The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Implementation of flipped classroom combined with problem-based learning: an approach to promote learning about hyperthyroidism in the endocrinology internship
Open accessAbstract
BACKGROUND: With the development of medicine, new teaching methods, such as flipped classroom and problem-based learning (PBL), have received much attention in medical education. However, the implementation of flipped classroom combined with PBL in endocrinology education has not been well investigated. Considering that both two teaching methods may complement each other, therefore, the aim of this study was to evaluate students' learning effectiveness acceptability of the pedagogy between traditional lecture-based teaching methods and the combination of flipped classrooms with PBL teaching methods in the endocrinology internship. METHODS: 74 fourth-year medical students at the Bengbu Medical College were enrolled in the endocrinology internship. Hyperthyroidism was chosen for the content of this study. The participants were randomly allocated into either the combination group of flipped classroom with PBL (CG) or the traditional lecture-based classroom group (TG). Both a pre-quiz and a post-quiz were conducted before and after the classes, respectively. All questions in the quizzes were classified into two aspects, basic theoretical knowledge and clinical case analyses based on the Bloom's Taxonomy. The scores were compared and students were required to complete the questionnaire to evaluate their perceptions and experience. RESULTS: The mean post-quiz scores of both the TG and the CG were higher than those of the pre-quiz. Additionally, the post-quiz showed that students in the CG had significantly higher scores in the TG. Further analysis found that after class, only the difference in clinical case analysis between CG and TG was significant. The scores of all items in the questionnaires were higher in the CG than in the TG. More students agreed that the combined teaching method could help to improve their performance, at the same time, it could increase their workload. CONCLUSIONS: The combination of the flipped classroom and PBL teaching approach could be a better option over the traditional lecture-based classroom in the teaching of hyperthyroidism during endocrinology internship, although it can increase students' workload. To be widely accepted and implemented, further optimizations are required.
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“but in 9 studies the overall satisfaction scores for the PBL program were neutral [76, 111–116] or negative [117, 118].”
From Effectiveness of problem-based learning methodology in undergraduate medical education: a scoping review (2022) · cites this paper as [76]
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(2001) · Cited by 13,930
Flip Your Classroom: Reach Every Student in Every Class Every Day
Sams, A., & Bergmann, J. (2012) · Medical Entomology and Zoology · Cited by 3,810
Effectiveness of Problem-based Learning Curricula: Research and Theory
Colliver, J. A. (2000) · Academic Medicine · doi:10.1097/00001888-200003000-00017 · Cited by 917
A systematic review of the effectiveness of flipped classrooms in medical education
Chen, F., Lui, A. M., & Martinelli, S. M. (2017) · Medical Education · doi:10.1111/medu.13272 · Cited by 822
McLean, S. F. (2016) · Journal of Medical Education and Curricular Development · doi:10.4137/jmecd.s20377 · Cited by 759
The evidence for ‘flipping out’: A systematic review of the flipped classroom in nursing education
Betihavas, V., Bridgman, H., Kornhaber, R. A., & Cross, M. (2015) · Nurse Education Today · doi:10.1016/j.nedt.2015.12.010 · Cited by 658
Advances in medical education and practice: student perceptions of the flipped classroom
Ramnanan, C. J., & Pound, L. D. (2017) · Advances in Medical Education and Practice · doi:10.2147/amep.s109037 · Cited by 349
Twelve tips for “flipping” the classroom
Moffett, J. (2014) · Medical Teacher · doi:10.3109/0142159x.2014.943710 · Cited by 307
Team-based learning (TBL) in the medical curriculum: better than PBL?
Burgess, A. W., Bleasel, J. F., Haq, I., Roberts, C., Garsia, R. J., Robertson, T., & Mellis, C. (2017) · BMC Medical Education · doi:10.1186/s12909-017-1068-z · Cited by 235
Morton, D. A., & Colbert‐Getz, J. M. (2016) · Anatomical Sciences Education · doi:10.1002/ase.1635 · Cited by 234
Research works printed but not linked: 6
- Hu X, Chen W, Sun W, Yu L, Shi Z, Jin G. Application of the teaching method combining PBL with CBL in resident standardization training in the department of endocrinology. Chinese J Gen Prac. 2017;15(7):1236–8.
- Zhou R, Li C, Chen L, Wu X. Application of flipped classroom combined with PBL in physiology teaching. Basic Med Educ. 2018;20(1):12–4.
- Yang R, Jia Q, Wang Y, Ma S, Gao Q, Guan S. Application of flipped classroom combined with problem-based learning teaching mode in the teaching of the structure and function of human body. J Qiqihar University of Medicine. 2017;38(1):89–90.
- Ma X, Huang Y, Song Z, Zhang X. Application of PBL combined flipped classroom in biochemistry and molecular biology teaching. J Jining Medical University. 2018(5):375–8.
- Sun M, Zhao W, Tan S, Zhang F, Bu R. Application of PBL combined with flipped classroom in internship instruction in the department of urology. Basic Med Educ. 2018;20(8):680–3.
- Mi W, Dong Z, Lian W, Shi T, Jie W. Studying on the application of flipped classroom model on PBL in teaching of preventive medicine. The Chinese Health Serv Manage. 2017;34(8):615–8.
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Metadata
- Authors
- Hu, X., Zhang, H., Song, Y., Wu, C., Yang, Q., Shi, Z., Zhang, X., & Chen, W.
- Affiliations
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Corresponding author
- Hu, Xiaolei
- Chen, Weidong
- Venue
- BMC Medical Education
- Published
- 2019-07-30
- Volume
- 19
- Issue
- 1
- Pages
- 290-290
- ISSN
- 1472-6920 (ISSN-L)
- PMC
- PMC6668058
- OpenAlex
- W2965171981
- Cited by
- 105
- References
- 29
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 20 · 2023: 18 · 2022: 21 · 2021: 9 · 2020: 18 · 2019: 1
- FWCI
- 33.08
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Medical Education (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Quality Project for Undergraduate Teaching, Bengbu Medical College (2017jyxm62)
- Topics
- Social Sciences › Education › Innovative Teaching Methods
- Social Sciences › Education › Innovations in Medical Education
- Social Sciences › Education › Problem and Project Based Learning
- Keywords
- flipped classroom, problem-based learning, hyperthyroidism, medical students, lecture method comparison, clinical case analysis, Bloom's taxonomy, student perceptions, student workload
- MeSH terms
- China, Endocrinology, Female, Humans, Hyperthyroidism, Internship and Residency, Male, Surveys and Questionnaires, Students, Medical, Teaching, Problem-Based Learning, Young Adult
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