The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Developments in the scientific understanding of osteoarthritis
Open accessAbstract
Osteoarthritis is often a progressive and disabling disease, which occurs in the setting of a variety of risk factors--such as advancing age, obesity, and trauma--that conspire to incite a cascade of pathophysiologic events within joint tissues. An important emerging theme in osteoarthritis is a broadening of focus from a disease of cartilage to one of the 'whole joint'. The synovium, bone, and cartilage are each involved in pathologic processes that lead to progressive joint degeneration. Additional themes that have emerged over the past decade are novel mechanisms of cartilage degradation and repair, the relationship between biomechanics and biochemical pathways, the importance of inflammation, and the role played by genetics. In this review we summarize current scientific understanding of osteoarthritis and examine the pathobiologic mechanisms that contribute to progressive disease.
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Cites
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Cited by
Hochberg, M. C., Altman, R. D., April, K. T., Benkhalti, M., Guyatt, G., McGowan, J., Towheed, T., Welch, V., Wells, G., & Tugwell, P. (2012) · Arthritis Care & Research · doi:10.1002/acr.21596 · Cited by 3,068
Nuesch, E., Dieppe, P., Reichenbach, S., Williams, S., Iff, S., & Juni, P. (2011) · BMJ · doi:10.1136/bmj.d1165 · Cited by 730
Genetic epidemiology of hip and knee osteoarthritis
Valdes, A. M., & Spector, T. D. (2011) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2010.191 · Cited by 256
Bennell, K. L., Egerton, T., Pua, Y.-H., Abbott, J. H., Sims, K., & Buchbinder, R. (2011) · Physical Therapy · doi:10.2522/ptj.20100430 · Cited by 31
Metadata
- Authors
- Abramson, S. B., & Attur, M.
- Venue
- Arthritis Research & Therapy
- Published
- 2009
- Volume
- 11
- Issue
- 3
- Pages
- 227
- ISSN
- 1478-6354 (ISSN-L)
- OpenAlex
- W2129531706
- Cited by
- 401
- References
- 72
- FWCI
- 20.93
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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