Cognitive behavioral group therapy for panic disorder in a general clinical setting: a prospective cohort study with 12 to 31-years follow-up
Open accessPublished version of a preprint
Abstract
Background: The long-term prognosis after cognitive behavioral therapy (CBT) in outpatient groups for panic disorder and agoraphobia is not well known. The purpose of this study was to assess long-term outcomes in terms of psychological health, health-related quality of life (HRQoL), quality of life (QoL) and treatment satisfaction after CBT for panic disorder and agoraphobia. Methods: The sample consisted of 68 patients (61% response rate), who were assessed at pretreatment; at the start and end of treatment; and after 3 months, after 1 year, and over the long term (M = 24 years; SD = 5.3; range: 12 to 31 years). The main outcome was the total score on the Phobic Avoidance Rating Scale (PARS-total). At long-term follow-up, HRQoL was measured with the RAND-12 questionnaire, and QoL was measured with two questions from the “Study on European Union Statistics on Income and Living Conditions”. Patient experiences and treatment satisfaction were assessed by the Generic Short Patient Experiences Questionnaire. A marginal longitudinal model was applied to study the main outcome. Results: The effect size of the long-term change (mean change/ pooled SD) in the PARS-total score was (− 1.6, p < 0.001) and was stable over time. A PARS-total score reduction of 50% was found in 98% of patients at the long-term follow-up. The patients’ HRQoL and QoL were similar to the expected scores for the general Norwegian population. Of the patients, 95% reported high to very high satisfaction with the CBT, and 93% reported large treatment benefits. Conclusions: To the best of our knowledge, this study has the longest follow-up after group CBT for panic disorder and agoraphobia, showing a good prognosis in ≥93% of the participating patients.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
ACT significantly improved both primary and comorbid insomnia and sleep quality across clinical populations.
“A systematic review has shown that ACT significantly improved both primary and comorbid insomnia and sleep quality across clinical populations [80].”
From Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice. (2026) · cites this paper as [80]
The Results and Discussion (pages not provided) report outcomes of group cognitive behavioral therapy for panic disorder, not ACT for insomnia. Searches for ACT, insomnia, sleep quality, and a systematic review found no passage addressing the attributed claim. (LLM, conf=0.78)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients
Beck, A. T., Steer, R. A., Ball, R., & Ranieri, W. F. (1996) · Journal of Personality Assessment · doi:10.1207/s15327752jpa6703_13 · Cited by 5,965 · cited 3× · see citing works
“Level of depression was assessed by the Beck Depression Inventory (BDI) [19], the degree of catastrophic interpretations of somatic symptoms by the Body Sensations Questionnaire (BSQ) [20], the fear of fear by the Agoraphobic Cognitions Questionnaire (ACQ) [20] and Agoraphobic Cognitions Scale (ACS) [21], and the degr…”
MethodClark, D. M. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90011-2 · Cited by 2,422 · cited 1× · see citing works
“The patients were repeatedly encouraged to use diaries for recording anxiety ratings, noting daily homework assignments, discussing dysfunctional thoughts, and personally monitoring the gains made in therapy [17].”
BackgroundChambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.52.6.1090 · Cited by 1,247 · cited 3× · see citing works
“Level of depression was assessed by the Beck Depression Inventory (BDI) [19], the degree of catastrophic interpretations of somatic symptoms by the Body Sensations Questionnaire (BSQ) [20], the fear of fear by the Agoraphobic Cognitions Questionnaire (ACQ) [20] and Agoraphobic Cognitions Scale (ACS) [21], and the degr…”
MethodChambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.52.6.1090 · Cited by 1,247 · see citing works
A Guide to Treatments that Work
Nathan, P. E., & Gorman, J. M. (2007) · Oxford University Press eBooks · doi:10.1093/med/9780195304145.001.0001 · Cited by 1,082 · cited 1× · see citing works
“Antidepressant medication use is well documented [3], and there is also empirical evidence for less trad-”
BackgroundThe Mobility Inventory for Agoraphobia
Chambless, D. L., Caputo, G. C., Jasin, S. E., Gracely, E. J., & Williams, C. (1985) · Behaviour Research and Therapy · doi:10.1016/0005-7967(85)90140-8 · Cited by 775 · cited 3× · see citing works
“Level of depression was assessed by the Beck Depression Inventory (BDI) [19], the degree of catastrophic interpretations of somatic symptoms by the Body Sensations Questionnaire (BSQ) [20], the fear of fear by the Agoraphobic Cognitions Questionnaire (ACQ) [20] and Agoraphobic Cognitions Scale (ACS) [21], and the degr…”
MethodA guide to treatments that work
(2015) · Oxford Clinical Psychology · doi:10.1093/med:psych/9780195304145.001.0001 · Cited by 647 · see citing works
Correlated physical and mental health summary scores for the SF-36 and SF-12 Health Survey, V.1
Farivar, S. S., Cunningham, W. E., & Hays, R. D. (2007) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-5-54 · Cited by 412 · see citing works
van Dis, E. A. M., van Veen, S. C., Hagenaars, M. A., Batelaan, N. M., Bockting, C. L. H., van den Heuvel, R. M., Cuijpers, P., & Engelhard, I. M. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.3986 · Cited by 335 · cited 1× · see citing works
“Our results correspond well with previous shorterterm studies on the treatment of panic disorder and agoraphobia [2, 4].”
ResultQuality of life impairment in generalized anxiety disorder, social phobia, and panic disorder
Barrera, T. L., & Norton, P. J. (2009) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2009.07.011 · Cited by 308 · cited 1× · see citing works
“often associated with impairments in a wide range of life areas [1].”
BackgroundBrown, T. A., & Barlow, D. H. (1995) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.63.5.754 · Cited by 262 · see citing works
Pompoli, A., Furukawa, T. A., Imai, H., Tajika, A., Efthimiou, O., & Salanti, G. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011004.pub2 · Cited by 142 · see citing works
Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland
Durham, R., Chambers, J. A., Power, K., Sharp, D., Macdonald, R. R., Major, K., Dow, M., & Gumley, A. I. (2005) · Health Technology Assessment · doi:10.3310/hta9420 · Cited by 122 · see citing works
TYRER, P., SEIVEWRIGHT, H., & JOHNSON, T. (2004) · Psychological Medicine · doi:10.1017/s0033291704002569 · Cited by 119 · see citing works
Sjetne, I. S., Bjertnæs, Ø. A., Olsen, R. V., Iversen, H. H., & Bukholm, G. (2011) · BMC Health Services Research · doi:10.1186/1472-6963-11-88 · Cited by 109 · cited 1× · see citing works
“Patient experiences and treatment satisfaction were assessed by the Generic Short Patient Experiences Questionnaire (GS-PEQ), which consists of ten generic core questions that cover the essential dimensions of users’ experiences with a range of specialist health care services [26].”
MethodQuality of Life and Pharmacoeconomics: An Introduction
Cramer, J. A., & Spilker, B. (1998) · Cited by 77 · see citing works
Hovland, A., Nordhus, I. H., Sjøbø, T., Gjestad, B. A., Birknes, B., Martinsen, E. W., Torsheim, T., & Pallesen, S. (2012) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465812000446 · Cited by 60 · cited 2× · see citing works
“itional forms of treatment, such as physical exercise [4].”
BackgroundResultSelf-citationCognitive-Behavioral Group Therapy for Panic Disorder in the General Clinical Setting
Martinsen, E. W., Olsen, T., Tonset, E., Nyland, K. E., & Aarre, T. F. (1998) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v59n0808 · Cited by 57 · cited 1× · see citing works
“Thus, we wanted to address these research needs by extending a prior study (N = 83) published in 1998 [15].”
BackgroundSelf-citationDurham, R. C., Higgins, C., Chambers, J. A., Swan, J. S., & Dow, M. G. T. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.09.017 · Cited by 51 · see citing works
von Brachel, R., Hirschfeld, G. H. F., Berner, A., Willutzki, U., Teismann, T., Cwik, J. C., Velten, J., Schulte, D., & Margraf, J. (2019) · Psychotherapy and Psychosomatics · doi:10.1159/000500188 · Cited by 49 · see citing works
Imai, H., Tajika, A., Chen, P., Pompoli, A., & Furukawa, T. A. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011170.pub2 · Cited by 38 · cited 1× · see citing works
“Moreover, a Cochrane review recommended that studies in this field include broader measures of quality of life (QoL) in addition to standard disease-specific outcomes [8].”
BackgroundThe Phobic Avoidance Rating Scale: a psychometric evaluation of an interview-based scale.
Hoffart, A., Friis, S., & Martinsen, E. W. (1989) · PubMed · Cited by 28 · see citing works
Self-citationAssessment of fear of fear among Agoraphobic patients: The Agoraphobic Cognitions Scale
Hoffart, A., Friis, S., & Martinsen, E. W. (1992) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/bf00965173 · Cited by 22 · cited 3× · see citing works
“Level of depression was assessed by the Beck Depression Inventory (BDI) [19], the degree of catastrophic interpretations of somatic symptoms by the Body Sensations Questionnaire (BSQ) [20], the fear of fear by the Agoraphobic Cognitions Questionnaire (ACQ) [20] and Agoraphobic Cognitions Scale (ACS) [21], and the degr…”
BackgroundSelf-citationHoffart, A., Hedley, L. M., Svanøe, K., & Sexton, H. C. (2014) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.1934 · Cited by 8 · cited 3× · see citing works
“of patients is also observed in other studies with a very long follow-up period [13, 14].”
BackgroundResultEffectiveness of cognitive-behavioral group therapy for panic disorder in a specialized unit.
Prats, E., Domínguez‐Clavé, E., Rosado, S., Pailhez, G., Bulbena, A., & Fullana, M. A. (2014) · PubMed · Cited by 7 · see citing works
Agoraphobia With and Without Panic Disorder
Hoffart, A., Hedley, L. M., Svanøe, K., Langkaas, T. F., & Sexton, H. C. (2015) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000419 · Cited by 5 · cited 3× · see citing works
“of patients is also observed in other studies with a very long follow-up period [13, 14].”
BackgroundResult
Flagged first, then by citations
Research works printed but not linked: 1
- [27]Cohen J Statistical Power analysis for the behavioral sciences., 1 edn 1988 New York Academic Press
Cited by
Sorted by citations
Correlates of Quality of Life in Anxiety Disorders: Review of Recent Research
Wilmer, M. T., Anderson, K., & Reynolds, M. (2021) · Current Psychiatry Reports · doi:10.1007/s11920-021-01290-4 · Cited by 150 · see citing works
The Bergen 4-day treatment for panic disorder: implementation in a rural clinical setting
Eide, T. O., Hjelle, K. M., Sætre, I. U., Solem, S., Olsen, T., Sköld, R. O., Kvale, G., Hansen, B. K. A., & Hagen, K. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04812-x · Cited by 13 · see citing works
“As there is a lack of longterm follow-up studies on CBT for PD [37], the longterm effectiveness of this treatment format needs further examination.”
BackgroundSelf-citationKwek, S. Q., Yeo, T. M., Teo, J. Y. C., Seah, A. C. W., Kai Ning, J. P., & Wang, W. (2025) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvaf084 · Cited by 11 · see citing works
Thesen, T., Himle, J. A., Martinsen, E. W., Walseth, L. T., Thorup, F., Gallefoss, F., & Jonsbu, E. (2021) · Journal of Medical Internet Research · doi:10.2196/33631 · Cited by 9 · see citing works
“Cognitive behavioral therapy is often more powerful when maladaptive cognitions are challenged during systematic exposure [27].”
BackgroundSelf-citationDambi, J. M., Shava, B. K., Tunduwani, T. D., Chitiyo, C., Takaona, T. L., Mashunye, T., Dzapasi, L., & Chibanda, D. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-079842 · Cited by 4 · see citing works
León-Quismondo, L., Lahera, G., Liria, A. F., López‐Ríos, F., Saiz-Ruiz, J., Ibáñez, Á., García‐Montes, J. M., & Stiles, B. J. (2025) · Psicothema · doi:10.70478/psicothema.2025.37.04 · Cited by 3 · see citing works
The bergen 4-day treatment for panic disorder: a longer-term follow-up
Eide, T. O., Hansen, B., Hjelle, K., Solem, S., Wheaton, M., Björgvinsson, T., Kvale, G., & Hagen, K. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06527-7 · Cited by 2 · see citing works
“For instance, one study might use the Phobic Avoidance Rating Scale and an arbitrary definition of 50% reduction as response [11], and another study used the Panic and Agoraphobia Scale (PAS) and a score of 8 or less as a definition of remission [40].”
InfluentialLukaschek, K., Haas, C., Wannemüller, A., Brettschneider, C., Dreischulte, T., Margraf, J., Gensichen, J. S., & on behalf of the PARADIES study group (2023) · PLoS ONE · doi:10.1371/journal.pone.0287718 · Cited by 3 · see citing works
Eide, T. O., Olsen, T., Hansen, H., Hansen, B. K. A., Solem, S., & Hagen, K. (2025) · BMC Psychiatry · doi:10.1186/s12888-024-06445-0 · Cited by 2 · see citing works
Self-citationAdvances in anxiety research: Neurocognitive mechanisms and clinical applications
Luo, Y., Qin, S., Zhu, Y., Li, Z., Zhang, Z., Jin, Z., & Xu, P. (2023) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2023-0801 · Cited by 1 · see citing works
Long-term follow-up of the Bergen 4-day treatment for panic disorder during the COVID-19 pandemic
Hjelle, K. M., Eide, T. O., Thorsen, A. L., Kvale, G., Hagen, K., Wheaton, M. G., Björgvinsson, Þ., & Hansen, B. K. A. (2024) · Cogent Psychology · doi:10.1080/23311908.2024.2402603 · Cited by 1 · see citing works
“Many studies that include long-term outcomes include data from only a portion of the initial sample due to a considerable amount of missing data. additionally, some follow-up studies did not systematically record information about the years between acute and long-term outcomes. this could result in the exclusion of in…”
InfluentialApproaches to panic attack symptoms in cardiology outpatients
Örüm, D., Abuş, S., & Kapıcı, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-93701-2 · Cited by 1 · see citing works
“In cognitive behavioral therapy of PD, cognitive restructuring, relaxation exercises and exposure practices are used together with psychopharmacological treatment, and the best results are achieved in this way 39 .”
Yığman, F., Efe, C., Ekici, E., & Özdel, K. (2021) · International Journal of Cognitive Therapy · doi:10.1007/s41811-021-00099-6 · Cited by 1 · see citing works
Pre-Sleep Anxiety: Mechanisms and Therapeutic Approaches in Clinical Practice.
Song, S., Irfan, M., Tahir, Z., Garrison, K. A., & Ziskind, S. (2026) · Current Sleep Medicine Reports · doi:10.1007/s40675-026-00370-2
Importance of Interpersonal Relationships in CBGT
Badley, A. (2020) · doi:10.15760/honors.968
Kharrazi, N., Moffett, L. A., & Denduluri, M. S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91497-0.00116-8
Psychotherapy for Anxiety Disorders
任, 帅. (2024) · Advances in Psychology · doi:10.12677/ap.2024.145280
Pilipenko, N., Desai, K. M., & Garcia, A. V. (2026) · Springer eBooks · doi:10.1007/978-3-032-12819-5_3
Understanding Psychotherapy Services: Crash Course for Physicians
Pilipenko, N. (2026) · Springer eBooks · doi:10.1007/978-3-032-12819-5_10
العلاج المعرفي السلوكي الموجز لاضطراب الهلع
سنوساوي, ع. ا. (2026) · مجلة العلوم الاجتماعية و الانسانية · doi:10.67603/jossh.v16i01.10159
Nasif, J., Chong, A. S. S., & Ahmad, M. (2026) · Behavioral Sciences · doi:10.3390/bs16091682
“These findings are consistent with Bilet et al. (2020), who reported that CBT improved health-related and overall quality of life among individuals with panic disorder.”
- Authors
- Bilet, T., Olsen, T., Andersen, J. R., & Martinsen, E. W.
- Affiliations
- Helse Førde (NO)
- Western Norway University of Applied Sciences (NO)
- Oslo University Hospital (NO)
- Corresponding author
- Andersen, John Roger
- Venue
- BMC Psychiatry
- Published
- 2020-05-24
- Volume
- 20
- Issue
- 1
- Pages
- 259-259
- ISSN
- 1471-244X (ISSN-L)
- PMC
- PMC7247216
- OpenAlex
- W3027738197
- Cited by
- 21
- References
- 25
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 1
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Psychiatry (publishedVersion, cc-by)
- Research Square (acceptedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Social Science Open Access Repository (GESIS – Leibniz Institute for the Social Sciences) (submittedVersion, cc-by)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by)
- Funders
- Førde Hospital Trust
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- cognitive behavioral therapy, panic disorder, agoraphobia, group therapy, long-term outcomes, prognosis, health-related quality of life, quality of life, treatment satisfaction, phobic avoidance, outpatient care
- MeSH terms
- Adult, Agoraphobia, Cognition, Female, Follow-Up Studies, Humans, Male, Prospective Studies, Psychotherapy, Group, Quality of Life, Cognitive Behavioral Therapy, Panic Disorder, Treatment Outcome, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review