The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Pathogenesis of tendinopathies: inflammation or degeneration?
Open accessAbstract
The intrinsic pathogenetic mechanisms of tendinopathies are largely unknown and whether inflammation or degeneration has the prominent role is still a matter of debate. Assuming that there is a continuum from physiology to pathology, overuse may be considered as the initial disease factor; in this context, microruptures of tendon fibers occur and several molecules are expressed, some of which promote the healing process, while others, including inflammatory cytokines, act as disease mediators. Neural in-growth that accompanies the neovessels explains the occurrence of pain and triggers neurogenic-mediated inflammation. It is conceivable that inflammation and degeneration are not mutually exclusive, but work together in the pathogenesis of tendinopathies.
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Cites
Qi, J. H., Ebrahem, Q., Moore, N., Murphy, G., Claesson-Welsh, L., Bond, M., Baker, A., & Anand-Apte, B. (2003) · Nature Medicine · doi:10.1038/nm846 · Cited by 658
Murray, M. M., Spindler, K. P., Ballard, P., Welch, T. P., Zurakowski, D., & Nanney, L. B. (2007) · Journal of Orthopaedic Research · doi:10.1002/jor.20367 · Cited by 300
Yang, G., Im, H.-J., & Wang, J. H.-C. (2005) · Gene · doi:10.1016/j.gene.2005.08.006 · Cited by 282
Soon, M. Y. H., Hassan, A., Hui, J. H. P., Goh, J. C. H., & Lee, E. H. (2007) · The American Journal of Sports Medicine · doi:10.1177/0363546507300057 · Cited by 170
Local corticosteroid injection in sport: Review of literature and guidelines for treatment
Fredberg, U. (1997) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.1997.tb00129.x · Cited by 134
Cited by
Prevalence of Jumper's Knee among Elite Athletes from Different Sports: A Cross-sectional Study
Lian, Ø. B., Engebretsen, L., & Bahr, R. (2005) · The American Journal of Sports Medicine · doi:10.1177/0363546504270454 · Cited by 908
Millar, N. L., Silbernagel, K. G., Thorborg, K., Kirwan, P. D., Galatz, L. M., Abrams, G. D., Murrell, G. A. C., McInnes, I. B., & Rodeo, S. A. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-00234-1 · Cited by 801
Overuse injuries in sport: a comprehensive overview
Aicale, R., Tarantino, D., & Maffulli, N. (2018) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-018-1017-5 · Cited by 319
Inflammation is Present in Early Human Tendinopathy
Millar, N. L., Hueber, A. J., Reilly, J. H., Xu, Y., Fazzi, U. G., Murrell, G. A. C., & McInnes, I. B. (2010) · The American Journal of Sports Medicine · doi:10.1177/0363546510372613 · Cited by 287
Jo, C. H., Kim, J. E., Yoon, K. S., & Shin, S. (2012) · The American Journal of Sports Medicine · doi:10.1177/0363546512437525 · Cited by 248
Metadata
- Authors
- Abate, M., Gravare-Silbernagel, K., Siljeholm, C., Di Iorio, A., De Amicis, D., Salini, V., Werner, S., & Paganelli, R.
- Venue
- Arthritis Research & Therapy
- Published
- 2009
- Volume
- 11
- Issue
- 3
- Pages
- 235
- ISSN
- 1478-6354 (ISSN-L)
- OpenAlex
- W1986818994
- Cited by
- 571
- References
- 5
- FWCI
- 16.00
- Type
- journal article
- Language
- en
- Open access
- gold
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- Abate, M., Gravare-Silbernagel, K., Siljeholm, C., Di Iorio, A., De Amicis, D., Salini, V., Werner, S., & Paganelli, R. (2009). Pathogenesis of tendinopathies: inflammation or degeneration? Arthritis Research & Therapy. https://doi.org/10.1186/ar2723
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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