The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
Open accessAbstract
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and endurance are decreased, whereas muscle fatigability is increased. There is a reduced proportion of type I fibers and an increase in type II fibers. Muscle atrophy occurs with a reduction in fiber cross-sectional area. Oxidative enzyme activity is decreased, and measurement of muscle bioenergetics during exercise reveals a reduced aerobic capacity. Deconditioning is probably very important mechanistically. Other mechanisms that may be of varying importance in individual patients include chronic hypercapnia and/or hypoxia, nutritional depletion, steroid usage, and oxidative stress. Potential therapies include exercise training, oxygen supplementation, nutritional repletion, and administration of anabolic hormones.
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Systemic oxidative stress in asthma, COPD, and smokers
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“products have been observed in patients with COPD during acute exacerbations [49].”
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Cited by
Sinden, N. J., & Stockley, R. A. (2010) · Thorax · doi:10.1136/thx.2009.130260 · Cited by 379
Quadriceps wasting and physical inactivity in patients with COPD
Shrikrishna, D., Patel, M., Tanner, R. J., Seymour, J. M., Connolly, B. A., Puthucheary, Z. A., Walsh, S. L. F., Bloch, S. A., Sidhu, P. S., Hart, N., et al. (2012) · European Respiratory Journal · doi:10.1183/09031936.00170111 · Cited by 331
Le Jemtel, T. H., Padeletti, M., & Jelic, S. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.046 · Cited by 324
Exacerbations and Time Spent Outdoors in Chronic Obstructive Pulmonary Disease
Donaldson, G. C., Wilkinson, T. M. A., Hurst, J. R., Perera, W. R., & Wedzicha, J. A. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200408-1054oc · Cited by 316
Barreiro, E., Peinado, V. I., Galdiz, J. B., Ferrer, E., Marin-Corral, J., Sánchez, F., Gea, J., & Barberà, J. A. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200908-1220oc · Cited by 272
Metadata
- Authors
- Jeffery Mador, M., & Bozkanat, E.
- Venue
- Respiratory Research
- Published
- 2001-05-02
- Volume
- 2
- Issue
- 4
- Pages
- 216-24
- ISSN
- 1465-9921 (ISSN-L)
- 1465-993X
- DOI
- 10.1186/rr60
- OpenAlex
- W2098142497
- Cited by
- 425
- References
- 82
- FWCI
- 6.30
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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