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Poorer patient-reported knee function and quality of life, but not activity level, after revision ACL reconstruction compared with primary ACL reconstruction: a matched-pair analysis with a minimum 5-year follow-up
Open accessAbstract
Background: An appropriate method for comparing knee function and activity level between patients with primary and revision anterior cruciate ligament reconstruction (ACLR) is to perform a matched-group analysis. The aim was to assess and compare knee function, knee-related quality of life and activity level between patients with revision ACLR and primary ACLR at a minimum of 5 years of follow-up. Methods: Patients aged ≤ 40 years old who underwent revision ACLR between 2010 and 2015 and a matched control group (primary ACLR) (1:1) with age ± 2 years, year of ACLR, sex, and pre-injury sport and Tegner Activity Scale (TAS) were retrospectively identified in our clinic database. The preoperative Knee injury and Osteoarthritis Outcome Score (KOOS) and surgical data were extracted and analyzed. Patients were mailed KOOS and EQ-5D questionnaires at a minimum of 5-years after revision ACLR. Study-specific questions about knee function, limitation in sport, satisfaction, and activity level according to the TAS (all scales of 1–10, 10 best) were also asked by telephone. Results: Seventy-eight patients with a revision ACLR (mean age ± SD, 29.9 ± 6.0 years) matched with seventy-eight patients with a primary ACLR (30.2 ± 5.8 years) were included. The follow-up for the revision ACLR group was 7.0 ± 1.5 years and for the primary ACLR group 7.7 ± 1.6 years. The revision ACLR group reported poorer KOOS scores in all subscales (p < 0.05) except the Symptoms subscale, poorer EQ-5D VAS (mean 79.2 ± 20.1 vs 86.0 ± 20.1, p = 0.012), and less satisfaction with current knee function (median 7 (6–8) vs 8 (7–9), p < 0.001). Patients with revision ACLR also experienced greater limitation in sports (median 7 (4–8) vs 8 (6–9), p < 0.001). There were no significant differences in the EQ-5D (mean 0.86 ± 0.17 vs 0.89 ± 0.11, p = 0.427), activity level (median 2 (2–5) vs 4 (2–7), p = 0.229), or satisfaction with activity level (median 8 (5–9) vs 8 (6–10), p = 0.281) between the groups. Conclusions: At a minimum 5-year follow-up, the revision ACLR group reported poorer knee function and quality of life, less satisfaction with knee function and a greater limitation in sports but no differences in activity level and satisfaction with activity level compared with the primary ACLR group.
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“Clinicians use objective factors such as age, time from injury, and strength symmetry in clinical decision-making for return to sport after ACLR5–11; however, these alone do not fully explain why some athletes do not return to sport despite achieving adequate physical rehabilitation.12–15”
From Determinants of Psychological Readiness to Return to Sport After Anterior Cruciate Ligament Reconstruction (2026) · cites this paper as [14]
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Cited by
Sorted by citations
Murphy, T., Lyons, L., Mertz-Bynum, N., Lugin, A., Harkey, M. S., Kuenze, C., Baez, S., Myer, G. D., Diekfuss, J., & Petushek, E. (2026) · Journal of Athletic Training · doi:10.4085/1062-6050-0696.25
Metadata
- Authors
- Koca, F., Stålman, A., Vestberg, C., Cristiani, R., & Fältström, A.
- Affiliations
- Karolinska Institutet (SE)
- Linköping University (SE)
- Corresponding author
- Fältström, Anne
- Venue
- BMC Musculoskeletal Disorders
- Published
- 2023-10-23
- Volume
- 24
- Issue
- 1
- Pages
- 831-831
- ISSN
- 1471-2474 (ISSN-L)
- PMC
- PMC10594802
- OpenAlex
- W4387880833
- Cited by
- 15
- References
- 1
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 3
- FWCI
- 3.37
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Musculoskeletal Disorders (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DiVA (Linkoping University) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Linköping University
- Topics
- Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Foot and Ankle Surgery
- Health Sciences › Medicine › Surgery › Total Knee Arthroplasty Outcomes
- Keywords
- revision anterior cruciate ligament reconstruction, knee function, knee-related quality of life, activity level, Tegner score, KOOS, EQ-5D, patient satisfaction, sports participation, matched-pair analysis, long-term outcomes, knee osteoarthritis risk, knee swelling, knee stiffness, knee laxity
- MeSH terms
- Anterior Cruciate Ligament Injuries, Patient Reported Outcome Measures, Adult, Follow-Up Studies, Humans, Knee Joint, Quality of Life, Retrospective Studies, Matched-Pair Analysis
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