Severe septicemia, necrotizing fasciitis, and peritonitis due to Vibrio vulnificus in a patient undergoing continuous ambulatory peritoneal dialysis: A case report
Open accessAbstract
BACKGROUND: Chronic kidney disease, including end-stage renal disease, has been identified as a possible risk factor for primary septicemia and wound infection by Vibrio vulnificus. However, cases of severe septicemia, necrotizing fasciitis, and peritonitis caused by V. vulnificus in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) have not been described. We report a case of severe septicemia, necrotizing fasciitis, and peritonitis due to V. vulnificus in a patient undergoing CAPD after ingesting raw seafood. CASE PRESENTATION: A 37-year-old woman undergoing CAPD was admitted to the emergency room due to general weakness, fever, diarrhea, and abdominal pain. Although empirical intraperitoneal antibiotics were administered for the diagnosis of CAPD-related peritonitis, her fever did not subside. On hospital day 3, she had hemorrhagic bullae on both lower legs. We evaluated her recent food history, and found that she ate raw seafood before admission. She underwent emergency fasciotomy on the suspicion of necrotizing fasciitis by V. vulnificus infection. Finally, V. vulnificus was confirmed by 16S ribosomal ribonucleic acid gene sequencing using blood and peritoneal effluent fluid cultures. The administration of intraperitoneal ceftazidime and intravenous ciprofloxacin/ceftriaxone was continued for 4 weeks, and the patient completely recovered. CONCLUSIONS: Suspicion of V. vulnificus infection in vulnerable patients who ingest raw seafood is essential for prompt diagnosis, which could significantly improve patient outcomes.
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Oral ingestion of contaminated raw or uncooked seafood mainly leads to primary septicemia.
“Oral ingestion mainly leads to primary septicemia when people consume contaminated raw or uncooked seafood (Kim, Bae, Ma, & Kim, 2015).”
From <i>Vibrio vulnificus</i>in aquariums is a novel threat to marine mammals and public health (2018) · cites this paper as Kim, Bae, Ma, & Kim, 2015
The Background reports severe septicemia after the patient ingested raw seafood, supporting the link between ingestion and septicemia. It does not say that oral ingestion mainly leads to primary septicemia; the Conclusions describe this patient's peritonitis as preceding her septicemia. No page numbers are available in our copy. (LLM, conf=0.84)
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Horseman, M. A., & Surani, S. (2011) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2010.11.003 · Cited by 343 · see citing works
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<i>Vibrio vulnificus</i>in aquariums is a novel threat to marine mammals and public health
Li, M., Zhao, L., Ma, J., Zhao, N., Luo, J., Wang, C., Chen, L., Ma, G., Wang, Y., & He, H. (2018) · Transboundary and Emerging Diseases · doi:10.1111/tbed.12967 · Cited by 24 · see citing works
“Oral ingestion mainly leads to primary septicemia when people consume contaminated raw or uncooked seafood (Kim, Bae, Ma, & Kim, 2015).”
Background
- Authors
- Kim, C. S., Bae, E. H., Ma, S. K., & Kim, S. W.
- Affiliations
- Chonnam National University (KR)
- Corresponding author
- Kim, Soo Wan
- Venue
- BMC Infectious Diseases
- Published
- 2015-10-14
- Volume
- 15
- Issue
- 1
- Pages
- 422-422
- ISSN
- 1471-2334 (ISSN-L)
- PMC
- PMC4606901
- OpenAlex
- W1961632976
- Cited by
- 12
- References
- 1
- Citations by year
- 2025: 4 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Infectious Diseases (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future Planning (2013R1A2A2A01067611)
- the Pioneer Research Center Program through the National Research Foundation of Korea funded by the Ministry of Science, ICT &Future Planning (2014M3C1A3053036)
- a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (HI14C2084)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Vibrio bacteria research studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Infections and bacterial resistance
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Keywords
- Vibrio vulnificus, septicemia, necrotizing fasciitis, peritonitis, continuous ambulatory peritoneal dialysis, fasciotomy, 16S rRNA gene sequencing, end-stage renal disease, intraperitoneal antibiotics, ceftazidime, ciprofloxacin, ceftriaxone
- MeSH terms
- Adult, Anti-Bacterial Agents, Ceftazidime, Ceftriaxone, Female, Humans, Peritoneal Dialysis, Continuous Ambulatory, Peritonitis, RNA, Ribosomal, 16S, Vibrio Infections, Sepsis, Fasciitis, Necrotizing, Vibrio vulnificus
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