The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial
Open accessAbstract
Introduction: Critical illness polyneuromyopathy (CIPNM) is a common complication of critical illness presenting with muscle weakness and is associated with increased duration of mechanical ventilation and weaning period. No preventive tool and no specific treatment have been proposed so far for CIPNM. Electrical muscle stimulation (EMS) has been shown to be beneficial in patients with severe chronic heart failure and chronic obstructive pulmonary disease. Aim of our study was to assess the efficacy of EMS in preventing CIPNM in critically ill patients. Methods: One hundred and forty consecutive critically ill patients with an APACHE II score ≥ 13 were randomly assigned after stratification to the EMS group (n = 68) (age:61 ± 19 years) (APACHE II:18 ± 4, SOFA:9 ± 3) or to the control group (n = 72) (age:58 ± 18 years) (APACHE II:18 ± 5, SOFA:9 ± 3). Patients of the EMS group received daily EMS sessions. CIPNM was diagnosed clinically with the medical research council (MRC) scale for muscle strength (maximum score 60, <48/60 cut off for diagnosis) by two unblinded independent investigators. Duration of weaning from mechanical ventilation and intensive care unit (ICU) stay were recorded. Results: Fifty two patients could be finally evaluated with MRC; 24 in the EMS group and 28 in the control group. CIPNM was diagnosed in 3 patients in the EMS group as compared to 11 patients in the control group (OR = 0.22; CI: 0.05 to 0.92, P = 0.04). The MRC score was significantly higher in patients of the EMS group as compared to the control group [58 (33 to 60) vs. 52 (2 to 60) respectively, median (range), P = 0.04). The weaning period was statistically significantly shorter in patients of the EMS group vs. the control group [1 (0 to 10) days vs. 3 (0 to 44) days, respectively, median (range), P = 0.003]. Conclusions: This study suggests that daily EMS sessions prevent the development of CIPNM in critically ill patients and also result in shorter duration of weaning. Further studies should evaluate which patients benefit more from EMS and explore the EMS characteristics most appropriate for preventing CIPNM. Trial Registration Number: ClinicalTrials.gov NCT00882830
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Early exercise in critically ill patients enhances short-term functional recovery*
Burtin, C., Clerckx, B., Robbeets, C., Ferdinande, P., Langer, D., Troosters, T., Hermans, G., Decramer, M., & Gosselink, R. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181a38937 · Cited by 1,032
De Benedetti, F., Alonzi, T., Moretta, A., Lazzaro, D., Costa, P., Poli, V, Martini, A., Ciliberto, G., & Fattori, E. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119207 · Cited by 529 · cited 1×
“A possible role is suggested for IL-6, which reduces insulin-like growth factor 1 production, providing a major mechanism by which chronic inflammation inhibits hormonal anabolic action and affects growth [ 43 ].”
BackgroundHermans, G., Wilmer, A., Meersseman, W., Milants, I., Wouters, P. J., Bobbaers, H., Bruyninckx, F., & Van den Berghe, G. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200605-665oc · Cited by 368
Hamaoka, T., McCully, K. K., Quaresima, V., Yamamoto, K., & Chance, B. (2007) · Journal of Biomedical Optics · doi:10.1117/1.2805437 · Cited by 329
Cited by
Spruit, M. A., Singh, S. J., Garvey, C., ZuWallack, R., Nici, L., Rochester, C., Hill, K., Holland, A. E., Lareau, S. C., Man, W. D.-C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201309-1634st · Cited by 3,938
Physical Therapy for the Critically Ill in the ICU: A Systematic Review and Meta-Analysis*
Kayambu, G., Boots, R., & Paratz, J. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827ca637 · Cited by 438
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill
Friedrich, O., Reid, M. B., Van den Berghe, G., Vanhorebeek, I., Hermans, G., Rich, M. M., & Larsson, L. (2015) · Physiological Reviews · doi:10.1152/physrev.00028.2014 · Cited by 396
Devlin, J. W., Skrobik, Y., Gélinas, C., Needham, D. M., Slooter, A. J. C., Pandharipande, P. P., Watson, P. L., Weinhouse, G. L., Nunnally, M. E., Rochwerg, B., et al. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003259 · Cited by 372
Maffiuletti, N. A., Roig, M., Karatzanos, E., & Nanas, S. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-137 · Cited by 199
Self-citation
Metadata
- Authors
- Routsi, C., Gerovasili, V., Vasileiadis, I., Karatzanos, E., Pitsolis, T., Tripodaki, E., Markaki, V., Zervakis, D., & Nanas, S.
- Venue
- Critical Care
- Published
- 2010-04-28
- Volume
- 14
- Issue
- 2
- Pages
- R74-R74
- ISSN
- 1364-8535 (ISSN-L)
- OpenAlex
- W2008215444
- Cited by
- 321
- References
- 4
- FWCI
- 15.32
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial. https://app.cochat.ai/papers/10.1186/cc8987
- The paper
- Routsi, C., Gerovasili, V., Vasileiadis, I., Karatzanos, E., Pitsolis, T., Tripodaki, E., Markaki, V., Zervakis, D., & Nanas, S. (2010). Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial. Critical Care. https://doi.org/10.1186/cc8987
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
