The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy
Open accessAbstract
Estrogen receptor (ER) has a crucial role in normal breast development and is expressed in the most common breast cancer subtypes. Importantly, its expression is very highly predictive for response to endocrine therapy. Current endocrine therapies for ER-positive breast cancers target ER function at multiple levels. These include targeting the level of estrogen, blocking estrogen action at the ER, and decreasing ER levels. However, the ultimate effectiveness of therapy is limited by either intrinsic or acquired resistance. Identifying the factors and pathways responsible for sensitivity and resistance remains a challenge in improving the treatment of breast cancer. With a better understanding of coordinated action of ER, its coregulatory factors, and the influence of other intracellular signaling cascades, improvements in breast cancer therapy are emerging.
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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
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Cited by
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
Revankar, C. M., Cimino, D. F., Sklar, L. A., Arterburn, J. B., & Prossnitz, E. R. (2005) · Science · doi:10.1126/science.1106943 · Cited by 2,302
Adams, B. D., Furneaux, H., & White, B. A. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0022 · Cited by 478
The c‐myc Promoter: Still MysterY and Challenge
(2008) · Advances in Cancer Research · doi:10.1016/s0065-230x(07)99004-1 · Cited by 211
Töröcsik, D., Szanto, A., & Nagy, L. (2009) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2009.02.002 · Cited by 82
Wang, C., Uray, I. P., Mazumdar, A., Mayer, J. A., & Brown, P. H. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1925-0 · Cited by 59
Metadata
- Authors
- Shao, W., & Brown, M.
- Venue
- Breast Cancer Research
- Published
- 2003-02
- Volume
- 6
- Issue
- 1
- Pages
- 39-52
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W1821437119
- Cited by
- 203
- References
- 6
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
