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Drug-induced liver injury associated with Complementary and Alternative Medicine: a review of adverse event reports in an Asian community from 2009 to 2014

Teo, Desmond Chun Hwee, Ng, Patricia Suet Leng, Tan, Siew Har, Lim, Adena Theen, Toh, Dorothy Su Lin, Chan, Sui Yung, Cheong, Han Hui·2016·BMC Complementary and Alternative Medicine
DOI 10.1186/s12906-016-1168-zPMC PMC4937524
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Crossref · 10.1186/s12906-016-1168-z

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  • Groups from Singapore presented two reports, with altogether 25 HILI cases that had been assessed for causality using RUCAM.

    “Groups from Singapore presented two reports, with altogether 25 HILI cases that had been assessed for causality using RUCAM.55,56”

    From Herb-induced Liver Injury in Asia and Current Role of RUCAM for Causality Assessment in 11,160 Published Cases (2020) · cites this paper as [56]

  • The second study published 10 years later by Teo et al. presented data from a retrospective analysis of spontaneous reports submitted to the national registry; respective causality gradings were extremely low due to incomplete case data, not unexpected under these study conditions.

    “The second study published 10 years later by Teo et al.56 presented data from a retrospective analysis of spontaneous reports submitted to the national registry; respective causality gradings were extremely low due to incomplete case data, not unexpected under these study conditions.”

    From Herb-induced Liver Injury in Asia and Current Role of RUCAM for Causality Assessment in 11,160 Published Cases (2020) · cites this paper as [56]

  • Another Singapore study of liver injury associated with CAM (review of adverse event reports 2009-2014) had 10 assessable HILI cases, with weak RUCAM scores from 0 to 2 for 9 patients and a score of 5 for 1 patient.

    “These data are at variance with another Singapore study of liver injury associated with CAM—a review of adverse event reports in an Asian community from 2009 to 2014, in which 10 assessable HILI cases provided weak RUCAM scores from 0 to 2 for 9 patients and a score of 5 for 1 patient.56”

    From Herb-induced Liver Injury in Asia and Current Role of RUCAM for Causality Assessment in 11,160 Published Cases (2020) · cites this paper as [56]

  • HMs are the leading cause of DILI in many Asian countries such as Korea, Thailand, and Singapore, accounting for 27.5%, 41.5%, and 61.4% respectively.

    “HMs are the leading cause of DILI in many Asian countries such as Korea [7], Thailand [17], and Singapore [18], and accounts for 27.5%, 41.5%, and 61.4% respectively.”

    From Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update (2024) · cites this paper as [18]

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Research works printed but not linked: 61

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Metadata

Authors
Teo, D. C. H., Ng, P. S. L., Tan, S. H., Lim, A. T., Toh, D. S. L., Chan, S. Y., & Cheong, H. H.
ORCID
Cheong, Han Hui
Venue
BMC Complementary and Alternative Medicine
Publisher
Springer Science and Business Media LLC
Published
2016-07-07
Volume
16
Issue
1
ISSN
1472-6882
DOI
10.1186/s12906-016-1168-z
PMC
PMC4937524
Cited by
34
References
2
Language
en

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