The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Choosing the right cell line for breast cancer research
Open accessAbstract
Breast cancer is a complex and heterogeneous disease. Gene expression profiling has contributed significantly to our understanding of this heterogeneity at a molecular level, refining taxonomy based on simple measures such as histological type, tumour grade, lymph node status and the presence of predictive markers like oestrogen receptor and human epidermal growth factor receptor 2 (HER2) to a more sophisticated classification comprising luminal A, luminal B, basal-like, HER2-positive and normal subgroups. In the laboratory, breast cancer is often modelled using established cell lines. In the present review we discuss some of the issues surrounding the use of breast cancer cell lines as experimental models, in light of these revised clinical classifications, and put forward suggestions for improving their use in translational breast cancer research.
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In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform
Katt, M. E., Placone, A. L., Wong, A. D., Xu, Z. S., & Searson, P. C. (2016) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2016.00012 · Cited by 754
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Kus-Liśkiewicz, M., Fickers, P., & Ben Tahar, I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010952 · Cited by 404
Altered calcium signaling in cancer cells
Stewart, T. A., Yapa, K. T. D. S., & Monteith, G. R. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2014.08.016 · Cited by 337
Metadata
- Authors
- Holliday, D. L., & Speirs, V.
- Venue
- Breast Cancer Research
- Published
- 2011-08
- Volume
- 13
- Issue
- 4
- Pages
- 215-215
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W1994930469
- Cited by
- 1,541
- References
- 65
- FWCI
- 7.26
- Type
- journal article
- Language
- en
- Open access
- gold
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