Neurodegenerative disorders share common features of “loss of function” states of a proposed mechanism of nervous system functions
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  53. Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with Alzheimer's disease: a positron emission tomography study
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  54. Posterior Cingulate Cortex Hypometabolism in Non-Amnestic Variants of Alzheimer’s Disease
    David Bergeron, Jean‐Mathieu Beauregard, Jean-Guimond, Jean‐Paul Soucy, Louis Verret, Stéphane P. Poulin, Jordi A. Matías‐Guiu, María Nieves Cabrera‐Martín, Rémi W. Bouchard, Robert Jr Laforce · 2020 · Journal of Alzheimer s Disease
  55. Measurement precision across cognitive domains in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) data set.
    Paul K. Crane, Seo‐Eun Choi, Michael K. Lee, Phoebe Scollard, Ruth Elizabeth Sanders, Brandon Skylar Klinedinst, Connie Y. Nakano, Emily H. Trittschuh, Jesse B Mez, Andrew J. Saykin et al. · 2023 · Neuropsychology
  56. Agmatine as a novel intervention for Alzheimer's disease: Pathological insights and cognitive benefits
    Raj Katariya, Shivkumar S. Sammeta, Mayur Bhimrao Kale, Nandkishor Ramdas Kotagale, Milind Janrao Umekar, Brijesh Gulabrao Taksande · 2024 · Ageing Research Reviews
  57. Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation
    Katalin Völgyi, Krisztina Háden, Viktor Kis, Péter Gulyássy, Kata Badics, Balázs A. Györffy, Attila Simor, Zoltán Szabó, Tamás Janáky, László Drahos et al. · 2016 · Molecular Neurobiology
  58. Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study
    Takuya Yagi, Michio Kanekiyo, Junichi Ito, Ryoko Ihara, Kazushi Suzuki, Atsushi Iwata, Takeshi Iwatsubo, Ken Aoshima, Alzheimer’s Disease Neuroimaging Initiative, Japanese Alzheimer's Disease Neuroimaging Initiative · 2019 · Alzheimer s & Dementia Translational Research & Clinical Interventions
  59. The Structural Basis of Amyloid Strains in Alzheimer’s Disease
    Lee Makowski · 2019 · ACS Biomaterials Science & Engineering
  60. Molecular and cellular pathology of monogenic Alzheimer’s disease at single cell resolution
    Federica Marinaro, Moritz Haneklaus, Zhechun Zhang, Alessio Strano, Lewis Evans, Louis‐François Handfield, Natalie Sarah Ryan, Nick C. Fox, Martin Hemberg, Sharad Ramanathan et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  61. MRI-based automated diagnosis of Alzheimer’s disease using Alzh-Net deep learning model
    Shashank Venkat, Tanmay Ghodeswar, Prashik Chavan, Senthil Kumar Narayanasamy, Kathiravan Srinivasan · 2024 · Biomedical Signal Processing and Control
  62. Key biomarkers in Alzheimer’s disease: Insights for diagnosis and treatment strategies
    Ruqaiya Jamal, Mohammad Abuzar Shaikh, Mohamad Taleuzzaman, Ziyaul Haque, Mohammed Albratty, Md Shamsher Alam, Hafiz Antar Makeen, Khalid A. Zoghebi, Safaa Fathy Saleh · 2025 · Journal of Alzheimer s Disease
  63. A Tutorial for Speech-Language Pathologists: Physical Activity and Social Engagement to Prevent or Slow Cognitive Decline in Older Adults
    Janet Everly, Jamie Plummer, Matthew C. Lohman, Jean Neils‐Strunjas · 2022 · American Journal of Speech-Language Pathology
  64. Altered large‐scale dynamic connectivity patterns in Alzheimer's disease and mild cognitive impairment patients: A machine learning study
    Rixing Jing, Pindong Chen, Yongbin Wei, Juanning Si, Yuying Zhou, Dawei Wang, Chengyuan Song, Hongwei Yang, Zengqiang Zhang, Hongxiang Yao et al. · 2023 · Human Brain Mapping
  65. Cost-Sensitive Weighted Contrastive Learning Based on Graph Convolutional Networks for Imbalanced Alzheimer’s Disease Staging
    Yan Hu, Jun Wang, Hao Zhu, Juncheng Li, Jun Shi · 2024 · IEEE Transactions on Medical Imaging
  66. Delineating the Heterogeneity of Alzheimer’s Disease and Mild Cognitive Impairment Using Normative Models of Dynamic Brain Functional Networks
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  67. Proteomic signatures of neuroinflammation in Alzheimer’s disease, multiple sclerosis and ischemic stroke
    Camilla Thygesen, Martin R. Larsen, Bente R. Finsen · 2019 · Expert Review of Proteomics
  68. Elevations in Serum Dickkopf-1 and Disease Progression in Community-Dwelling Older Adults With Mild Cognitive Impairment and Mild-to-Moderate Alzheimer’s Disease
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  69. Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl–Pyridazine Moiety for the Potential Treatment of Alzheimer’s Disease
    Mohamed Elsawalhy, Adel A.‐H. Abdel‐Rahman, Ebtesam A. Basiony, Salma A. Ellithy, Allam A. Hassan, Eman S. Abou‐Amra, A. E.‐H. A. A. ISMAIL, Abdulrahman Abdulaziz Almehizia, Mohamed Abdulrahman Al-Omar, Ahmed Mohamed Naglah et al. · 2024 · Pharmaceuticals
  70. Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals
    Luigi Lorenzini, Lyduine Eisa Collij, Niccoló Tesi, Natàlia Vilor‐Tejedor, Silvia Ingala, Kaj Blennow, Christopher Foley, Giovanni Battista Frisoni, Sven Haller, Henne H. Holstege et al. · 2024 · Alzheimer s & Dementia
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  83. Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants
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  90. Pairwise Correlation Analysis of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) Dataset Reveals Significant Feature Correlation
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  95. Anatomically Standardized Detection of MRI Atrophy Patterns in Early-Stage Alzheimer’s Disease
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  96. Identification of telomere-related genes associated with aging-related molecular clusters and the construction of a diagnostic model in Alzheimer's disease based on a bioinformatic analysis
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  97. Predicting the Risk of Alzheimer’s Disease and Related Dementia in Patients with Mild Cognitive Impairment Using a Semi-Competing Risk Approach
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  98. Amylin and pramlintide modulate γ-secretase level and APP processing in lipid rafts
    Youssef M. Mousa, Ihab M. Abdallah, Misako Hwang, Douglas R. Martin, Amal Kaddoumi · 2020 · Scientific Reports
  99. Heterogeneity of Alzheimer’s disease identified by neuropsychological test profiling
    Truc T.T. Nguyen, Hsun‐Hua Lee, Li‐Kai Huang, Chaur‐Jong Hu, Chih-Yang Yeh, Wei‐Chung Vivian Yang, Ming‐Chin Lin · 2023 · PLoS ONE
  100. Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults
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